Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Christine M. Dengler-Crish"'
Autor:
Weixin Li, Kun-Woo Rafael Kim, Donglan Zhang, Bian Liu, Christine M. Dengler-Crish, Ming Wen, Lu Shi, Xi Pan, Yian Gu, Yan Li
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-15 (2023)
Abstract Background Although increasing physical activity (PA) has been suggested to prevent and manage cognitive decline and dementia, its economic impact on healthcare systems and society is largely unknown. This study aimed to summarize evidence o
Externí odkaz:
https://doaj.org/article/e00e8eb9403f432a913e2c6898c8af4d
Autor:
Xi Pan, Donglan Zhang, Ji Haeng Heo, Chanhyun Park, Gang Li, Christine M. Dengler-Crish, Yan Li, Yian Gu, Henry N. Young, Devin L. Lavender, Lu Shi
Publikováno v:
Drugs & Aging. 39:875-886
Epidemiological evidence on different classes of antihypertensives and risks of Alzheimer's disease and related dementias (ADRD) is inconclusive and limited. This study examined the association between antihypertensive use (including therapy type and
Autor:
Sheila M. Fleming, Matthew A. Smith, Li Lin, Kimberly M. Bretland, Christine M. Dengler-Crish, Katie A Bretland
Publikováno v:
Neuropathology and Applied Neurobiology. 47:967-978
Aims Irisin is a hormone cleaved from fibronectin type-III domain-containing protein 5 in response to exercise and may be therapeutic in Alzheimer's disease (AD). Irisin is shown to repair damage caused by midlife cardiometabolic risk factors for AD
Autor:
Gabrielle Frame, Adam Schuller, Matthew A. Smith, Samuel D. Crish, Christine M. Dengler-Crish
Publikováno v:
Journal of Alzheimer's disease : JAD. 88(2)
Background: Visual disturbances often precede cognitive dysfunction in patients with Alzheimer’s disease (AD) and may coincide with early accumulation of amyloid-β (Aβ) protein in the retina. These findings have inspired critical research on in v
Autor:
Gina Nicole Wilson, Matthew Alan Smith, Denise M Inman, Christine M Dengler-Crish, Samuel David Crish
Publikováno v:
Frontiers in Neuroscience, Vol 10 (2016)
Axonal transport deficits precede structural loss in glaucoma and other neurodegenerations. Impairments in structural support, including modified cytoskeletal proteins and microtubule-destabilizing elements, could be initiating factors in glaucoma pa
Externí odkaz:
https://doaj.org/article/26633b7000174e1a943adb5efb33a2c3
Autor:
Nobuyuki Kutsukake, Jonathan B. Levitt, Kazuo Okanoya, Cynthia Kenyon, Jane Reznick, Andrei Seluanov, Sonja J. Pyott, Clive W. Coen, Nigel C. Bennett, Timothy P. O'Connor, Amanda M. Lauer, Samantha Lagestee, Alyssa Shepard, Daniel P. McCloskey, Diana K. Sarko, J. Graham Ruby, Melissa M. Holmes, Joseph Santos-Sacchi, Walid T. Khaled, Angela Lee, Kazutaka Mogi, Emily N. Vice, Vera Gorbunova, Chris G. Faulkes, Gary N. Bronner, Thomas J. Park, Stanislav Avdieiev, Martha A. Delaney, Xiao Tian, Matthew J. Mason, Kenneth B. Storey, Mary McMahon, Vincent Amoroso, Blazej Andziak, Jorge Azpurua, M. Justin O'Riain, Vikram Narayan, Michael Zions, Kaitlyn N. Lewis Hardell, Mélanie Viltard, Elena D. Zemlemerova, Megan Smith, Ewa Wywial, TzuHua D. Lin, Akiyuki Watarai, Joseph L. Kissil, Ewan St. John Smith, Patrick A. Gibney, Yael H. Edrey, Ned J. Place, Christopher Hine, Yoshimi Kawamura, Gérard Friedlander, Rochelle Buffenstein, Miguel A. Brieño-Enríquez, Katie Podshivalova, Gary R. Lewin, Matthew E. Pamenter, John Larson, Jennifer U. M. Jarvis, Masanori Yamakawa, Christine M. Dengler-Crish, Takefumi Kikusui, Leonid A. Lavrenchenko, Kyoko Miura, Adam B. Salmon, Daniel Frankel, Alison J. Barker
Publikováno v:
Biological Reviews, 115-140. Wiley
ISSUE=97;STARTPAGE=115;ENDPAGE=140;ISSN=1464-7931;TITLE=Biological Reviews
Biol Rev Camb Philos Soc.
ISSUE=97;STARTPAGE=115;ENDPAGE=140;ISSN=1464-7931;TITLE=Biological Reviews
Biol Rev Camb Philos Soc.
Funder: Calico Life Sciences, LLC
The naked mole‐rat (Heterocephalus glaber) has fascinated zoologists for at least half a century. It has also generated considerable biomedical interest not only because of its extraordinary longevity, but als
The naked mole‐rat (Heterocephalus glaber) has fascinated zoologists for at least half a century. It has also generated considerable biomedical interest not only because of its extraordinary longevity, but als
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0376a65ef2d13347b39acb9988322bbe
https://www.repository.cam.ac.uk/handle/1810/327561
https://www.repository.cam.ac.uk/handle/1810/327561
Autor:
Christine M Dengler-Crish, Matthew A Smith, Denise M Inman, Jesse W Young, Gina N Wilson, Samuel D Crish
Publikováno v:
Frontiers in Neuroscience, Vol 8 (2014)
Axonal transport deficits have been reported as an early pathology in several neurodegenerative disorders, including glaucoma. However, the progression and mechanisms of these deficits are poorly understood. Previous work suggests that anterograde tr
Externí odkaz:
https://doaj.org/article/8eb9d8ed2fe843678b988286ee135b67
Autor:
null Katie A. Bretland, null Li Lin, null Kimberly M. Bretland, null Matthew A. Smith, null Sheila M. Fleming, null Christine M. Dengler‐Crish
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2aea8da83af635828e4e61c6746acda3
https://doi.org/10.1111/nan.12711/v3/response1
https://doi.org/10.1111/nan.12711/v3/response1
Publikováno v:
Connective Tissue Research. 61:4-18
Purpose/Aim: Alzheimer's disease (AD), the primary cause of dementia in the elderly, is one of the leading age-related neurodegenerative diseases worldwide. While AD is notorious for destroying memory and cognition, dementia patients also experience
Publikováno v:
Neuroscience. 390:104-118
Retinal ganglion cell axons of the DBA/2J mouse model of glaucoma, a model characterized by extensive neuroinflammation, preserve synaptic contacts with their subcortical targets for a time after onset of anterograde axonal transport deficits, axon t