BAT3 modulates p300-dependent acetylation of p53 and autophagy-related protein 7 (ATG7) during autophagy

Autor: Laetitia K. Linares, Andrew V. Hubberstey, Emmanuelle Liaudet-Coopman, Nelly Pirot, Fabienne Desmots, Guy Berchem, Anne-Sophie Bach, Esther Pérez-Gracia, Christine Prébois, Valérie Palissot, Patrice Codogno, Céline Gongora, Salwa Sebti, Sophie Pattingre, Chantal Bauvy

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2014, 111 (11), pp.4115-20. 〈10.1073/pnas.1313618111〉
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2014, 111 (11), pp.4115-20. ⟨10.1073/pnas.1313618111⟩
Proceedings of the National Academy of Sciences of the United States of America, 2014, 111 (11), pp.4115-20. ⟨10.1073/pnas.1313618111⟩
Biological Sciences Publications

International audience; Autophagy is regulated by posttranslational modifications, including acetylation. Here we show that HLA-B-associated transcript 3 (BAT3) is essential for basal and starvation-induced autophagy in embryonic day 18.5 BAT3(-/-) m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90cbd9bbdfb06ff6067a9638666a9d10
https://doi.org/10.1073/pnas.1313618111

BAG6/BAT3 modulates autophagy by affecting EP300/p300 intracellular localization

Autor: Guy Berchem, Valeŕie Palissot, Céline Gongora, Salwa Sebti, Laetitia K. Linares, Patrice Codogno, Nelly Pirot, Emmanuelle Liaudet-Coopman, Esther Pérez-Gracia, Sophie Pattingre, Fabienne Desmots, Chantal Bauvy, Anne Sophie Bach, Andrew V. Hubberstey, Christine Prébois

Publikováno v: Autophagy
Autophagy, Taylor & Francis, 2014, 10 (7), pp.1341-1342. ⟨10.4161/auto.28979⟩
Autophagy, Taylor & Francis, 2014, 10 (7), pp.1341--2. ⟨10.4161/auto.28979⟩
Autophagy, 2014, 10 (7), pp.1341--2. ⟨10.4161/auto.28979⟩
Biological Sciences Publications

International audience; We recently reported that BAG6/BAT3 (BCL2-associated athanogene 6) is essential for basal and starvation-induced autophagy in E18.5 bag6(-/-) mouse embryos and in mouse embryonic fibroblasts (MEFs) through the modulation of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fb112c0207cedcc4b7d8637e3f50229
https://pubmed.ncbi.nlm.nih.gov/24852146

Cathepsin D is partly endocytosed by the LRP1 receptor and inhibits LRP1-regulated intramembrane proteolysis.: Cathepsin D, endocytosis and LRP1 RIP

Autor: Emmanuelle Liaudet-Coopman, Gary K. Smith, Mélanie Beaujouin, Sophie Pattingre, Danielle Derocq, Laurent-Matha, Christine Prébois

Publikováno v: Oncogene
Oncogene, Nature Publishing Group, 2012, 31 (26), pp.3202-12. ⟨10.1038/onc.2011.501⟩

International audience; The aspartic protease cathepsin-D (cath-D) is a marker of poor prognosis in breast cancer that is overexpressed and hypersecreted by human breast cancer cells. Secreted pro-cath-D binds to the extracellular domain of the β-ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::087d1cb782318898918fbc8c0091c2d6
https://www.hal.inserm.fr/inserm-00646373/file/Figure1_13_RIP-1.pdf

Pro-cathepsin D interacts with the extracellular domain of the {beta} chain of LRP1 and promotes LRP1-dependent fibroblast outgrowth

Autor: Bradley T. Hyman, Valérie Laurent-Matha, Danielle Derocq, Gary K. Smith, Hongyu Zhang, Jami B. Grossfield, Emmanuelle Liaudet-Coopman, Zemin Yao, Christine Prébois, Robert E. Hollingsworth, Nadir Bettache, Peter van der Geer, Sophie Pattingre, Olivier Masson, Peter Coopman, Mélanie Beaujouin

Publikováno v: Journal of Cell Science
Journal of Cell Science, Company of Biologists, 2010, 123 (19), pp.3336-3346. ⟨10.1242/jcs.070938⟩

International audience; Interactions between cancer cells and fibroblasts are crucial in cancer progression. We have previously shown that the aspartic protease cathepsin D (cath-D), a marker of poor prognosis in breast cancer that is overexpressed a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::922159aaaab69bf3b29e6f84a32ce59f
https://www.hal.inserm.fr/inserm-00518213/file/Fig5_JCS_3.pdf

Cathepsin D: newly discovered functions of a long-standing aspartic protease in cancer and apoptosis

Autor: Emmanuelle Liaudet-Coopman, Christine Prébois, Mélanie Beaujouin, Henri Rochefort, Valérie Laurent-Matha, Marcel Garcia, Danielle Derocq, Françoise Vignon, Murielle Glondu-Lassis

Publikováno v: Cancer Letters
Cancer Letters, Elsevier, 2006, 237 (2), pp.167-79. ⟨10.1016/j.canlet.2005.06.007⟩

The lysosomal aspartic protease cathepsin D (cath-D) is over-expressed and hyper-secreted by epithelial breast cancer cells. This protease is an independent marker of poor prognosis in breast cancer being correlated with the incidence of clinical met

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f42bd771918e207eab6746ddd9f12c
https://pubmed.ncbi.nlm.nih.gov/16046058