Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Christine S. Huang"'
Autor:
Cholpon Tilegenova, Saeed Izadi, Jianping Yin, Christine S. Huang, Jiansheng Wu, Diego Ellerman, Sarah G. Hymowitz, Benjamin Walters, Cleo Salisbury, Paul J. Carter
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
Some antibodies exhibit elevated viscosity at high concentrations, making them poorly suited for therapeutic applications requiring administration by injection such as subcutaneous or ocular delivery. Here we studied an anti-IL-13/IL-17 bispecific Ig
Externí odkaz:
https://doaj.org/article/7dd9a83f03f24159a13745cb1fdb0072
Autor:
Yu, Sun, Zechun, Peng, Xiaofei, Wei, Nianhui, Zhang, Christine S, Huang, Martin, Wallner, Istvan, Mody, Carolyn R, Houser
Publikováno v:
Progress in neurobiology. 218
Decreased expression of the δ subunit of the GABA
Autor:
Patrick G. Holder, Shion A. Lim, Christine S. Huang, Preeti Sharma, Yavuz S. Dagdas, Beyza Bulutoglu, Jonathan T. Sockolosky
Publikováno v:
Advanced Drug Delivery Reviews. 182:114112
Cytokines are a class of potent immunoregulatory proteins that are secreted in response to various stimuli and act locally to regulate many aspects of human physiology and disease. Cytokines play important roles in cancer initiation, progression, and
Autor:
Cholpon Tilegenova, Sarah G. Hymowitz, Cleo M. Salisbury, Saeed Izadi, Jianping Yin, Christine S. Huang, Paul Carter, Diego Ellerman, Benjamin T. Walters, Jiansheng Wu
Publikováno v:
mAbs
Some antibodies exhibit elevated viscosity at high concentrations, making them poorly suited for therapeutic applications requiring administration by injection such as subcutaneous or ocular delivery. Here we studied an anti-IL-13/IL-17 bispecific Ig
Autor:
Joshua D. Webster, Vishva M. Dixit, Christine S. Huang, Merone Roose-Girma, Wendy Sandoval, Søren Warming, Andrew Birnberg, Qingling Li, Yue Zhang, László G. Kőműves, Kim Newton, Rohit Reja, Kebing Yu, Nina Oberbeck, Weng Wong, Allie Maltzman, Victoria Pham, Debra L. Dugger
Publikováno v:
Nature. 574(7777)
The integrity of the mammalian epidermis depends on a balance of proliferation and differentiation in the resident population of stem cells1. The kinase RIPK4 and the transcription factor IRF6 are mutated in severe developmental syndromes in humans,
Autor:
Annie M. Dosey, Mathilde Foglierini, Jessica Marcandalli, Nadia Martinez-Martin, Antonio Lanzavecchia, Laurent Perez, Hoangdung Ho, Christine S. Huang, Claudio Ciferri, Stephanie Shriver, Christopher P. Arthur, Michela Perotti, Jian Payandeh, Alexander Leitner
Publikováno v:
Cell. 174(5)
Characterizing cell surface receptors mediating viral infection is critical for understanding viral tropism and developing antiviral therapies. Nevertheless, due to challenges associated with detecting protein interactions on the cell surface, the ho
Autor:
Evan Healy, Raphaël Margueron, Aoife McLysaght, Haruhiko Koseki, Luciano Di Croce, Darren J. Fitzpatrick, Emilia Jerman, Orla Deevy, Manabu Nakayama, Kieran Wynne, Giorgio Oliviero, Gundula Streubel, Karsten Hokamp, Adrian P. Bracken, Claudio Ciferri, Ariane Watson, Indigo Pratt-Kelly, Christine S. Huang, Paul Chammas, Marlena Mucha, Tomoyuki Ishikura, Eleanor Glancy, Gerard Cagney, Eric Conway, Shinsuke Ito, Alan M. Rice, Daniel Holoch, Yoko Koseki
Publikováno v:
Molecular cell. 70(3)
Summary The polycomb repressive complex 2 (PRC2) consists of core subunits SUZ12, EED, RBBP4/7, and EZH1/2 and is responsible for mono-, di-, and tri-methylation of lysine 27 on histone H3. Whereas two distinct forms exist, PRC2.1 (containing one pol
Autor:
Nianhui, Zhang, Zechun, Peng, Xiaoping, Tong, A Kerstin, Lindemeyer, Yliana, Cetina, Christine S, Huang, Richard W, Olsen, Thomas S, Otis, Carolyn R, Houser
Publikováno v:
Experimental neurology. 297
While numerous changes in the GABA system have been identified in models of Fragile X Syndrome (FXS), alterations in subunits of the GABAA receptors (GABAARs) that mediate tonic inhibition are particularly intriguing. Considering the key role of toni
Publikováno v:
Nature communications, vol 6, iss 1
Nature Communications
Nature Communications
Geranyl-CoA carboxylase (GCC) is essential for the growth of Pseudomonas organisms with geranic acid as the sole carbon source. GCC has the same domain organization and shares strong sequence conservation with the related biotin-dependent carboxylase
Publikováno v:
Nature, vol 481, iss 7380
3-Methylcrotonyl-CoA carboxylase (MCC), a member of the biotin-dependent carboxylase superfamily, is essential for the metabolism of leucine, and deficient mutations in this enzyme are linked to methylcrotonylglycinuria (MCG) and other serious diseas