Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Christine S. Siegismund"'
Autor:
Dirk Lassner, Christine S. Siegismund, Uwe Kühl, Maria Rohde, Andrea Stroux, Felicitas Escher, Heinz-Peter Schultheiss
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-11 (2018)
Abstract Background Enteroviral cardiomyopathy is a life-threatening disease, and detection of enterovirus (EV) RNA in the initial endomyocardial biopsy is associated with adverse prognosis and increased mortality. Some patients with EV infection may
Externí odkaz:
https://doaj.org/article/f1e65e54b3a14ca9952d2d2fa549bfde
Autor:
Christine S. Siegismund, Maria Rohde, Uwe Kühl, Felicitas Escher, Heinz Peter Schultheiss, Dirk Lassner
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 14, Iss 4, Pp 224-234 (2016)
MicroRNAs (miRNAs) can be found in a wide range of tissues and body fluids, and their specific signatures can be used to determine diseases or predict clinical courses. The miRNA profiles in biological samples (tissue, serum, peripheral blood mononuc
Externí odkaz:
https://doaj.org/article/ceadcc21065d476bba53ae4bf7e5ce93
Autor:
Ingo Schäfer, Dirk Lassner, Peter Seibel, Uwe Kühl, Heinz-Peter Schultheiss, Christine S. Siegismund
Publikováno v:
Mitochondrion. 30:236-247
We developed a multiplex fragment length analysis (MFLA) for clearly assigning mitochondrial haplogroups mostly endemic in Europe for future cardiac diagnostics. As a technical proof, 23 commonly used human cell lines were haplotyped as reference sta
Autor:
Maria Rohde, Dirk Lassner, Heinz-Peter Schultheiss, Christine S. Siegismund, Felicitas Escher, Uwe Kühl
Publikováno v:
Genomics, Proteomics & Bioinformatics
Genomics, Proteomics & Bioinformatics, Vol 14, Iss 4, Pp 224-234 (2016)
Genomics, Proteomics & Bioinformatics, Vol 14, Iss 4, Pp 224-234 (2016)
MicroRNAs (miRNAs) can be found in a wide range of tissues and body fluids, and their specific signatures can be used to determine diseases or predict clinical courses. The miRNA profiles in biological samples (tissue, serum, peripheral blood mononuc
Autor:
Heinz-Peter Schultheiss, Maria Rohde, Felicitas Escher, Dirk Lassner, Christine S. Siegismund, Uwe Kühl, Andrea Stroux
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-11 (2018)
Journal of Translational Medicine
Journal of Translational Medicine
Background Enteroviral cardiomyopathy is a life-threatening disease, and detection of enterovirus (EV) RNA in the initial endomyocardial biopsy is associated with adverse prognosis and increased mortality. Some patients with EV infection may spontane
Autor:
Martina Gast, Dirk Lassner, Madlen Loebel, Carsten Tschoepe, Uwe Kuehl, Felicitas Escher, Heinz-Peter Schultheiss, Wolfgang Poller, Andrea Stroux, Xiaomin Wang, Michael Gross, Maria Rohde, Carsten Skurk, Christine S. Siegismund, Carmen Scheibenbogen
Publikováno v:
Circulation: Heart Failure. 8:605-618
Background— Investigation of disease pathogenesis confined to protein-coding regions of the genome may be incomplete because many noncoding variants are associated with disease. We aimed to identify novel predictive markers for the course of entero
Autor:
Ulrich Gross, Christine S. Siegismund, Heinz-Peter Schultheiss, Uwe Kühl, Dirk Lassner, Thomas Münzel, Friedrich Fruhwald, Norbert Frey, Reinhold P. Linke, Philip Wenzel, Felicitas Escher
Publikováno v:
European journal of heart failure. 20(4)
Aims To evaluate the influence of endomyocardial biopsy (EMB)-proven intramyocardial inflammation on mortality in patients with cardiac transthyretin amyloid (ATTR) or amyloid light-chain (AL) amyloidosis. Methods and results We included 54 consecuti
Publikováno v:
Microchimica Acta. 181:1647-1653
The diagnosis of cardiomyopathies by endomyocardial biopsy analysis is the gold standard for confirmation of causative reasons but is failing if a sample does not contain the area of interest due to focal pathology. Biopsies are revealing an extract
Autor:
Ulrich Gross, Felicitas Escher, Dirk Lassner, S. Elezkurtaj, Carsten Tschöpe, Uwe Kühl, Christine S. Siegismund, H.P. Schultheiss, Maria Rohde, Wolfgang Poller
Publikováno v:
European Heart Journal. 35:2186-2195
Improvement of clinical diagnostics of idiopathic giant cell myocarditis (IGCM) and cardiac sarcoidosis (CS), two fre- quently fatal human myocardial diseases. Currently, IGCM and CS are diagnosed based on differential patterns of inflam- matory cell
Autor:
Ulrich Gross, Dirk Lassner, Heinz-Peter Schultheiss, Uwe Kühl, Felicitas Escher, Carsten Tschöpe, Christine S. Siegismund, Maria Rohde
Publikováno v:
World Journal of Cardiovascular Diseases. :325-340
Myocarditis and dilated cardiomyopathy (DCM) are acute or chronic disorders of myocardium. The gold standard for final confirmation of causative reasons of these heart muscle diseases is the endomyocardial biopsy (EMB) analysis. Due to focal patholog