Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Christine M. Rostosky"'
Autor:
John D. Murdoch, Christine M. Rostosky, Sindhuja Gowrisankaran, Amandeep S. Arora, Sandra-Fausia Soukup, Ramon Vidal, Vincenzo Capece, Siona Freytag, Andre Fischer, Patrik Verstreken, Stefan Bonn, Nuno Raimundo, Ira Milosevic
Publikováno v:
Cell Reports, Vol 17, Iss 4, Pp 1071-1086 (2016)
Endophilin-A, a well-characterized endocytic adaptor essential for synaptic vesicle recycling, has recently been linked to neurodegeneration. We report here that endophilin-A deficiency results in impaired movement, age-dependent ataxia, and neurodeg
Externí odkaz:
https://doaj.org/article/b3675368bb464b4481786ffb5883f006
Autor:
Sylvia Torres-Odio, Ira Milosevic, Ola Senderovich, Esther G. Meyron-Holtz, Christine M Rostosky, Angela Sanchez-Guerrero, Jens Frahm, Takashi Watanabe, Nuno Raimundo, King Faisal Yambire, A. Phillip West, David Pacheu-Grau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db36743b82cb9ce626ccd5a41c245ba4
https://doi.org/10.7554/elife.51031.sa2
https://doi.org/10.7554/elife.51031.sa2
Autor:
Takashi Watanabe, Ira Milosevic, David Pacheu-Grau, King Faisal Yambire, Nuno Raimundo, Ola Senderovich, Jens Frahm, Angela Sanchez-Guerrero, Christine M Rostosky, Esther G. Meyron-Holtz, A. P. West, Sylvia Torres-Odio
SUMMARYLysosomal acidification is a key feature of healthy cells. Inability to maintain lysosomal acidic pH is associated with aging and neurodegenerative diseases. However, the mechanisms elicited by impaired lysosomal acidification remain unknown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20e986beda0251efc26c1674ac87e34c
Autor:
King Faisal Yambire, Christine M Rostosky, Esther G. Meyron-Holtz, Angela Sanchez-Guerrero, A. Phillip West, David Pacheu-Grau, Nuno Raimundo, Ola Senderovich, Jens Frahm, Ira Milosevic, Sylvia Torres-Odio, Takashi Watanabe
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
Lysosomal acidification is a key feature of healthy cells. Inability to maintain lysosomal acidic pH is associated with aging and neurodegenerative diseases. However, the mechanisms elicited by impaired lysosomal acidification remain poorly understoo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d708619492af0a13dada6f5fe603a894
http://resolver.sub.uni-goettingen.de/purl?gs-1/17114
http://resolver.sub.uni-goettingen.de/purl?gs-1/17114
Autor:
Christine M Rostosky, Ira Milosevic
Publikováno v:
J Vis Exp
Motor behavior tests are commonly used to determine the functional relevance of a rodent model and to test newly developed treatments in these animals. Specifically, gait analysis allows recapturing disease relevant phenotypes that are observed in hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9633b139fa5e4e668ca9afc2ac7ac43f
https://doi.org/10.3791/57752-v
https://doi.org/10.3791/57752-v
Autor:
Jonathan G. Hanley, Marcio Baptista, Alexei M. Bygrave, Christine M Rostosky, Ira Milosevic, Gabrielle T. Parkinson, Maria Fiuza, Nagaraj D. Halemani
Publikováno v:
The Journal of Cell Biology
Fiuza, M, Rostosky, C, Parkinson, G, Bygrave, A, Halemani, N, Baptista, M, Milosevic, I & Hanley, J 2017, ' PICK1 regulates AMPA receptor endocytosis via direct interactions with AP2 α-appendage and dynamin ', Journal of Cell Biology, vol. 216, no. 10, pp. 3323-3338 . https://doi.org/10.1083/jcb.201701034
Fiuza, M, Rostosky, C, Parkinson, G, Bygrave, A, Halemani, N, Baptista, M, Milosevic, I & Hanley, J 2017, ' PICK1 regulates AMPA receptor endocytosis via direct interactions with AP2 α-appendage and dynamin ', Journal of Cell Biology, vol. 216, no. 10, pp. 3323-3338 . https://doi.org/10.1083/jcb.201701034
Fiuza et al. report that PICK1 localizes to clathrin-coated pits and makes direct, functional interactions with the endocytic adapter complex AP2 and dynamin. The PICK1–AP2 interaction is required for clustering AMPA receptors at endocytic sites an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09d1239f05ed273c1b2d064eedcbf7a9
https://pubmed.ncbi.nlm.nih.gov/28855251
https://pubmed.ncbi.nlm.nih.gov/28855251