Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Christine Péladeau"'
Autor:
Christine Péladeau, Nadine Adam, Lucas M. Bronicki, Adèle Coriati, Mohamed Thabet, Hasanen Al-Rewashdy, Jason Vanstone, Alan Mears, Jean-Marc Renaud, Martin Holcik, Bernard J. Jasmin
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
One potential approach for the treatment of Duchenne muscular dysrophy is to increase expression of the dystrophin homolog utrophin. Here, the authors show that eEF1A2 regulates utrophin expression, and show that 2 FDA-approved drugs upregulate eEIF1
Externí odkaz:
https://doaj.org/article/6bc7a05ce66e4135bb35be45df6c5df1
Autor:
Christine Péladeau, Bernard J. Jasmin
Publikováno v:
Methods in Molecular Biology ISBN: 9781071627716
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc52c0e7efbb21d39daf5eab90da865b
https://doi.org/10.1007/978-1-0716-2772-3_26
https://doi.org/10.1007/978-1-0716-2772-3_26
Autor:
Alan J. Mears, Jean-Marc Renaud, Jason R. Vanstone, Nadine J. Adam, Christine Péladeau, Adele Coriati, Hasanen Al-Rewashdy, Bernard J. Jasmin, Mohamed Thabet, Lucas Bronicki, Martin Holcik
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications
Up-regulation of utrophin in muscles represents a promising therapeutic strategy for the treatment of Duchenne Muscular Dystrophy. We previously demonstrated that eEF1A2 associates with the 5’UTR of utrophin A to promote IRES-dependent translation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2cbd03db8c25171a9ffb2a291c0d77e
https://doaj.org/article/6bc7a05ce66e4135bb35be45df6c5df1
https://doaj.org/article/6bc7a05ce66e4135bb35be45df6c5df1
Autor:
Christine Péladeau, Jagdeep K. Sandhu
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 6068, p 6068 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 6068, p 6068 (2021)
Inflammasomes are molecular hubs that are assembled and activated by a host in response to various microbial and non-microbial stimuli and play a pivotal role in maintaining tissue homeostasis. The NLRP3 is a highly promiscuous inflammasome that is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a297deae4d5ff0e4f318f8898947ec
https://pubmed.ncbi.nlm.nih.gov/34199845
https://pubmed.ncbi.nlm.nih.gov/34199845
Autor:
Bernard J. Jasmin, Christine Péladeau
Publikováno v:
RNA Biol
Internal-ribosomal entry sites (IRES) are translational elements that allow the initiation machinery to start protein synthesis via internal initiation. IRESs promote tissue-specific translation in stress conditions when conventional cap-dependent tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddd977f7690b5b653aac0d496a65ebc0
https://pubmed.ncbi.nlm.nih.gov/33164678
https://pubmed.ncbi.nlm.nih.gov/33164678
Publikováno v:
The FASEB Journal. 32:5090-5103
Duchenne muscular dystrophy (DMD) is a genetic and progressive neuromuscular disorder caused by mutations and deletions in the dystrophin gene. Although there is currently no cure, one promising treatment for DMD is aimed at increasing endogenous lev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b88c2ebfb11427fb7912795c6fd7b52
https://doi.org/10.1096/fj.201800081r
https://doi.org/10.1096/fj.201800081r
Publikováno v:
BMC Cell Biology
Background Formins are a highly conserved family of cytoskeletal remodeling proteins. A growing body of evidence suggests that formins play key roles in the progression and spread of a variety of cancers. There are 15 human formin proteins and of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdba45f0413ca6ae9dd62ee2d0e6deef
https://pubmed.ncbi.nlm.nih.gov/27578625
https://pubmed.ncbi.nlm.nih.gov/27578625
Autor:
Jean-Marc Renaud, Vladimir Ljubicic, Lucas Bronicki, Tara E. Crawford Parks, Adel Amirouche, Aatika Ahmed, Christine Péladeau, Bernard J. Jasmin
Upregulation of utrophin A is an attractive therapeutic strategy for treating Duchenne muscular dystrophy (DMD). Over the years, several studies revealed that utrophin A is regulated by multiple transcriptional and post-transcriptional mechanisms, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6818aba33c6f21535b05787b1f267ed
https://europepmc.org/articles/PMC4690489/
https://europepmc.org/articles/PMC4690489/