Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Christine N Kay"'
Autor:
Christine N Kay, Renee C Ryals, George V Aslanidi, Seok Hong Min, Qing Ruan, Jingfen Sun, Frank M Dyka, Daniel Kasuga, Andrea E Ayala, Kim Van Vliet, Mavis Agbandje-McKenna, William W Hauswirth, Sanford L Boye, Shannon E Boye
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62097 (2013)
Development of viral vectors capable of transducing photoreceptors by less invasive methods than subretinal injection would provide a major advancement in retinal gene therapy. We sought to develop novel AAV vectors optimized for photoreceptor transd
Externí odkaz:
https://doaj.org/article/acb82117f6a642269cce77147bb4a790
Autor:
Samuel G. Jacobson, Artur V. Cideciyan, Allen C. Ho, Alejandro J. Roman, Vivian Wu, Alexandra V. Garafalo, Alexander Sumaroka, Arun K. Krishnan, Malgorzata Swider, Abraham A. Mascio, Christine N. Kay, Dan Yoon, Kenji P. Fujita, Sanford L. Boye, Igor V. Peshenko, Alexander M. Dizhoor, Shannon E. Boye
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105274- (2022)
Summary: Signaling of vision to the brain starts with the retinal phototransduction cascade which converts visible light from the environment into chemical changes. Vision impairment results when mutations inactivate proteins of the phototransduction
Externí odkaz:
https://doaj.org/article/00767dff06174533bc77d98fb800d731
Autor:
Eleonora M. Lad, Jacque L. Duncan, Wendi Liang, Maureen G. Maguire, Allison R. Ayala, Isabelle Audo, David G. Birch, Joseph Carroll, Janet K. Cheetham, Todd A. Durham, Abigail T. Fahim, Jessica Loo, Zengtian Deng, Dibyendu Mukherjee, Elise Heon, Robert B. Hufnagel, Bin Guan, Alessandro Iannaccone, Glenn J. Jaffe, Christine N. Kay, Michel Michaelides, Mark E. Pennesi, Ajoy Vincent, Christina Y. Weng, Sina Farsiu
Publikováno v:
American Journal of Ophthalmology. 244:98-116
To investigate baseline mesopic microperimetry (MP) and spectral domain optical coherence tomography (OCT) in the Rate of Progression in USH2A-related Retinal Degeneration (RUSH2A) study.Natural history study METHODS: Setting: 16 clinical sites in Eu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f14a61ec669464d54f804a6d4239c19d
https://doi.org/10.1016/j.ajo.2022.08.013
https://doi.org/10.1016/j.ajo.2022.08.013
Publikováno v:
Cureus.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98ad2f5fde56c7920715534c76208451
https://doi.org/10.7759/cureus.27502
https://doi.org/10.7759/cureus.27502
Autor:
Christine N. Kay
Publikováno v:
International Ophthalmology Clinics. 61:149-155
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5575f4b350e8177e55e0fec9629c29f1
https://doi.org/10.1097/iio.0000000000000379
https://doi.org/10.1097/iio.0000000000000379
Autor:
Jacques P. Tremblay, Jerry R. Mendell, Barry J. Byrne, Shannon E. Boye, Louise R. Rodino-Klapac, Christine N. Kay, Kimberly Goodspeed, Samiah Al-Zaidy, Sanford L. Boye, Steven J. Gray, Lindsey A. George, Stephanie Salabarria, Manuela Corti
Publikováno v:
Molecular Therapy
Hereditary diseases are caused by mutations in genes, and more than 7,000 rare diseases affect over 30 million Americans. For more than 30 years, hundreds of researchers have maintained that genetic modifications would provide effective treatments fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3831b0f3997b7651501a426533e48fed
http://europepmc.org/articles/PMC7854298
http://europepmc.org/articles/PMC7854298
Publikováno v:
Ophthalmic Surgery, Lasers and Imaging Retina. 52:350-352
This case report describes an unusual presentation of arteritic anterior ischemic optic neuropathy (AAION) in a 68-year-old patient with retinitis pigmentosa (RP) secondary to Usher syndrome. The authors report a patient with RP who presented with ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02aaa26f005aef1144e7a65b92e75609
https://doi.org/10.3928/23258160-20210528-08
https://doi.org/10.3928/23258160-20210528-08
Autor:
Christine N. Kay, Byron L. Lam, Ninel Z. Gregori, Janet L. Davis, Harrison Dermer, Rehan M. Hussain
Publikováno v:
International Ophthalmology Clinics. 59:83-110
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f5dba1030287367ca8bb5f533305c9
https://doi.org/10.1097/iio.0000000000000259
https://doi.org/10.1097/iio.0000000000000259
Autor:
Christine N. Kay, Alicia Chacon, Thomas B. Connor, William W. Hauswirth, Erica N. Woertz, Michel Michaelides, Mark E. Pennesi, Kimberly E Stepien, Joseph Carroll, Byron L. Lam, Niamh Wynne, Sasha Strul, C. Gail Summers, Arlene V. Drack, Brian P. Brooks, Deborah M. Costakos, Katie M. Litts, Alina V. Dumitrescu, Gerald A. Fishman
Publikováno v:
Translational Vision Science & Technology
Purpose Adaptive optics scanning light ophthalmoscopy (AOSLO) imaging in patients with achromatopsia (ACHM) and albinism is not always successful. Here, we tested whether optical coherence tomography (OCT) measures of foveal structure differed betwee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e05e509e67856dcc389146a677f05773
http://europepmc.org/articles/PMC8132001
http://europepmc.org/articles/PMC8132001
Autor:
William W. Hauswirth, Erica N. Woertz, Christine N. Kay, Katie M. Litts, Mark E. Pennesi, Michel Michaelides, Michalis Georgiou, Gerald A. Fishman, Byron L. Lam, Joseph Carroll, Emily J Patterson
Publikováno v:
Translational Vision Science & Technology
Purpose: To determine whether artifacts in optical coherence tomography (OCT) images are associated with the success or failure of adaptive optics scanning light ophthalmoscopy (AOSLO) imaging in subjects with achromatopsia (ACHM). / Methods: Previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8a79e58ba086c8e74627c2fe580ad26
http://europepmc.org/articles/PMC7804582
http://europepmc.org/articles/PMC7804582