Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Christine Rizzo"'
Autor:
Huifeng Niu, David Heimbrook, Aruna Railkar, Jia Kui Li, Harpreet K. Sandhu, Petra Goelzer, Mei Liu, Nader Fotouhi, Nicholas Huby, John Moliterni, Christine Rizzo, Huisheng Wang, Kathryn Packman, Kenneth Kolinsky, Brian Higgins, Sherif Daouti
Supplementary Figures 1-2 from Preclinical In vivo Evaluation of Efficacy, Pharmacokinetics, and Pharmacodynamics of a Novel MEK1/2 Kinase Inhibitor RO5068760 in Multiple Tumor Models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b27a81b81845d3a1a9eea544506caaef
https://doi.org/10.1158/1535-7163.22484477.v1
https://doi.org/10.1158/1535-7163.22484477.v1
Autor:
Huifeng Niu, David Heimbrook, Aruna Railkar, Jia Kui Li, Harpreet K. Sandhu, Petra Goelzer, Mei Liu, Nader Fotouhi, Nicholas Huby, John Moliterni, Christine Rizzo, Huisheng Wang, Kathryn Packman, Kenneth Kolinsky, Brian Higgins, Sherif Daouti
Targeting the Ras/Raf/mitogen-activated protein kinase kinase (MEK)/extracellular signal-regulated kinase (ERK) pathway represents a promising anticancer strategy. Recently, we have reported a novel class of potent and selective non–ATP-competitive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48f11847fc95e122e6d967121d5c49bd
https://doi.org/10.1158/1535-7163.c.6531425.v1
https://doi.org/10.1158/1535-7163.c.6531425.v1
Autor:
Huifeng Niu, David Heimbrook, John F. Boylan, Neal Rosen, Kathryn Packman, Brian Higgins, Christine Rizzo, Yang Wen, Wen-hui Li, Sherif Daouti, Huisheng Wang
Supplementary Figure Legends 1-2 from Identification of the MEK1(F129L) Activating Mutation as a Potential Mechanism of Acquired Resistance to MEK Inhibition in Human Cancers Carrying the B-RafV600E Mutation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f10e8e565bd522991f16622603f03ed
https://doi.org/10.1158/0008-5472.22387878
https://doi.org/10.1158/0008-5472.22387878
Autor:
Huifeng Niu, David Heimbrook, John F. Boylan, Neal Rosen, Kathryn Packman, Brian Higgins, Christine Rizzo, Yang Wen, Wen-hui Li, Sherif Daouti, Huisheng Wang
Supplementary Figures 1-2 from Identification of the MEK1(F129L) Activating Mutation as a Potential Mechanism of Acquired Resistance to MEK Inhibition in Human Cancers Carrying the B-RafV600E Mutation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8b0147158c6c1c7beba421085b354dd
https://doi.org/10.1158/0008-5472.22387875.v1
https://doi.org/10.1158/0008-5472.22387875.v1
Autor:
Amina Belcaid, Christine Rizzo, Gilles Bourgeois, Lynne Moore, Abakar Idriss-Hassan, Kahina Soltana, Jaimini Thakore, Julien Clément, Mélanie Bérubé, Xavier Neveu
Publikováno v:
European Journal of Trauma and Emergency Surgery. 48:1351-1361
Approximately, one out of five patients hospitalized following injury will develop at least one hospital complication, more than three times that observed for general admissions. We currently lack actionable Quality Indicators (QI) targeting specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f0885ca8bb84949b0fdbc3696981f85
https://doi.org/10.1007/s00068-021-01681-5
https://doi.org/10.1007/s00068-021-01681-5
Autor:
Christine Rizzo
Publikováno v:
Journal of Marital and Family Therapy. 46:740-741
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f082cc267efe0f1270ddc63cf3689c3d
https://doi.org/10.1111/jmft.12430
https://doi.org/10.1111/jmft.12430
Autor:
Huisheng Wang, Christine Rizzo, Neal Rosen, Brian Higgins, Huifeng Niu, Sherif Daouti, Yang Wen, Wen-hui Li, David C. Heimbrook, Packman Kathryn E, Boylan John Frederick
Publikováno v:
Cancer Research. 71:5535-5545
Although targeting the Ras/Raf/MEK pathway remains a promising anticancer strategy, mitogen-activated protein/extracellular signal-regulated kinase (ERK) kinase (MEK) inhibitors in clinical development are likely to be limited in their ability to pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::655f034c22fb537391ef3b8d1bd645e7
https://doi.org/10.1158/0008-5472.can-10-4351
https://doi.org/10.1158/0008-5472.can-10-4351
Autor:
Melissa Smith, Wei He, Brian Higgins, Xuefeng Yin, Leopoldo Luistro, Packman Kathryn E, John Frederick Boylan, David C. Heimbrook, Daisy Carvajal, James Cai, Christine Rizzo, Tom Nevins, Kenneth Kolinsky
Publikováno v:
Molecular oncology. 5(3)
Interest continues to build around the early application of patient selection markers to prospectively identify patients likely to show clinical benefit from cancer therapies. Hypothesis generation and clinical strategies often begin at the preclinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7d13566e38df0283a413ceefb697a83
https://pubmed.ncbi.nlm.nih.gov/21315665
https://pubmed.ncbi.nlm.nih.gov/21315665
Autor:
Huifeng Niu, Brian Higgins, Kenneth Kolinsky, Huisheng Wang, Jia Kui Li, Sherif Daouti, Harpreet K. Sandhu, Petra Goelzer, David C. Heimbrook, Mei Liu, Packman Kathryn E, Aruna Railkar, Nader Fotouhi, John Anthony Moliterni, Nicholas John Silvester Huby, Christine Rizzo
Publikováno v:
Molecular cancer therapeutics. 9(1)
Targeting the Ras/Raf/mitogen-activated protein kinase kinase (MEK)/extracellular signal-regulated kinase (ERK) pathway represents a promising anticancer strategy. Recently, we have reported a novel class of potent and selective non–ATP-competitive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a10022a43f230d2596f5b4e8f29b8ef
https://pubmed.ncbi.nlm.nih.gov/20053779
https://pubmed.ncbi.nlm.nih.gov/20053779
Autor:
Wen-hui Li, Sherif Daouti, Christine Rizzo, Neal Rosen, Brian Higgins, Huisheng Wang, John Frederick Boylan, Yang Wen, Packman Kathryn E, Huifeng Niu, David C. Heimbrook
Publikováno v:
Cancer Research. 71:5036-5036
Targeting the Ras/Raf/MEK pathway represents a promising anticancer strategy. The clinical development of MEK inhibitors, similar to other highly selective targeted agents, is expected to have limited durable clinical response due to the emergence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edc3d4938e0112e00aa687691e13685d
https://doi.org/10.1158/1538-7445.am2011-5036
https://doi.org/10.1158/1538-7445.am2011-5036