Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Christine Rudy"'
Autor:
Uta Erdbruegger, Natalie Z Eichner, Nicole M Gilbertson, Christine Rudy, Luca Musante, Steven K Malin, Thu H Le
Publikováno v:
Hypertension. 70
Hypertension (HTN) is a leading cause of cardiovascular disease. Early and non-invasive biomarkers of vascular dysfunction and end-organ damage in HTN are needed to optimize treatment for patients at risk for HTN. Extracellular vesicles (EVs) are pot
Publikováno v:
Hypertension. 68
Despite the significant deleterious impact of hypertension (HTN), the blood pressure (BP) threshold at which to treat remains a matter of debate. Early and non-invasive biomarkers of end-organ damage in HTN are needed to optimize treatment for patien
Publikováno v:
Hypertension. 66
Background: Early and non-invasive biomarkers of kidney damage are needed to identify hypertensive patients at risk for kidney damage. Urinary micropaticles (UMPs) have gained significant attention as potential novel biomarkers for kidney damage, and
Publikováno v:
Hypertension. 64
Introduction: We previously reported a locus on mouse chromosome 11 (chrom 11) linked to development of hypertension (HTN) after sub-total nephrectomy (Nx). To begin fine mapping, we used the 129S6 (129) susceptible strain and the C57BL/6 (B6) resist
Publikováno v:
Hypertension. 64
Background: Hypertension (HTN) is a leading risk factor of cardiovascular diseases. Its pathogenesis is poorly understood, but activation of the renin angiotensin system is thought to be a key event. Vascular damage is an early manifestation of HTN.
Publikováno v:
The Journal of Experimental Medicine
Mls-1 is an endogenous superantigen that leads to in vivo deletion and in vitro stimulation of T cell receptor (TCR) V beta 6-, 7-, 8.1-, and 9-expressing cells. The MA/MyJ mouse deletes the identical set of TCR from its mature T cell repertoire; how
Publikováno v:
International Reviews of Immunology. 8:279-288
Recently a series of endogenous and exogenous superantigens have been described which have one common feature, namely, they lead to in vivo deletion and in vitro stimulation of T cells expressing particular T cell receptor V beta genes. The Mls antig
Publikováno v:
Nature. 349:526-528
T CELLS that recognize self antigen are clonally deleted in the thymus—a maturation process that occurs in the context of histo-compatibility molecules and the T-cell receptor. The minor lymphocyte stimulation antigens (Mis) effect these deletions
Publikováno v:
Blood. 55:811-816
A 72-yr-old male with a lifelong history of easy bruisability and posttraumatic bleeding had a prolonged prothrombin time and activated partial thromboplastin time. His plasma Stypven, Taipan, and Echis carinatus venom clotting times were prolonged.
Publikováno v:
American Journal of Hematology. 9:237-248
A 38-year-old male patient with a life-long history of easy bruising and mild bleeding had a prolonged activated partial thromboplastin time (APTT), prothrombin time (PT), and thrombin time (TT). Reptilase (Bathrops atrox) clotting time was normal. H