Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Christine R Swanson"'
Autor:
Marijan Posavi, Maria Diaz-Ortiz, Benjamine Liu, Christine R Swanson, R Tyler Skrinak, Pilar Hernandez-Con, Defne A Amado, Michelle Fullard, Jacqueline Rick, Andrew Siderowf, Daniel Weintraub, Leo McCluskey, John Q Trojanowski, Richard B Dewey, Xuemei Huang, Alice S Chen-Plotkin
Publikováno v:
PLoS Medicine, Vol 16, Iss 10, p e1002931 (2019)
BackgroundParkinson's disease (PD) is a progressive neurodegenerative disease affecting about 5 million people worldwide with no disease-modifying therapies. We sought blood-based biomarkers in order to provide molecular characterization of individua
Externí odkaz:
https://doaj.org/article/3caac71e01d044348e561772c1e33946
Autor:
Sachiko Ohshima-Hosoyama, Heather A Simmons, Nichole Goecks, Valerie Joers, Christine R Swanson, Viktoriya Bondarenko, Rebecca Velotta, Kevin Brunner, Laura D Wood, Ralph H Hruban, Marina E Emborg
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39036 (2012)
Glial cell line derived neurotrophic factor (GDNF) is a neurotrophic factor that has neuroprotective effects in animal models of Parkinson's disease (PD) and has been proposed as a PD therapy. GDNF does not cross the blood brain barrier (BBB), and re
Externí odkaz:
https://doaj.org/article/e81c51243a0f4f3e8cf62a64d9a20f6a
Autor:
Leo McCluskey, Pilar Hernandez-Con, Xuemei Huang, Defne A. Amado, Michelle E. Fullard, Richard B. Dewey, Marijan Posavi, John Q. Trojanowski, Maria Diaz-Ortiz, Benjamine Liu, Daniel Weintraub, Andrew Siderowf, Jacqueline Rick, Alice Chen-Plotkin, Christine R. Swanson, R. Tyler Skrinak
Publikováno v:
PLoS Medicine, Vol 16, Iss 10, p e1002931 (2019)
PLoS Medicine
PLoS Medicine
Background Parkinson’s disease (PD) is a progressive neurodegenerative disease affecting about 5 million people worldwide with no disease-modifying therapies. We sought blood-based biomarkers in order to provide molecular characterization of indivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7345af0cde28954270655b2a24617b74
https://doaj.org/article/3caac71e01d044348e561772c1e33946
https://doaj.org/article/3caac71e01d044348e561772c1e33946
Autor:
Alice Chen-Plotkin, Christine R. Swanson, Lama M. Chahine, Roy N. Alcalay, Sharon X. Xie, Yosef Berlyand
Publikováno v:
Movement Disorders. 30:1648-1656
Background: Development of robust plasma-based biomarkers in Parkinson's disease (PD) could lead to new approaches for identifying those at risk for PD and developing novel therapies. Here, we validate plasma apolipoprotein A1 (ApoA1) as a correlate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::848bcef0ae107f8bd6f5fd4d74895d66
https://doi.org/10.1002/mds.26290
https://doi.org/10.1002/mds.26290
Autor:
Ali Samii, John Q. Trojanowski, Christine R. Swanson, John W. Roberts, Rachel Goldmann Gross, Pinky Agarwal, Howard I. Hurtig, Kathy Li, Travis L. Unger, Daniel Weintraub, Michael D. Gallagher, Jacqueline Rick, Alice Chen-Plotkin, Cyrus P. Zabetian, Vivianna M. Van Deerlin, James B. Leverenz
Publikováno v:
Movement Disorders. 30:805-812
The discovery of novel plasma-based biomarkers could lead to new approaches in the treatment of Parkinson's disease (PD). Here, we explore the role of plasma apolipoprotein A1 (ApoA1) as a risk marker for PD and evaluate the influence of APOA1 promot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9968c5e290cb20aca740584f7194833
https://doi.org/10.1002/mds.26022
https://doi.org/10.1002/mds.26022
Autor:
Christine R. Swanson, Marina E. Emborg
Publikováno v:
Neurological Research. 36:634-646
To characterize the distribution of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) in the substantia nigra of normal and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated hemiparkinsonian monkeys, in order to validate PPAR-ga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5736faf91a81ed30f2b632184eda13b8
https://doi.org/10.1179/1743132813y.0000000305
https://doi.org/10.1179/1743132813y.0000000305
Autor:
Sharon X. Xie, Ken Marek, John Q. Trojanowski, Andrew Siderowf, Christine R. Swanson, Travis L. Unger, Daniel Weintraub, Hua‐Ren Cherng, Matthew B. Stern, Alice Chen-Plotkin, Nicholas Lim
Publikováno v:
Annals of Clinical and Translational Neurology
Objective Cognitive decline occurs in multiple neurodegenerative diseases, including Alzheimer's disease (AD) and Parkinson's disease (PD). Shared underlying mechanisms may exist and manifest as shared biomarker signatures. Previously, we nominated p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd68f74f2372410f5a468ccfe3ebafed
https://pubmed.ncbi.nlm.nih.gov/27231704
https://pubmed.ncbi.nlm.nih.gov/27231704
Autor:
Christine R, Swanson, Katherine, Li, Travis L, Unger, Michael D, Gallagher, Vivianna M, Van Deerlin, Pinky, Agarwal, James, Leverenz, John, Roberts, Ali, Samii, Rachel Goldmann, Gross, Howard, Hurtig, Jacqueline, Rick, Daniel, Weintraub, John Q, Trojanowski, Cyrus, Zabetian, Alice S, Chen-Plotkin
Publikováno v:
Movement disorders : official journal of the Movement Disorder Society. 30(6)
The discovery of novel plasma-based biomarkers could lead to new approaches in the treatment of Parkinson's disease (PD). Here, we explore the role of plasma apolipoprotein A1 (ApoA1) as a risk marker for PD and evaluate the influence of APOA1 promot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::96b695c221cf5e85aef78a7b8ea91c20
https://pubmed.ncbi.nlm.nih.gov/25227208
https://pubmed.ncbi.nlm.nih.gov/25227208
Autor:
Kyle Cummisford, Do P.M. Tromp, Marc Sonnemans, Bas Blits, Christine R. Swanson, Viktorya Bondarenko, Marina E. Emborg, Valerie Joers, Samuel A. Hurley, Stephan Hermening, Andrew L. Alexander, Sachiko Ohshima-Hosoyama
Publikováno v:
Stereotactic and functional neurosurgery. 92(3)
Background: The efficacy and safety of intracerebral gene therapy for brain disorders like Parkinson's disease depends on the appropriate distribution of gene expression. Objectives: To assess whether the distribution of gene expression is affected b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ebaecbdd4e30cdb72e57c33feb3eb4c
https://pubmed.ncbi.nlm.nih.gov/24943657
https://pubmed.ncbi.nlm.nih.gov/24943657
Publikováno v:
PPAR Research
PPAR Research, Vol 2013 (2013)
PPAR Research, Vol 2013 (2013)
Activation of the peroxisome proliferator activated receptor-gamma (PPAR)-γis proposed as a neuroprotective strategy to treat neurodegenerative disorders. In this study, we examined if LSN862 (LSN), a novel non-thiazoledinedione partial PPAR-γagoni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f8b416549f0a54ac9dc97c457572541