Characterisation of Early Positive mcr-1 Resistance Gene and Plasmidome in Escherichia coli Pathogenic Strains Associated with Variable Phylogroups under Colistin Selection

Autor: Guerrino Macori, Scott V. Nguyen, Ankita Naithani, Daniel Hurley, Li Bai, Farid El Garch, Frédérique Woehrlé, Christine Miossec, Benjamin Roques, Peadar O’Gaora, James L. Bono, Séamus Fanning

Publikováno v: Antibiotics, Vol 10, Iss 9, p 1041 (2021)

An antibiotic susceptibility monitoring programme was conducted from 2004 to 2010, resulting in a collection of 143 Escherichia coli cultured from bovine faecal samples (diarrhoea) and milk-aliquots (mastitis). The isolates were subjected to whole-ge

Externí odkaz: https://doaj.org/article/3d8c42f76ba84476a065dd6e51a9eede

Characterisation of Early Positive mcr-1 Resistance Gene and Plasmidome in Escherichia coli Pathogenic Strains Associated with Variable Phylogroups under Colistin Selection

Autor: James L. Bono, Frédérique Woehrlé, Farid El Garch, Scott V. Nguyen, Benjamin Roques, Daniel Hurley, Li Bai, Guerrino Macori, Séamus Fanning, Ankita Naithani, Peadar O'Gaora, Christine Miossec

Publikováno v: Antibiotics
Antibiotics, Vol 10, Iss 1041, p 1041 (2021)
Volume 10
Issue 9
Macori, G, Nguyen, S V, Naithani, A, Hurley, D, Bai, L, El Garch, F, Woehrlé, F, Miossec, C, Roques, B, O’Gaora, P, Bono, J L & Fanning, S 2021, ' Characterisation of Early Positive mcr-1 Resistance Gene and Plasmidome in Escherichia coli Pathogenic Strains Associated with Variable Phylogroups under Colistin Selection ', Antibiotics, vol. 10, no. 9, 1041 . https://doi.org/10.3390/antibiotics10091041

An antibiotic susceptibility monitoring programme was conducted from 2004 to 2010, resulting in a collection of 143 Escherichia coli cultured from bovine faecal samples (diarrhoea) and milk-aliquots (mastitis). The isolates were subjected to whole-ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0529404a3e45638faed93a324caa579f
http://europepmc.org/articles/PMC8466100

Investigation of the effect of the adsorbent DAV131A on the propensity of moxifloxacin to induce simulated Clostridioides (Clostridium) difficile infection (CDI) in an in vitro human gut model

Autor: Antoine Andremont, G S Crowther, C H Chilton, Mark H. Wilcox, J de Gunzburg, Christine Miossec

Publikováno v: The Journal of antimicrobial chemotherapy. 75(6)

Background Clostridioides difficile infection (CDI) remains a high burden worldwide. DAV131A, a novel adsorbent, reduces residual gut antimicrobial levels, reducing CDI risk in animal models. Objectives We used a validated human gut model to investig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a73924e8ee6e742b024da61d25475d80
https://pubmed.ncbi.nlm.nih.gov/32097465

In Vitro Antibacterial Activity of the Ceftazidime-Avibactam Combination against Enterobacteriaceae, Including Strains with Well-Characterized β-Lactamases

Autor: Christine Miossec, Ken Coleman, Anne-Marie Girard, John L. Pace, Premavathy Levasseur

Publikováno v: Antimicrobial Agents and Chemotherapy. 59:1931-1934

The novel β-lactamase inhibitor avibactam is a potent inhibitor of class A, class C, and some class D enzymes. The in vitro antibacterial activity of the ceftazidime-avibactam combination was determined for a collection of Enterobacteriaceae clinica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90095900bf1fe876711d0682817838ac
https://doi.org/10.1128/aac.04218-14

Efficacy of a Ceftazidime-Avibactam Combination in a Murine Model of Septicemia Caused by Enterobacteriaceae Species Producing AmpC or Extended-Spectrum β-Lactamases

Autor: Kenneth Coleman, Premavathy Levasseur, Ludovic Lavallade, Christine Miossec, Anne-Marie Girard, John L. Pace

Publikováno v: Antimicrobial Agents and Chemotherapy. 58:6490-6495

Avibactam is a novel non-β-lactam β-lactamase inhibitor that has been shown in vitro to inhibit class A, class C, and some class D β-lactamases. It is currently in phase 3 of clinical development in combination with ceftazidime. In this study, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a6e36d634ec307a8e3af925593a7662
https://doi.org/10.1128/aac.03579-14