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of 3
pro vyhledávání: '"Christine Maierhofer"'
Autor:
Michael R. Speicher, Christine Maierhofer, Bert Vogelstein, Christoph Lengauer, Tian Li Wang, Kenneth W. Kinzler, Victor E. Velculescu
Publikováno v:
Proceedings of the National Academy of Sciences. 99:16156-16161
Alterations in the genetic content of a cell are the underlying cause of many human diseases, including cancers. We have developed a method, called digital karyotyping, that provides quantitative analysis of DNA copy number at high resolution. This a
Publikováno v:
Mutagen. 17, 523-527 (2002)
Chemicals may induce both numerical and structural aberrations. In addition to these chromosomal mutations, chemicals may render cells genetically unstable, which may result in chromosomal instability. For a detailed analysis, sophisticated approache
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b1918b0892b9c819d13ed929248a547
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=23566
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=23566
Autor:
Simone Schuffenhauer, Sabine Langer, Jay Reichman, Andreas Bolzer, Jorge Azofeifa, Christine Fauth, Michael R. Speicher, Christine Maierhofer, Jürgen Kraus
Publikováno v:
The American Journal of Human Genetics. (5):1684-1688
The rapid spread of the use of new 24-color karyotyping techniques has preceded their standardization. This is best documented by the fact that the exact resolution limits have not yet been defined. Indeed, it is shown here that a substantial proport