Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Christine Mehner"'
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102264- (2023)
Summary: Multicellular spheroids are useful models for drug testing or studying tumor biology, but their production requires specialized approaches. Here, we present a protocol to produce viable spheroids by slow rotation around a horizontal axis usi
Externí odkaz:
https://doaj.org/article/ef8e959d26fc4b3ba1a80b5921309d7d
Autor:
Giulia Silvani, Peta Bradbury, Carin Basirun, Christine Mehner, Detina Zalli, Kate Poole, Joshua Chou
Publikováno v:
npj Microgravity, Vol 8, Iss 1, Pp 1-11 (2022)
Abstract The advancement of microgravity simulators is helping many researchers better understanding the impact of the mechanically unloaded space environment on cellular function and disfunction. However, performing microgravity experiments on Earth
Externí odkaz:
https://doaj.org/article/77f2687b679e4324a1d3ce002e6e8e71
Autor:
Hakim Ullah Wazir, Pooja Narang, Giulia Silvani, Christine Mehner, Kate Poole, Catherine Burke, Joshua Chou
Publikováno v:
Life, Vol 13, Iss 3, p 656 (2023)
With the advancement in reusable rocket propulsion technology, space tourist trips into outer space are now becoming a possibility at a cost-effective rate. As such, astronauts will face a host of health-related challenges, particularly on long-durat
Externí odkaz:
https://doaj.org/article/62f12751584c4468a9177d782fdabb93
Autor:
Christine Mehner, Evette S. Radisky
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Externí odkaz:
https://doaj.org/article/fc34afdd39d4486fb638c84a45b447e6
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75836 (2013)
Matrix metalloproteinases (MMPs) play central roles in vertebrate tissue development, remodeling, and repair. The endogenous tissue inhibitors of metalloproteinases (TIMPs) regulate proteolytic activity by binding tightly to the MMP active site. Whil
Externí odkaz:
https://doaj.org/article/453e2228cb7d4d5dab6f9c81eaa13123
Autor:
Jyotica Batra, Jessica Robinson, Christine Mehner, Alexandra Hockla, Erin Miller, Derek C Radisky, Evette S Radisky
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50028 (2012)
Excess proteolytic activity of matrix metalloproteinases (MMPs) contributes to the development of arthritis, cardiovascular diseases and cancer progression, implicating these enzymes as therapeutic targets. While many small molecule inhibitors of MMP
Externí odkaz:
https://doaj.org/article/3c3cbb103e984d14a89493ad8be73394
Autor:
Derek C. Radisky, Howard C. Crawford, Evette S. Radisky, Jens Waldmann, Lizhi Zhang, William R. Bamlet, Ann L. Oberg, Aziza Nassar, Davitte Khauv, Erin Miller, Christine Mehner
PDF file - 50K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddea776ae3172bbc3490fbedf80f4d64
https://doi.org/10.1158/1541-7786.22514128
https://doi.org/10.1158/1541-7786.22514128
Autor:
Derek C. Radisky, Howard C. Crawford, Evette S. Radisky, Jens Waldmann, Lizhi Zhang, William R. Bamlet, Ann L. Oberg, Aziza Nassar, Davitte Khauv, Erin Miller, Christine Mehner
XLSX file - 14K, Supplemental Table 4. Gene Ontology categories enriched in transcriptional profiles of cells treated with MMP-3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87f8a21b05c5621acd4f11cda1239e1b
https://doi.org/10.1158/1541-7786.22514113.v1
https://doi.org/10.1158/1541-7786.22514113.v1
Autor:
Derek C. Radisky, Howard C. Crawford, Evette S. Radisky, Jens Waldmann, Lizhi Zhang, William R. Bamlet, Ann L. Oberg, Aziza Nassar, Davitte Khauv, Erin Miller, Christine Mehner
PDF file - 883K, Supplemental Figure 1. MMP3 and Rac1b expression are not correlated with collagen and smooth muscle actin in pancreatic adenocarcinoma cells. Supplemental Figure 2. Association of Rac1b subcellular localization with patient prognosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3953eb8b833116a2cbe100d7eda6f589
https://doi.org/10.1158/1541-7786.22514125.v1
https://doi.org/10.1158/1541-7786.22514125.v1
Autor:
Derek C. Radisky, Howard C. Crawford, Evette S. Radisky, Jens Waldmann, Lizhi Zhang, William R. Bamlet, Ann L. Oberg, Aziza Nassar, Davitte Khauv, Erin Miller, Christine Mehner
XLSX file - 59K, Supplemental Table 3. Gene expression changes in response to MMP-3 treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57641a78cd976df62ac7b830a529883d
https://doi.org/10.1158/1541-7786.22514116.v1
https://doi.org/10.1158/1541-7786.22514116.v1