Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Christine M Will"'
Autor:
Relja Popovic, Eva Martinez-Garcia, Eugenia G Giannopoulou, Quanwei Zhang, Qingyang Zhang, Teresa Ezponda, Mrinal Y Shah, Yupeng Zheng, Christine M Will, Eliza C Small, Youjia Hua, Marinka Bulic, Yanwen Jiang, Matteo Carrara, Raffaele A Calogero, William L Kath, Neil L Kelleher, Ji-Ping Wang, Olivier Elemento, Jonathan D Licht
Publikováno v:
PLoS Genetics, Vol 10, Iss 9, p e1004566 (2014)
Overexpression of the histone methyltransferase MMSET in t(4;14)+ multiple myeloma patients is believed to be the driving factor in the pathogenesis of this subtype of myeloma. MMSET catalyzes dimethylation of lysine 36 on histone H3 (H3K36me2), and
Externí odkaz:
https://doaj.org/article/293a2a508f7f439b86ca58f29cbbee55
Autor:
Jonathan D. Licht, Richard B. Lock, Matthew D. Hall, Adolfo A. Ferrando, Richard L. Bennett, Alberto Riva, Min Shen, Christine M. Will, Jon A. Oyer, Marta Kulis, Alok Swaroop, Catalina Troche, Heidi L. Casellas Román, Duohui Jing, Jacob S. Roth, Daphne Dupéré-Richér, Crissandra Piper, Jonathan H. Shrimp, Julia Hlavka-Zhang, Jianping Li
Differentially expressed genes in NSD2 p.E1099K RCH-ACV cells with the change of H3K27me3 peaks
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a91870484950660f0812af4a109e7ed
https://doi.org/10.1158/2159-8290.22540601.v1
https://doi.org/10.1158/2159-8290.22540601.v1
Autor:
Jonathan D. Licht, Jan Liphardt, Alexander J. Ruthenburg, Neil L. Kelleher, George C. Schatz, Tanmay P. Lele, Alberto Riva, Qiao Zhang, Tao Yu, Adrian T. Grzybowski, Rajarshi P. Ghosh, Xiaoxiao Huang, Jon A. Oyer, Behnam Nabet, Christine M. Will, Eliza C. Small, Aditya Bele, Richard L. Bennett
List of all H4 missense mutations in cBioPortal nad dbSNP analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e1ec1be9e4c0e0f409ee2926f26c2b4
https://doi.org/10.1158/2159-8290.22535885
https://doi.org/10.1158/2159-8290.22535885
Supplementary Table 2: H2B from A Mutation in Histone H2B Represents a New Class of Oncogenic Driver
Autor:
Jonathan D. Licht, Jan Liphardt, Alexander J. Ruthenburg, Neil L. Kelleher, George C. Schatz, Tanmay P. Lele, Alberto Riva, Qiao Zhang, Tao Yu, Adrian T. Grzybowski, Rajarshi P. Ghosh, Xiaoxiao Huang, Jon A. Oyer, Behnam Nabet, Christine M. Will, Eliza C. Small, Aditya Bele, Richard L. Bennett
List of all H2B missense mutations in cBioPortal and dbSNP analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a42d432e63772deae6d95ad089c7c0b0
https://doi.org/10.1158/2159-8290.22535891
https://doi.org/10.1158/2159-8290.22535891
Autor:
Jonathan D. Licht, Jan Liphardt, Alexander J. Ruthenburg, Neil L. Kelleher, George C. Schatz, Tanmay P. Lele, Alberto Riva, Qiao Zhang, Tao Yu, Adrian T. Grzybowski, Rajarshi P. Ghosh, Xiaoxiao Huang, Jon A. Oyer, Behnam Nabet, Christine M. Will, Eliza C. Small, Aditya Bele, Richard L. Bennett
List of all H3 missense mutations in cBioPortal and dbSNP analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e967773c98ae5ef8365cd2bff0f4d38
https://doi.org/10.1158/2159-8290.22535888.v1
https://doi.org/10.1158/2159-8290.22535888.v1
Autor:
