Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Christine M Solinsky"'
Autor:
Gerson D. Hernandez, Christine M. Solinsky, Wendy J. Mack, Naoko Kono, Kathleen E. Rodgers, Chun‐Yi Wu, Ana R. Mollo, Claudia M. Lopez, Sonia Pawluczyk, Gerhard Bauer, Dawn Matthews, Yonggang Shi, Meng Law, Michael A. Rogawski, Lon S. Schneider, Roberta D. Brinton
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 6, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction Allopregnanolone is an endogenous neurosteroid with the potential to be a novel regenerative therapeutic for Alzheimer's disease (AD). Foundations of mechanistic understanding and well‐established preclinical safety efficacy m
Externí odkaz:
https://doaj.org/article/5850674a3da74dfebad3206ffcd3f5dc
Autor:
Rajiv Agarwal, Sanjeev Anand, Kai-Uwe Eckardt, Wenli Luo, Patrick S. Parfrey, Mark J. Sarnak, Christine M. Solinsky, Dennis L. Vargo, Wolfgang C. Winkelmayer, Glenn M. Chertow
Publikováno v:
American Journal of Nephrology. 53:701-710
Introduction: Anemia frequently occurs in chronic kidney disease (CKD), is associated with poor quality of life and cardiovascular outcomes, and its treatment represents a considerable economic burden to the healthcare system. Although effective, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ae1f880da6d02e2bd5d17d73f397c79
https://doi.org/10.1159/000528443
https://doi.org/10.1159/000528443
Autor:
Ronald W Irwin, Christine M Solinsky, Carlos M Loya, Francesco G Salituro, Kathleen E Rodgers, Gerhard Bauer, Michael A Rogawski, Roberta Diaz Brinton
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128313 (2015)
To develop allopregnanolone as a therapeutic for Alzheimer's disease, we investigated multiple formulations and routes of administration in translationally relevant animal models of both sexes. Subcutaneous, topical (transdermal and intranasal), intr
Externí odkaz:
https://doaj.org/article/040fc371d0ab4f1ca16b64dd413384d7
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 8 (2014)
Allopregnanolone (Allo), a neurosteroid, has emerged as a promising promoter of endogenous regeneration in brain. In a mouse model of Alzheimer’s disease, Allo induced neurogenesis, oligodendrogenesis, white matter generation and cholesterol homeos
Externí odkaz:
https://doaj.org/article/5df76ff417d645d289d651c55a123122
Autor:
Meng Law, Chun-Yi Wu, Gerhard Bauer, Naoko Kono, Roberta Diaz Brinton, Kathleen E. Rodgers, Sonia Pawluczyk, Michael A. Rogawski, Yonggang Shi, Lon S. Schneider, Gerson D. Hernandez, Wendy J. Mack, Claudia M. Lopez, Christine M. Solinsky, Ana R. Mollo, Dawn C. Matthews
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 6, Iss 1, Pp n/a-n/a (2020)
Alzheimer's & Dementia : Translational Research & Clinical Interventions
Alzheimer's & dementia (New York, N. Y.), vol 6, iss 1
Alzheimer's & Dementia : Translational Research & Clinical Interventions
Alzheimer's & dementia (New York, N. Y.), vol 6, iss 1
IntroductionAllopregnanolone is an endogenous neurosteroid with the potential to be a novel regenerative therapeutic for Alzheimer's disease (AD). Foundations of mechanistic understanding and well-established preclinical safety efficacy make it a via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7a72e1a800aa86cfaff396ae92788c7
https://doi.org/10.1002/trc2.12107
https://doi.org/10.1002/trc2.12107
Autor:
Roberta Diaz Brinton, Yiwei Wang, Christine M. Solinsky, Gerson D. Hernandez, Lon S. Schneider
Publikováno v:
Alzheimer's & Dementia. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46dd8bf59490268f04c8ceeed3633dde
https://doi.org/10.1016/j.jalz.2018.06.019
https://doi.org/10.1016/j.jalz.2018.06.019
Autor:
Mathew Blurton-Jones, Christine M. Solinsky, Justin K. Ichida, Roberta Diaz Brinton, Helena C. Chui, Jenny Ayoung Park
Publikováno v:
Alzheimer's & Dementia. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e667cab6e9490079401c371913f185e
https://doi.org/10.1016/j.jalz.2017.06.1379
https://doi.org/10.1016/j.jalz.2017.06.1379
Autor:
Naoko Kono, Gerson D. Hernandez, Lon S. Schneider, Roberta Diaz Brinton, Claudia Lopez, Wendy J. Mack, Christine M. Solinsky, Ronald W. Irwin
Publikováno v:
Alzheimer's & Dementia. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be72ae061261e4a11c1700d91ab2a37e
https://doi.org/10.1016/j.jalz.2017.06.1884
https://doi.org/10.1016/j.jalz.2017.06.1884
Autor:
Lon S. Schneider, Gerson D. Hernandez, Roberta Diaz Brinton, Yiwei Wang, Christine M. Solinsky
Publikováno v:
Alzheimer's & Dementia. 15:P938-P938
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17ed7f9dbc563234f852df38471f7718
https://doi.org/10.1016/j.jalz.2019.06.3058
https://doi.org/10.1016/j.jalz.2019.06.3058
Autor:
Gerhard Bauer, Ronald W. Irwin, Michael A. Rogawski, Kathleen E. Rodgers, Roberta Diaz Brinton, Christine M. Solinsky
Publikováno v:
Alzheimer's & Dementia. 12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e54d30b94d7ed73ec1d72aaa21877e23
https://doi.org/10.1016/j.jalz.2016.06.820
https://doi.org/10.1016/j.jalz.2016.06.820