FOXR1 regulates stress response pathways and is necessary for proper brain development

Autor: Andressa Mota, Hannah K. Waxman, Rui Hong, Gavin D. Lagani, Sheng-Yong Niu, Féodora L. Bertherat, Lynne Wolfe, Christine May Malicdan, Thomas C. Markello, David R. Adams, William A. Gahl, Christine S. Cheng, Uwe Beffert, Angela Ho

Publikováno v: PLoS Genetics, Vol 17, Iss 11 (2021)

The forkhead box (Fox) family of transcription factors are highly conserved and play essential roles in a wide range of cellular and developmental processes. We report an individual with severe neurological symptoms including postnatal microcephaly,

Externí odkaz: https://doaj.org/article/c1ff14fa39f34f54ada5c832ebbe40c8

FOXR1 regulates stress response pathways and is necessary for proper brain development.

Autor: Mota, Andressa¹ (AUTHOR), Waxman, Hannah K.¹ (AUTHOR), Hong, Rui^1,2 (AUTHOR), Lagani, Gavin D.¹ (AUTHOR), Niu, Sheng-Yong¹ (AUTHOR), Bertherat, Féodora L.¹ (AUTHOR), Wolfe, Lynne³ (AUTHOR), Malicdan, Christine May³ (AUTHOR), Markello, Thomas C.³ (AUTHOR), Adams, David R.³ (AUTHOR), Gahl, William A.³ (AUTHOR), Cheng, Christine S.^1,2 (AUTHOR), Beffert, Uwe¹ (AUTHOR) ub1@bu.edu, Ho, Angela¹ (AUTHOR) ub1@bu.edu

Publikováno v: PLoS Genetics. 11/1/2021, Vol. 17 Issue 11, p1-30. 30p.