Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Christine M. Barbon"'
Publikováno v:
Cell Transplantation, Vol 21 (2012)
Ex vivo alloanergization of human immune cells, via allostimulation in the presence of costimulatory blockade with either a combination of anti-B7.1 and anti-B7.2 antibodies or first-generation cytotoxic T-lymphocyte antigen 4-immunoglobulin (CTLA4-I
Externí odkaz:
https://doaj.org/article/9917ab872c68469eb03db47457f8b329
Autor:
Alexandra, Borodovsky, Christine M, Barbon, Yanjun, Wang, Minwei, Ye, Laura, Prickett, Dinesh, Chandra, Joseph, Shaw, Nanhua, Deng, Kris, Sachsenmeier, James D, Clarke, Bolan, Linghu, Giles A, Brown, James, Brown, Miles, Congreve, Robert Ky, Cheng, Andrew S, Dore, Edward, Hurrell, Wenlin, Shao, Richard, Woessner, Corinne, Reimer, Lisa, Drew, Stephen, Fawell, Alwin G, Schuller, Deanna A, Mele
Publikováno v:
Journal for Immunotherapy of Cancer
Accumulation of extracellular adenosine within the microenvironment is a strategy exploited by tumors to escape detection by the immune system. Adenosine signaling through the adenosine 2A receptor (A2AR) on immune cells elicits a range of immunosupp
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1899
Alloantigen-specific hyporesponsiveness can be induced in alloreactive T cells contained within the whole peripheral blood mononuclear cell (PBMC) population by stimulating these responder cells ex vivo with HLA-mismatched stimulator PBMC as the anti
Publikováno v:
Methods in Molecular Biology ISBN: 9781493989362
Alloantigen-specific hyporesponsiveness can be induced in alloreactive T cells contained within the whole peripheral blood mononuclear cell (PBMC) population by stimulating these responder cells ex vivo with HLA-mismatched stimulator PBMC as the anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c98ba2143c75c1c7a90c264db19bad9
https://doi.org/10.1007/978-1-4939-8938-6_8
https://doi.org/10.1007/978-1-4939-8938-6_8
Autor:
Edward Hurrell, James A. Brown, Andrew S. Doré, Christine M. Barbon, Stephen Fawell, Robert K. Y. Cheng, Bolan Linghu, Giles A. Brown, Joseph Shaw, Kris Sachsenmeier, Alexandra Borodovsky, Minwei Ye, Alwin Schuller, Wenlin Shao, Dinesh Chandra, James D. Clarke, Yanjun Wang, Laura Prickett, Miles Congreve, Lisa Drew, Corinne Reimer, Deanna A. Mele, Richard Woessner, Nanhua Deng
Publikováno v:
Journal for ImmunoTherapy of Cancer. 8:e000417
Accumulation of extracellular adenosine within the microenvironment is a strategy exploited by tumors to escape detection by the immune system. Adenosine signaling through the adenosine 2A receptor (A2AR) on immune cells elicits a range of immunosupp
Autor:
Dinesh Chandra, Minwei Ye, Christine M. Barbon, Kris Sachsenmeier, Deanna A. Mele, Wenlin Shao, Carl Barrett, Stephen Fawell, Yanjun Wang, Alwin Schuller, Alexandra Borodovsky, Laura Prickett
Publikováno v:
Cancer Immunology Research. 8:A87-A87
Adenosine signaling via the adenosine 2A receptor (A2AR) is emerging as an important regulatory mechanism of immune responses. Adenosine levels are increased in the tumor microenvironment by the CD39/CD73 axis and adenosine signaling through the aden
Autor:
Carl Barrett, Alwin Schuller, Deanna A. Mele, Stephen Fawell, Kris Sachsenmeier, Laura Prickett, Yanjun Wang, Alexandra Borodovsky, Christine M. Barbon, Wenlin Shao
Publikováno v:
Cancer Research. 79:LB-192
Adenosine signaling is a normal physiologic process preventing autoimmunity, that is co-opted by tumors as an immune escape mechanism. Dendritic cells (DC), generated from human monocytes or mouse bone marrow, are susceptible to the immunosuppressive
Autor:
Radha Ramesh, Barbara S. Slusher, Gregory D. Wands, Min Yang, Thomas M. Luby, Mary Lynne Hedley, Christine M. Barbon
Publikováno v:
Cellular Immunology. 262:150-161
Cyclophosphamide in combination with immunotherapeutic approaches preferentially impinges on Treg activity and allows for robust generation of T cell effectors. Reduced dosages of cyclophosphamide are necessary to restrict its cytotoxic effects to th
Autor:
John M. McPherson, Anne Marie D’Angona, Robin J. Ziegler, Beth L. Thurberg, Seng H. Cheng, Laura Andrews, Christine M. Barbon, Edward H. Schuchman, Claire Brown, Kenneth P. Karey
Publikováno v:
Molecular Genetics and Metabolism. 97:35-42
Systemic administration of recombinant acid sphingomyelinase (rhASM) into ASM deficient mice (ASMKO) results in hydrolysis of the abnormal storage of sphingomyelin in lysosomes of the liver, spleen and lung. However, the efficiency with which the sub
Autor:
Eva C. Guinan, R. H. Kelner, Christine M. Barbon, Lisa L. Brennan, Jeff K. Davies, Lee M. Nadler, Annie R. Voskertchian
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 14(2)
Allostimulation with concurrent costimulatory blockade induces alloantigen-specific hyporesponsiveness in responder T cells ("alloanergization"). Alloanergized responder cells also acquire alloantigen-specific suppressive activity, suggesting this st