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of 26
pro vyhledávání: '"Christine Pesold"'
Autor:
Erminio Costa, John Davis, Dennis R. Grayson, Alessandro Guidotti, George D. Pappas, Christine Pesold
Publikováno v:
Neurobiology of Disease, Vol 8, Iss 5, Pp 723-742 (2001)
In this review, we will first present a brief overview of the current understanding of: (a) the biology of reelin; (b) the putative reelin signaling pathways via integrin receptor stimulation; (c) the cytosolic adapter protein DAB1, which appears to
Externí odkaz:
https://doaj.org/article/e174bd8ea8014b8faf7c7d0d37a0dd6a
Autor:
Miguel A. Rodriguez, Alessandro Guidotti, Erminio Costa, Wen Sheng Liu, Christine Pesold, Hector J. Caruncho
Publikováno v:
The Journal of Comparative Neurology. 451:279-288
In nonhuman and human primates, reelin immunoreactivity is expressed consistently in gamma-aminobutyric acid (GABA)-ergic interneurons of the three upper cortical layers (Impagnatiello et al. [1998] Proc. Natl. Acad. Sci. U S A 95:15718-15723; Rodrig
Publikováno v:
Journal of Neurocytology. 30:413-425
Reelin is a glycoprotein (∼400 kDa) secreted by GABAergic neurons into the extracellular matrix of the neocortex and hippocampus as well as other areas of adult rodent and nonhuman primate brains. Recent findings indicate that the heterozygote reel
Autor:
Miguel A. Rodriguez, Pascal Lacor, Alessandro Guidotti, Christine Pesold, James Auta, Brian G. Condie, Wen Sheng Liu, John Larson, Erminio Costa, G. Carboni
Publikováno v:
Proceedings of the National Academy of Sciences. 98:3477-3482
Heterozygous reeler mice (HRM) haploinsufficient for reelin express ≈50% of the brain reelin content of wild-type mice, but are phenotypically different from both wild-type mice and homozygous reeler mice. They exhibit, ( i ) a down-regulation of g
Autor:
Erminio Costa, Alessandro Guidotti, James Auta, Emanuela Izzo, Christine Pesold, Francesco Impagnatiello
Publikováno v:
Proceedings of the National Academy of Sciences. 98:3483-3488
Protracted administration of diazepam elicits tolerance, whereas discontinuation of treatment results in signs of dependence. Tolerance to the anticonvulsant action of diazepam is present in an early phase (6, 24, and 36 h) but disappears in a late p
Publikováno v:
Neurochemical Research. 25:1207-1218
Reelin (Reln) is expressed in specific GABAergic neurons in layer I and II of neocortex, and is secreted into the extracellular matrix where it surrounds dendrites, spines and neurite arborizations, and binds to integrin receptors located on post-syn
Publikováno v:
Alcoholism: Clinical and Experimental Research. 23:1848-1852
Background : The mesolimbic/mesoeortical dopamine pathway mediates the rewarding effects of ethanol and other drugs of abuse like cocaine and opiates. Dopaminergic neurons of the ventral tegmental area (VTA) arc the cells of origin of the mesolimbic/
Publikováno v:
Proceedings of the National Academy of Sciences. 96:3217-3222
Reelin (Reln) is a protein with some structural analogies with other extracellular matrix proteins that functions in the regulation of neuronal migration during the development of cortical laminated structures. In the cortex of adult animals, Reln is
Autor:
Christine Pesold, Erminio Costa, Ghanshyam N. Pandey, D.P. Uzunov, Yogesh Dwivedi, Neil R. Smalheiser, Rajiv P. Sharma, George D. Pappas, Maria G. Pisu, Alessandro Guidotti, Francesco Impagnatiello, John M. Davis, Hector J. Caruncho, Patricia Tueting
Publikováno v:
Proceedings of the National Academy of Sciences. 95:15718-15723
Postmortem prefrontal cortices (PFC) (Brodmann’s areas 10 and 46), temporal cortices (Brodmann’s area 22), hippocampi, caudate nuclei, and cerebella of schizophrenia patients and their matched nonpsychiatric subjects were compared for reelin ( RE
Autor:
Christine Pesold, Dallas Treit
Publikováno v:
Brain Research. 671:213-221
Microinfusions of the benzodiazepine anxiolytic midazolam into the central or basolateral amygdaloid nuclei produced different anxiolytic effects in two tests of rat 'anxiety'. Infusions into the basolateral nucleus impaired open-arm avoidance in the