Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Christine Pich"'
Autor:
Laura Yerly, Christine Pich-Bavastro, Jeremy Di Domizio, Tania Wyss, Stéphanie Tissot-Renaud, Michael Cangkrama, Michel Gilliet, Sabine Werner, François Kuonen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The role of reciprocal tumour-stroma interactions in tumour invasion remains poorly characterised. Here, single-cell and spatial transcriptomics identifies the cell populations and their transcriptional reprogramming contributing to the spatial organ
Externí odkaz:
https://doaj.org/article/ea3f55ef4f1f4bc89b960a13a7cc8b39
Autor:
Hyun-Sook Park, Eirini Papanastasi, Gabriela Blanchard, Elena Chiticariu, Daniel Bachmann, Markus Plomann, Fanny Morice-Picard, Pierre Vabres, Asma Smahi, Marcel Huber, Christine Pich, Daniel Hohl
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Park et al. characterise the interactome, localisation and function of Actin-Related Protein-Testis1 protein (ARP-T1), encoded by the ACTRT1 gene, associated with inherited basal cell cancer. They find that ARP-T1 is localised to the primary cilia ba
Externí odkaz:
https://doaj.org/article/a0f02e7c75a741a59d63e638f2446851
Autor:
Patrick Meylan, Christine Pich, Carine Winkler, Stefanie Ginster, Lionel Mury, Marie Sgandurra, René Dreos, Dennie Tompers Frederick, Marc Hammond, Genevieve Marie Boland, Liliane Michalik
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract The thioredoxin system plays key roles in regulating cancer cell malignancy. Here we identify the Thioredoxin-interacting protein (TXNIP) as a gene, which expression is regulated by PPARγ in melanoma cells. We show that high TXNIP expressio
Externí odkaz:
https://doaj.org/article/afba53c8238a4f37922879d894340072
Autor:
Gwendoline Degueurce, Ilenia D'Errico, Christine Pich, Mark Ibberson, Frédéric Schütz, Alexandra Montagner, Marie Sgandurra, Lionel Mury, Paris Jafari, Akash Boda, Julien Meunier, Roger Rezzonico, Nicolò Costantino Brembilla, Daniel Hohl, Antonios Kolios, Günther Hofbauer, Ioannis Xenarios, Liliane Michalik
Publikováno v:
EMBO Molecular Medicine, Vol 8, Iss 8, Pp 919-936 (2016)
Abstract Although excessive exposure to UV is widely recognized as a major factor leading to skin perturbations and cancer, the complex mechanisms underlying inflammatory skin disorders resulting from UV exposure remain incompletely characterized. Th
Externí odkaz:
https://doaj.org/article/9d1b2323a587417db99b476c4952bb43
Autor:
Christine Pich, Iotefa Teiti, Guillaume Sarrabayrouse, Franck Gallardo, Rémi Gence, Anne-Françoise Tilkin-Mariamé
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148095 (2016)
CD70 is a costimulatory molecule member of the Tumor Necrosis Factor family that is expressed on activated immune cells. Its ectopic expression has been described in several types of cancer cells including lymphomas, renal cell carcinomas and gliobla
Externí odkaz:
https://doaj.org/article/9b4c4d44fa3646d18a3f4b3467ea27dd
Autor:
Guillaume Sarrabayrouse, Christine Pich, Raphaël Moriez, Virginie Armand-Labit, Philippe Rochaix, Gilles Favre, Anne-Françoise Tilkin-Mariamé
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9043 (2010)
BACKGROUND: Suboptimal activation of T lymphocytes by melanoma cells is often due to the defective expression of class I major histocompatibility antigens (MHC-I) and costimulatory molecules. We have previously shown that geranylgeranyl transferase i
Externí odkaz:
https://doaj.org/article/046a61634843414f8027d66d54213291
Autor:
Liliane Michalik, Camilla Jandus, Pedro Romero, Mitchell P. Levesque, Jürg Hafner, Christine Goepfert, Catherine Moret, Hélène Moser, Bao Khanh Trang, Romain Loyon, Thanh Nhan Nguyen, Beatris Mastelic-Gavillet, Patrick Meylan, Christine Pich
Three supplementary tables showing: - Characteristics of the melanoma cell lines - Top 10 of significantly upregulated and downregulated genes upon PPARγ specific activation in A375 cells, as quantified by RNA-sequencing - Top 20 of deregulated path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a2030474b0699e13f7b7fcd4b2c3eaa
https://doi.org/10.1158/0008-5472.22420364.v1
https://doi.org/10.1158/0008-5472.22420364.v1
Autor:
Liliane Michalik, Camilla Jandus, Pedro Romero, Mitchell P. Levesque, Jürg Hafner, Christine Goepfert, Catherine Moret, Hélène Moser, Bao Khanh Trang, Romain Loyon, Thanh Nhan Nguyen, Beatris Mastelic-Gavillet, Patrick Meylan, Christine Pich
Supplementary Materials and methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29a65112d577e8164b29f96a095b03d1
https://doi.org/10.1158/0008-5472.22420370
https://doi.org/10.1158/0008-5472.22420370
Autor:
Liliane Michalik, Camilla Jandus, Pedro Romero, Mitchell P. Levesque, Jürg Hafner, Christine Goepfert, Catherine Moret, Hélène Moser, Bao Khanh Trang, Romain Loyon, Thanh Nhan Nguyen, Beatris Mastelic-Gavillet, Patrick Meylan, Christine Pich
Four supplementary figures showing - PPARg activation regulates pro-inflammatory cytokine expression in A375 melanoma cells - Impact of RGZ exposure on the expression of PPARg-target genes and of pro-inflammatory cytokines in a variety of cancer cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea2f6024fe7dca24f7da2b38b9299629
https://doi.org/10.1158/0008-5472.22420367
https://doi.org/10.1158/0008-5472.22420367
Autor:
Liliane Michalik, Camilla Jandus, Pedro Romero, Mitchell P. Levesque, Jürg Hafner, Christine Goepfert, Catherine Moret, Hélène Moser, Bao Khanh Trang, Romain Loyon, Thanh Nhan Nguyen, Beatris Mastelic-Gavillet, Patrick Meylan, Christine Pich
In addition to improving insulin sensitivity in type 2 diabetes, the thiazolidinedione family of compounds and the pharmacologic activation of their best-characterized target PPARγ have been proposed as a therapeutic option for cancer treatment. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1055018ff034c9ddefa468b0bd83606a
https://doi.org/10.1158/0008-5472.c.6510632
https://doi.org/10.1158/0008-5472.c.6510632