Etiology of severe invasive infections in young infants in rural settings in sub-Saharan Africa.

Autor: Estomih Mduma, Tinto Halidou, Berenger Kaboré, Thomas Walongo, Palpouguini Lompo, Justine Museveni, Joshua Gidabayda, Jean Gratz, Godfrey Guga, Caroline Kimathi, Jie Liu, Paschal Mdoe, Robert Moshiro, Max Petzold, Jan Singlovic, Martine Guillerm, Melba F Gomes, Eric R Houpt, Christine M Halleux

Publikováno v: PLoS ONE, Vol 17, Iss 2, p e0264322 (2022)

BackgroundSerious invasive infections in newborns are a major cause of death. Lack of data on etiological causes hampers progress towards reduction of mortality. This study aimed to identify pathogens responsible for such infections in young infants

Externí odkaz: https://doaj.org/article/a0469669d6074e78b0d53248dfbf5cea

A call to action for universal health coverage: Why we need to address gender inequities in the neglected tropical diseases community.

Autor: Kim Ozano, Laura Dean, Mami Yoshimura, Eleanor MacPherson, Natalia Linou, Mariam Otmani Del Barrio, Christine M Halleux, Olumide Ogundahunsi, Sally Theobald

Publikováno v: PLoS Neglected Tropical Diseases, Vol 14, Iss 3, p e0007786 (2020)

Externí odkaz: https://doaj.org/article/3e693874acb54923a831727daa1ad0f5

Onchocerca volvulus microfilariae in the anterior chambers of the eye and ocular adverse events after a single dose of 8 mg moxidectin or 150 µg/kg ivermectin: results of a randomized double-blind Phase 3 trial in the Democratic Republic of the Congo, Ghana and Liberia

Autor: Eric M. Kanza, Amos Nyathirombo, Jemmah P. Larbelee, Nicholas O. Opoku, Didier K. Bakajika, Hayford M. Howard, Germain L. Mambandu, Maurice M. Nigo, Deogratias Ucima Wonyarossi, Françoise Ngave, Kambale Kasonia Kennedy, Kambale Kataliko, Kpehe M. Bolay, Simon K. Attah, George Olipoh, Sampson Asare, Mupenzi Mumbere, Michel Vaillant, Christine M. Halleux, Annette C. Kuesel

Publikováno v: Parasites & Vectors, Vol 17, Iss 1, Pp 1-23 (2024)

Abstract Background After ivermectin became available, diethylcarbamazine (DEC) use was discontinued because of severe adverse reactions, including ocular reactions, in individuals with high Onchocerca volvulus microfilaridermia (microfilariae/mg ski

Externí odkaz: https://doaj.org/article/4ceb592513504c51851aa39437b4b9bd

Effectiveness of seasonal malaria chemoprevention at scale in west and central Africa: an observational study

Autor: Rhosyn Tuta, Houda Sefiani, Mariama Sire Sano, Jean Louis NdDiaye, Diakalidia Kone, Maddy Marasciulo, Paul Snell, Matthew Cairns, Lantorina Razafindralambo, Rahila Abdoulaye, Sonny Johnbull Ogboi, Kovana Marcel Loua, Momodou Kalleh, Julian Muwanguzi, Ibrahim Laminou, Rebecca F. Grais, Tony Eloike, Serign J. Ceesay, Aishatu Yinusa Cassandra Elagbaje, Harriet Kivumbi, Kalifa Bojang, Alice Kiba, Issaka Zongo, Halimatou Alassana Messan, Ebenezer Baba, Rachida Souleymani, Moussa Keita, Ibrahim Ouba, Susana Scott, Nadine Ngarnaye, Matt Coldiron, Yacine Djibo, Abdoulaye Djimde, Gladys Tetteh, Hadiza Jackou, Djiddi Ali Sougoudi, George Jagoe, Abdoulaye Hama Diallo, Kolawole Maxwell, Daugla Doumagoum, Issaka Sagara, Eric Hubbard, Hamit Kesseley, Emile Ouedraogo, André-Marie Tchouatieu, Musa Abubakar Kana, Khalid B. Beshir, Godwin Ntadom, Fatou Jah, Eugene Kaman Lama, Alassane Dicko, Colin J. Sutherland, Jean-Bosco Ouédraogo, Shanthi N. Pal, Markieu Janneh Kaira, Fara Ndiaye, Corinne Merle, Prudence Hamade, Kodbesse Boulotigam, James K Tibenderana, Timothee Guilavogui, Sham Lal, Noha Iessa, Paul Milligan, Jane Achan, Yolanda Fernandez, Raoul Mansukhani, Suzanne Van Hulle, Huja Jah, Colin Gilmartin, Arantxa Roca-Feltrer, Mamadou Chérif Traore, Bala Audu, Diego Moroso, David Collins, Joanna Stenstrom Johansson, Yacouba Savodogo, Balla Kandeh, Christine M Halleux, Adama Sanogo, Patrice Coulibaly

Publikováno v: Lancet (London, England)

Summary Background Seasonal malaria chemoprevention (SMC) aims to prevent malaria in children during the high malaria transmission season. The Achieving Catalytic Expansion of SMC in the Sahel (ACCESS-SMC) project sought to remove barriers to the sca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fd023d3a0d31a2fd7843cf9a39093fd
https://pubmed.ncbi.nlm.nih.gov/33278921

Hormonal Control of Plasminogen Activator Inhibitor-1 Gene Expression and Production in Human Adipose Tissue: Stimulation by Glucocorticoids and Inhibition by Catecholamines1

Autor: Sonia Brichard, Sinh L Tran, Roger Detry, Christine M Halleux, Paul Declerck

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 84:4097-4105

Plasma levels of type 1 plasminogen activator inhibitor (PAI-1), a risk factor for cardiovascular disease, are elevated in obese subjects, especially those with omental fat accumulation. We investigated the hormonal control of PAI-1 gene expression a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5b80507b55736a3f7ff4f2e4078653e5
https://doi.org/10.1210/jcem.84.11.6127