Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Christine Rösler"'
Autor:
Markus Gajer, Katharina Dörnbrack, Christine Rösler, Bernadette Schmid, Jürgen Beck, Michael Nassal
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract Hepadnaviruses, including human hepatitis B virus (HBV), replicate their tiny DNA genomes by protein-primed reverse transcription of a pregenomic (pg) RNA. Replication initiation as well as pgRNA encapsidation depend on the interaction of th
Externí odkaz:
https://doaj.org/article/7431dee15fa947bb97373f7fe4a05b75
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37248 (2012)
Experimental studies on hepatitis B virus (HBV) replication are commonly done with human hepatoma cells to reflect the natural species and tissue tropism of the virus. However, HBV can also replicate, upon transfection of virus coding plasmids, in ce
Externí odkaz:
https://doaj.org/article/5ab1379add0b41229a16d790574a0be3
Autor:
Josef Köck, Christine Rösler, Jing-Jing Zhang, Hubert E Blum, Michael Nassal, Christian Thoma
Publikováno v:
PLoS Pathogens, Vol 6, Iss 9, p e1001082 (2010)
Persistence of hepatitis B virus (HBV) infection requires covalently closed circular (ccc)DNA formation and amplification, which can occur via intracellular recycling of the viral polymerase-linked relaxed circular (rc) DNA genomes present in virions
Externí odkaz:
https://doaj.org/article/314c024ff3a542359c6ccb05ec32ba6b
Publikováno v:
Journal of Virology. 85:9300-9313
In all hepadnaviruses, protein-primed reverse transcription of the pregenomic RNA (pgRNA) is initiated by binding of the viral polymerase, P protein, to the ε RNA element. Universally, ε consists of a lower stem and an upper stem, separated by a bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ebc18e3ba6f59c17786130c753b882
https://doi.org/10.1128/jvi.05005-11
https://doi.org/10.1128/jvi.05005-11
Autor:
Moritz Marsmann, Jürgen Beck, Christian Königer, Christine Rösler, Michael Nassal, Ida Wingert
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 111(40)
Hepatitis B virus (HBV), the causative agent of chronic hepatitis B and prototypic hepadnavirus, is a small DNA virus that replicates by protein-primed reverse transcription. The product is a 3-kb relaxed circular DNA (RC-DNA) in which one strand is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39349ca836156201a7471d0fdb601896
https://pubmed.ncbi.nlm.nih.gov/25201958
https://pubmed.ncbi.nlm.nih.gov/25201958
Publikováno v:
Journal of hepatology. 52(6)
Background & Aims RNA interference (RNAi) may offer new treatment options for chronic hepatitis B. Replicating via an RNA intermediate, hepatitis B virus (HBV) is known to be principally vulnerable to RNAi. However, beyond delivery, the relevant issu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57fc7a33fb2efbc2fd9fac81724ca2c6
https://pubmed.ncbi.nlm.nih.gov/20400195
https://pubmed.ncbi.nlm.nih.gov/20400195
Publikováno v:
Hepatology (Baltimore, Md.). 46(3)
APOBEC3G (A3G) and APOBEC3C (A3C), 2 members of the APOBEC family, are cellular cytidine deaminases displaying broad antiretroviral activity. A3G inhibits hepatitis B virus (HBV) production by interfering with HBV replication without hypermutating th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a6a8d3f81930d0e703662fac6197739
https://pubmed.ncbi.nlm.nih.gov/17625792
https://pubmed.ncbi.nlm.nih.gov/17625792
Autor:
Christine Rösler, Josef Köck, Michael Kann, Hubert E. Blum, Fritz von Weizsäcker, Michael H. Malim, Thomas Baumert
Publikováno v:
Hepatology (Baltimore, Md.). 42(2)
APOBEC3G is a cellular cytidine deaminase displaying broad antiretroviral activity. Recently, it was shown that APOBEC3G can also suppress hepatitis B virus (HBV) production in human hepatoma cells. In the present study, we characterized the mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1de58c353734102508c75896e42fa29
https://pubmed.ncbi.nlm.nih.gov/16025511
https://pubmed.ncbi.nlm.nih.gov/16025511
Publikováno v:
Cardiovascular research. 40(3)
Objective: In the recent past it has become clear that the kallikrein–kinin system is closely intertwined with long-term blood pressure regulation. It was shown that a kinin B2 receptor blockade leads to a sodium-dependent rise in blood pressure. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e39ea567fc1bc85b9faf845fb3895c1
https://pubmed.ncbi.nlm.nih.gov/10070499
https://pubmed.ncbi.nlm.nih.gov/10070499
Publikováno v:
Scopus-Elsevier
The cytidine deaminase APOBEC3G (A3G) was recently identified as a natural resistance gene that restricts efficient propagation of human immunodeficiency virus and other retroviruses. The enzyme induces massive cytidine to uridine (C→ U) deaminatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce052641d96c63ef03281c5c34e35c17
http://www.scopus.com/inward/record.url?eid=2-s2.0-4644241324&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-4644241324&partnerID=MN8TOARS
