Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Christine R. Carlisle"'
Autor:
Christine R. Carlisle, Justin Sigley, Keith Bonin, Stephen R. Baker, Martin Guthold, Joel D. Stitzel, Joel L. Berry
Publikováno v:
Materials Science and Engineering: C. 32:215-221
Due to their low immunogenicity, biodegradability and native cell-binding domains, fibrinogen fibers may be good candidates for tissue engineering scaffolds, drug delivery vehicles and other medical devices. We used a combined atomic force microscope
Autor:
Roy R. Hantgan, Martin Guthold, David L. Carroll, Christine R. Carlisle, Corentin Coulais, Manoj A. G. Namboothiry
Publikováno v:
Biomaterials. 30:1205-1213
We used a combined atomic force microscopic (AFM)/fluorescence microscopic technique to study the mechanical properties of individual, electrospun fibrinogen fibers in aqueous buffer. Fibers (average diameter 208 nm) were suspended over 12 microm-wid
Autor:
Martin Guthold, Roy R. Hantgan, Susan T. Lord, Richard Superfine, Michael R. Falvo, E. A. Sparks, Wenhua Liu, Christine R. Carlisle
Publikováno v:
Journal of Thrombosis and Haemostasis. 5:P-W
Publikováno v:
Microscopy research and technique. 74(3)
Deep ultraviolet (DUV) microscopy is a fluorescence microscopy technique to image unlabeled proteins via the native fluorescence of some of their amino acids. We constructed a DUV fluorescence microscope, capable of 280 nm wavelength excitation by mo
Publikováno v:
Journal of thrombosis and haemostasis : JTH. 8(5)
Blood clots perform the mechanical task of stemming the flow of blood.To advance understanding and realistic modeling of blood clot behavior we determined the mechanical properties of the major structural component of blood clots, fibrin fibers.We us
Autor:
Martin Guthold, Justin Sigley, Joel D. Stitzel, Joel L. Berry, Keith Bonin, Stephen R. Baker, Christine R. Carlisle
Publikováno v:
ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology.
Understanding the material properties of the nanofibers comprising electrospun scaffolds for tissue engineering will elucidate the mechanotransduction of cells seeded onto and attached those scaffolds. The overall mechanical properties of any structu
Publikováno v:
Acta Biomater
Knowledge of the mechanical properties of electrospun fibers is important for their successful application in tissue engineering, material composites, filtration and drug delivery. In particular, electrospun collagen has great potential for biomedica
Autor:
Martin Guthold, Christine R. Carlisle
Publikováno v:
Journal of Thrombosis and Haemostasis. 8:2090-2091
Autor:
Janet S. Lee, Ryan Vest, Christine R. Carlisle, Mark T. Gladwin, Mary C. Stahle, Roy R. Hantgan, Daniel B. Kim-Shapiro
Publikováno v:
Blood. 118:5262-5262
Abstract 5262 Nitric oxide (NO) has been previously shown to inhibit adenosine diphosphate (ADP)- and thrombin- mediated platelet activation. This inhibitory effect of NO is blocked by cell-free oxyhemoglobin (Villagra, Shiva et al. 2007). Cell-free
Publikováno v:
Biophysical Journal. (3):192a
Blood clots have the mechanical task of stemming blood flow; yet despite decades of work our understanding of the mechanical properties of blood clots is still poor. In fact, currently there is no good mechanical model of a blood clot available. One