Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Christine Rasetti-Escargueil"'
Publikováno v:
Toxins, Vol 16, Iss 6, p 261 (2024)
Botulinum neurotoxins (BoNTs) have been used for almost half a century in the treatment of excessive muscle contractility. BoNTs are routinely used to treat movement disorders such as cervical dystonia, spastic conditions, blepharospasm, and hyperhid
Externí odkaz:
https://doaj.org/article/f225cadd96344ff983c24ba2a7d597db
Publikováno v:
Toxins, Vol 15, Iss 2, p 100 (2023)
Ricin toxin is a disulfide-linked glycoprotein (AB toxin) comprising one enzymatic A chain (RTA) and one cell-binding B chain (RTB) contained in the castor bean, a Ricinus species. Ricin inhibits peptide chain elongation via disruption of the binding
Externí odkaz:
https://doaj.org/article/7becd5139b1f40649ad1f26a751f9b15
Autor:
Grazia Cottone, Letizia Chiodo, Luca Maragliano, Michel-Robert Popoff, Christine Rasetti-Escargueil, Emmanuel Lemichez, Thérèse E. Malliavin
Publikováno v:
Toxins, Vol 14, Iss 9, p 644 (2022)
Although botulinum neurotoxins (BoNTs) are among the most toxic compounds found in nature, their molecular mechanism of action is far from being elucidated. A key event is the conformational transition due to acidification of the interior of synaptic
Externí odkaz:
https://doaj.org/article/8c182d48258645a7a88e64d3ad8d07ce
Publikováno v:
Microorganisms, Vol 10, Iss 5, p 1001 (2022)
Botulinum neurotoxins (BoNTs) are produced as protein complexes by bacteria of the genus Clostridium that are Gram-positive, anaerobic and spore forming (Clostridium botulinum, C. butyricum, C. baratii and C. argentinense spp.). BoNTs show a high imm
Externí odkaz:
https://doaj.org/article/91c0a77b7a04496c98ad3ef62e473eaf
Publikováno v:
Toxins, Vol 13, Iss 1, p 1 (2020)
Botulinum neurotoxins (BoNTs) show increasing therapeutic applications ranging from treatment of locally paralyzed muscles to cosmetic benefits. At first, in the 1970s, BoNT was used for the treatment of strabismus, however, nowadays, BoNT has multip
Externí odkaz:
https://doaj.org/article/7d6d597ab87d43ae96153f3e0d7f71a7
Publikováno v:
Toxins, Vol 12, Iss 11, p 716 (2020)
Human botulism is a severe disease characterized by flaccid paralysis and inhibition of certain gland secretions, notably salivary secretions, caused by inhibition of neurotransmitter release. Naturally acquired botulism occurs in three main forms: f
Externí odkaz:
https://doaj.org/article/9d5c7f6fbe1b4fad9dc3179fe1c2dbd9
Publikováno v:
Toxins, Vol 12, Iss 5, p 338 (2020)
Botulism is a rare but severe disease which is characterized by paralysis and inhibition of secretions. Only a few cases had been reported at the end of the 19th century in France. The disease was frequent during the second world war, and then the in
Externí odkaz:
https://doaj.org/article/4ef2fc4a42894c3d92d97426a54ab040
Publikováno v:
Toxins, Vol 12, Iss 1, p 17 (2019)
Botulism is a rare but severe neurological disease in man and animals that is caused by botulinum neurotoxins (BoNTs) produced by Clostridium botulinum and atypical strains from other Clostridium and non-Clostridium species. BoNTs are divided into mo
Externí odkaz:
https://doaj.org/article/2fdc5d8d4233429db4fd15ad4218e703
Publikováno v:
Toxins, Vol 11, Iss 9, p 528 (2019)
Botulinum neurotoxin (BoNT) is produced by the anaerobic, Gram-positive bacterium Clostridium botulinum. As one of the most poisonous toxins known and a potential bioterrosism agent, BoNT is characterized by a complex mode of action comprising: inter
Externí odkaz:
https://doaj.org/article/1f98ec29e15a45e7960e8356a6a690fd
Autor:
Sebastian Miethe, Christelle Mazuet, Yvonne Liu, Robert Tierney, Christine Rasetti-Escargueil, Arnaud Avril, André Frenzel, Philippe Thullier, Thibaut Pelat, Remi Urbain, Alexandre Fontayne, Dorothea Sesardic, Michael Hust, Michel Robert Popoff
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161446 (2016)
Botulinum neurotoxins (BoNTs) are counted among the most toxic substances known and are responsible for human botulism, a life-threatening disease characterized by flaccid muscle paralysis that occurs naturally by food poisoning or colonization of th
Externí odkaz:
https://doaj.org/article/3dfe8169d86e47538b9d3a846c6718a2