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pro vyhledávání: '"Christine M. Pedroarena"'
Autor:
Christine M. Pedroarena
Publikováno v:
J Neurosci
Modifications in the sensitivity of neural elements allow the brain to adapt its functions to varying demands. Frequency-dependent short-term synaptic depression (STD) provides a dynamic gain-control mechanism enabling adaptation to different backgro
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Autor:
Christine M. Pedroarena
Modifications in the sensitivity of neural elements allow the brain to adapt its functions to varying demands. Frequency-dependent short-term synaptic depression (STD) provides a dynamic gain-control mechanism enabling adaptation to different backgro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d30f41cc1f626448ba23543570c9fd9
https://doi.org/10.1101/749259
https://doi.org/10.1101/749259
Autor:
Christine M. Pedroarena
Publikováno v:
The Cerebellum. 10:647-658
Deep cerebellar nuclear neurons (DCNs) display characteristic electrical properties, including spontaneous spiking and the ability to discharge narrow spikes at high frequency. These properties are thought to be relevant to processing inhibitory Purk
Publikováno v:
Neuropharmacology. 54:784-795
Despite evidence of local glycinergic circuits in the mature cerebellar nuclei the result of their activation remains unknown. Here, using whole cell recordings in rat cerebellar slices we demonstrated that after postnatal day 17 (>P17) glycinergic I
Publikováno v:
Journal of Neurophysiology. 91:1102-1107
In heterozygous Lurcher mice ( Lc/+), the Purkinje cells (PCs) degenerate almost totally during postnatal development. On the other hand, their projection target, the deep cerebellar nuclei (DCN), shows few signs of degeneration and seems to play an
Publikováno v:
Journal of Neurophysiology. 89:704-715
Although the entire output of the cerebellar cortex is conveyed to the deep cerebellar nuclei neurons (DCNs) via the GABAergic synapses established by Purkinje cells (PCs), very little is known about the strength and dynamic properties of PC-DCN conn
Publikováno v:
Proceedings of the National Academy of Sciences. 94:724-728
Cortical-projecting thalamic neurons, in guinea pig brain slices, display high-frequency membrane potential oscillations (20–80 Hz), when their somata are depolarized beyond −45 mV. These oscillations, preferentially located at dendritic sites, a
Autor:
Marco Benevento, Stefanie Alber, Christine M. Pedroarena, Simone Di Giovanni, Carolin Jacob, Giorgia Quadrato, Mohamed Y. Elnaggar, Tuan Nguyen, Elisa M. Floriddia, Jeffrey D. Molkentin
Publikováno v:
Proceedings of the National Academy of Sciences USA, 109, 23, pp. E1499-508
Proceedings of the National Academy of Sciences USA, 109, E1499-508
Proceedings of the National Academy of Sciences USA, 109, E1499-508
New neurons generated in the adult dentate gyrus are constantly integrated into the hippocampal circuitry and activated during encoding and recall of new memories. Despite identification of extracellular signals that regulate survival and integration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48a2ccab69316b89f6f2a7e4a9d924d5
https://doi.org/10.1073/pnas.1202068109
https://doi.org/10.1073/pnas.1202068109
Publikováno v:
Journal of neurophysiology. 106(5)
Following hyperpolarizing inputs, many neurons respond with an increase in firing rate, a phenomenon known as rebound excitation. Rebound excitation has been proposed as a mechanism to encode and process inhibitory signals and transfer them to target