Jonathan D. Licht, Jan Liphardt, Alexander J. Ruthenburg, Neil L. Kelleher, George C. Schatz, Tanmay P. Lele, Alberto Riva, Qiao Zhang, Tao Yu, Adrian T. Grzybowski, Rajarshi P. Ghosh, Xiaoxiao Huang, Jon A. Oyer, Behnam Nabet, Christine M. Will, Eliza C. Small, Aditya Bele, Richard L. Bennett
Supplemental materials and methods and Supplemental Figures 1-7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26fa2f765d8faaf9da739e819ca0eebf
https://doi.org/10.1158/2159-8290.22535897.v1
https://doi.org/10.1158/2159-8290.22535897.v1
Supplementary Table 1: H2A from A Mutation in Histone H2B Represents a New Class of Oncogenic Driver
Autor:
Jonathan D. Licht, Jan Liphardt, Alexander J. Ruthenburg, Neil L. Kelleher, George C. Schatz, Tanmay P. Lele, Alberto Riva, Qiao Zhang, Tao Yu, Adrian T. Grzybowski, Rajarshi P. Ghosh, Xiaoxiao Huang, Jon A. Oyer, Behnam Nabet, Christine M. Will, Eliza C. Small, Aditya Bele, Richard L. Bennett
List of all H2A missense mutations in cBioPortal and dbSNP analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::234f63b7625220384d4229954f672077
https://doi.org/10.1158/2159-8290.22535894
https://doi.org/10.1158/2159-8290.22535894
Autor:
Jonathan D. Licht, Richard B. Lock, Matthew D. Hall, Adolfo A. Ferrando, Richard L. Bennett, Alberto Riva, Min Shen, Christine M. Will, Jon A. Oyer, Marta Kulis, Alok Swaroop, Catalina Troche, Heidi L. Casellas Román, Duohui Jing, Jacob S. Roth, Daphne Dupéré-Richér, Crissandra Piper, Jonathan H. Shrimp, Julia Hlavka-Zhang, Jianping Li
Supplementary Methods and Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f527e42d7609e21d0ce6a0dc9cd8297f
https://doi.org/10.1158/2159-8290.22540619.v1
https://doi.org/10.1158/2159-8290.22540619.v1
Autor:
Jonathan D. Licht, Richard B. Lock, Matthew D. Hall, Adolfo A. Ferrando, Richard L. Bennett, Alberto Riva, Min Shen, Christine M. Will, Jon A. Oyer, Marta Kulis, Alok Swaroop, Catalina Troche, Heidi L. Casellas Román, Duohui Jing, Jacob S. Roth, Daphne Dupéré-Richér, Crissandra Piper, Jonathan H. Shrimp, Julia Hlavka-Zhang, Jianping Li
Mutations in epigenetic regulators are common in relapsed pediatric acute lymphoblastic leukemia (ALL). Here, we uncovered the mechanism underlying the relapse of ALL driven by an activating mutation of the NSD2 histone methyltransferase (p.E1099K).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74d81e3bd352ab69e448030a91c43dd4
https://doi.org/10.1158/2159-8290.c.6549425.v1
https://doi.org/10.1158/2159-8290.c.6549425.v1
Autor:
Jonathan D. Licht, Jan Liphardt, Alexander J. Ruthenburg, Neil L. Kelleher, George C. Schatz, Tanmay P. Lele, Alberto Riva, Qiao Zhang, Tao Yu, Adrian T. Grzybowski, Rajarshi P. Ghosh, Xiaoxiao Huang, Jon A. Oyer, Behnam Nabet, Christine M. Will, Eliza C. Small, Aditya Bele, Richard L. Bennett
By examination of the cancer genomics database, we identified a new set of mutations in core histones that frequently recur in cancer patient samples and are predicted to disrupt nucleosome stability. In support of this idea, we characterized a gluta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::802e019e6317e5fbaeb79369473efa1a
https://doi.org/10.1158/2159-8290.c.6547973.v1
https://doi.org/10.1158/2159-8290.c.6547973.v1