Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Christine N. Evans"'
Autor:
Xiuxiu Lu, Venkata R. Sabbasani, Vasty Osei-Amponsa, Christine N. Evans, Julianna C. King, Sergey G. Tarasov, Marzena Dyba, Sudipto Das, King C. Chan, Charles D. Schwieters, Sulbha Choudhari, Caroline Fromont, Yongmei Zhao, Bao Tran, Xiang Chen, Hiroshi Matsuo, Thorkell Andresson, Raj Chari, Rolf E. Swenson, Nadya I. Tarasova, Kylie J. Walters
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Rpn13 is a substrate receptor of the 26S proteasome and an anti-cancer drug target. Here, the authors identify and characterize XL5, a lead compound that binds to the N-terminal Pru domain of human Rpn13 (hRpn13), solve the NMR structure of XL5-ligat
Externí odkaz:
https://doaj.org/article/08204c7dee354ca7ab5e0c3b7e0c28d6
Autor:
Sounak Sahu, Teresa L Sullivan, Alexander Y Mitrophanov, Mélissa Galloux, Darryl Nousome, Eileen Southon, Dylan Caylor, Arun Prakash Mishra, Christine N Evans, Michelle E Clapp, Sandra Burkett, Tyler Malys, Raj Chari, Kajal Biswas, Shyam K Sharan
Publikováno v:
PLoS Genetics, Vol 19, Iss 9, p e1010940 (2023)
The unknown pathogenicity of a significant number of variants found in cancer-related genes is attributed to limited epidemiological data, resulting in their classification as variant of uncertain significance (VUS). To date, Breast Cancer gene-2 (BR
Externí odkaz:
https://doaj.org/article/4f98d76ac09e43ff8da8c27118e6ffce
Autor:
Tim F. Greten, Daniel L. Barber, Clifton E. Barry, Sangmi Oh, Shunsuke Sakai, Raj Chari, Christine N. Evans, Marie Pouzolles, Linda L. Cui, Varun Subramanyam, Bernd Heinrich, Qianfei Zhang, Laurence P. Diggs, Chi Ma, Simon Wabitsch, Vanessa V. Catania, Benjamin Ruf
Mucosal-associated invariant T (MAIT) cells are MR1-restricted innate-like T cells that recognize non-peptide antigens including riboflavin derivates. Although in vitro–activated MAIT cells show antitumor activity, the in vivo role of MAIT cells in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45dd66d0500f2ac40de215037fd687c8
https://doi.org/10.1158/2326-6066.c.6550414.v1
https://doi.org/10.1158/2326-6066.c.6550414.v1
Autor:
Tim F. Greten, Daniel L. Barber, Clifton E. Barry, Sangmi Oh, Shunsuke Sakai, Raj Chari, Christine N. Evans, Marie Pouzolles, Linda L. Cui, Varun Subramanyam, Bernd Heinrich, Qianfei Zhang, Laurence P. Diggs, Chi Ma, Simon Wabitsch, Vanessa V. Catania, Benjamin Ruf
Supplementary Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26617553d2e653a2a460acdf9cd0f464
https://doi.org/10.1158/2326-6066.22543810.v1
https://doi.org/10.1158/2326-6066.22543810.v1
Autor:
Thomas J. Sayers, A.A. Leslie Gunatilaka, Anil Shanker, Thanigaivelan Kanagasabai, Maria T. Prudente de Aquino, Elijah F. Edmondson, Thomas J. Meyer, Curtis J. Henrich, Christine N. Evans, Raj Chari, Timothy C. Back, Ashley L. Babyak, E.M. Kithsiri Wijeratne, Ya-Ming Xu, Alan D. Brooks, Poonam Tewary
Screening for sensitizers of cancer cells to TRAIL-mediated apoptosis identified a natural product of the 17β-hydroxywithanolide (17-BHW) class, physachenolide C (PCC), as a promising hit. In this study, we show that PCC was also able to sensitize m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33932d9c7de3d74ff6195853aab1f552
https://doi.org/10.1158/0008-5472.c.6513079.v1
https://doi.org/10.1158/0008-5472.c.6513079.v1
Autor:
Thomas J. Sayers, A.A. Leslie Gunatilaka, Anil Shanker, Thanigaivelan Kanagasabai, Maria T. Prudente de Aquino, Elijah F. Edmondson, Thomas J. Meyer, Curtis J. Henrich, Christine N. Evans, Raj Chari, Timothy C. Back, Ashley L. Babyak, E.M. Kithsiri Wijeratne, Ya-Ming Xu, Alan D. Brooks, Poonam Tewary
Supplementary Materials & Methods, Supplementary Figures 1-10 with Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6f391c26a6a0bfc9cf3bcd79f37ec05
https://doi.org/10.1158/0008-5472.22428613.v1
https://doi.org/10.1158/0008-5472.22428613.v1
Autor:
R. Kopajtich, Thorkell Andresson, Stephen D. Fox, H. Prokisch, Courtney N. Link, J. Ivanic, Christine N. Evans, Supuni Thalalla Gamage, Jordan L. Meier, S. R. Nance, D. A. Gallimore, Raj Chari
Publikováno v:
Biochemistry 61, 535–544 (2022)
Chemical modification of cytidine in non-coding RNAs plays a key role in regulating translation and disease. However, the distribution and dynamics of many of these modifications remains unknown due to a lack of sensitive site-specific sequencing tec
Autor:
Courtney N. Link, Supuni Thalalla Gamage, Diamond A. Gallimore, Robert Kopajtich, Christine N. Evans, Samantha R. Nance, Stephen D. Fox, Thorkell Andresson, Raj Chari, Joseph Ivanic, Holger Prokisch, Jordan L. Meier
Publikováno v:
The FASEB Journal. 36
Publikováno v:
The FASEB Journal. 36
Autor:
Yong Yean Kim, Robert G. Hawley, Mehal Churiwal, Teresa S. Hawley, Christine N. Evans, Raj Chari, David Milewski, Ranuka Sinniah, Young K. Song, Hsien-Chao Chou, Xinyu Wen, Ying Pang, Jing Wu, Craig J. Thomas, Jun S. Wei, Michele Ceribelli, Javed Khan
Publikováno v:
Cancer Research. 83:3538-3538
Background: Oncogenic fusion genes are attractive therapeutic targets due to their tumor-specific expression and driver roles in cancers. PAX3-FOXO1 (P3F) is the dominant oncogenic driver of fusion-positive rhabdomyosarcoma (FP-RMS) with no targeted