Zobrazeno 1 - 10 of 49 pro vyhledávání: '"Christine N, Sang"'
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Akademický článek
Gene therapy for diabetic peripheral neuropathy: A randomized, placebo‐controlled phase III study of VM202, a plasmid DNA encoding human hepatocyte growth factor
Autor: John A. Kessler, Aziz Shaibani, Christine N. Sang, Mark Christiansen, David Kudrow, Aaron Vinik, Nari Shin, the VM202 study group
Publikováno v: Clinical and Translational Science, Vol 14, Iss 3, Pp 1176-1184 (2021)
Abstract VM202 is a plasmid DNA encoding two isoforms of hepatocyte growth factor (HGF). A previous phase II study in subjects with painful diabetic peripheral neuropathy (DPN) showed significant reductions in pain. A phase III study was conducted to
Externí odkaz: https://doaj.org/article/2329437b42c343839e9410cee955d372
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5
The DiSCover Project: Protocol and Baseline Characteristics of a Decentralized Digital Study Assessing Chronic Pain Outcomes and Behavioral Data
Autor: Jessie L. Juusola, Christian J. Cerrada, Caroline G. Tai, Mai Ka Ying Vang, Christine N. Sang, Jennifer L.A. Tran, Jennifer L. Lee, Kelly Scherer
BackgroundChronic pain affects approximately 50 million adults in the United States and impacts mood, everyday functioning, and quality of life. The challenges of analgesic clinical trials and, therefore, the approval of new non-opioid analgesics, ar
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7608fb20a19af5f3461f93bd49709ee0
https://doi.org/10.1101/2021.07.14.21260523
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6
A Chronology for the Identification and Disclosure of Adverse Effects of Succinylcholine
Autor: Manisha Desai, Christine N. Sang, Lisa Huang
Publikováno v: Journal of Anesthesia History. 5:65-84
Background New therapies are created to address specific problems and enjoy popularity as they enter widespread clinical use. Broader use can reveal unknown adverse effects and impact the life cycle significantly. Succinylcholine, a depolarizing neur
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0275b2f18a73d39d6f170de22dce80
https://doi.org/10.1016/j.janh.2018.07.003
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7
Elektronická kniha
Spinal Cord Injury Pain
Autor: Christine N. Sang, Claire E. Hulsebosch
Spinal Cord Injury Pain presents the basis for preclinical and clinical investigations, along with strategies for new approaches in the treatment of central neuropathic pain. Contributors from the private sector and academia provide a comprehensive r
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8
Phase IA Clinical Trial Evaluating the Tolerability, Pharmacokinetics, and Analgesic Efficacy of an Intrathecally Administered Neurotensin A Analogue in Central Neuropathic Pain Following Spinal Cord Injury
Autor: Christine N. Sang, Steven E. Kern, Kate J. Barnabe
Publikováno v: Clinical Pharmacology in Drug Development. 5:250-258
We evaluated CGX-1160 in a Phase Ia clinical trial to determine the safety of escalating doses in patients with central neuropathic pain following spinal cord injury (SCI). Our secondary objective was to detect a trend toward analgesic efficacy. Four
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f82e15f65d41846de8edc159f5e4a6f0
https://doi.org/10.1002/cpdd.253
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10
Indications for Opioid Antagonists
Autor: O. J. Michael Coppes, Christine N. Sang
Publikováno v: Current pain and headache reports. 21(6)
As opioids have become more common in clinical practice for the treatment of both acute and chronic pain, so too has the need for a deeper understanding of the clinical applications of opioid antagonists. The purpose of this review is to present both
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c30fafa3e76985c5c9e6e0a1007ed345
https://pubmed.ncbi.nlm.nih.gov/28547246
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