Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Christine M Cross"'
Autor:
Kirsty L Brain, Beth J Allison, Youguo Niu, Christine M Cross, Nozomi Itani, Andrew D Kane, Emilio A Herrera, Katie L Skeffington, Kimberley J Botting, Dino A Giussani
Publikováno v:
PLoS Biology, Vol 17, Iss 1, p e2006552 (2019)
Evidence derived from human clinical studies and experimental animal models shows a causal relationship between adverse pregnancy and increased cardiovascular disease in the adult offspring. However, translational studies isolating mechanisms to desi
Externí odkaz:
https://doaj.org/article/891649ff31054c8eac304daa17a68641
Autor:
Dino A Giussani, Emily J Camm, Youguo Niu, Hans G Richter, Carlos E Blanco, Rachel Gottschalk, E Zachary Blake, Katy A Horder, Avnesh S Thakor, Jeremy A Hansell, Andrew D Kane, F B Peter Wooding, Christine M Cross, Emilio A Herrera
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31017 (2012)
Fetal hypoxia is a common complication of pregnancy. It has been shown to programme cardiac and endothelial dysfunction in the offspring in adult life. However, the mechanisms via which this occurs remain elusive, precluding the identification of pot
Externí odkaz:
https://doaj.org/article/f60f356a30ad4578bc932739c66d2742
Autor:
Emily J Camm, Deodata Tijsseling, Hans G Richter, Alexandra Adler, Jeremy A Hansell, Jan B Derks, Christine M Cross, Dino A Giussani
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21142 (2011)
In premature infants, glucocorticoids ameliorate chronic lung disease, but have adverse effects on long-term neurological function. Glucocorticoid excess promotes free radical overproduction. We hypothesised that the adverse effects of postnatal gluc
Externí odkaz:
https://doaj.org/article/b4669f73acf345a7924536d5842e6314
Autor:
Emily J. Camm, Andrew D. Kane, Dino A. Giussani, Susan E. Ozanne, Jane L. Tarry-Adkins, Christine M. Cross
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 35(5)
Chronic fetal hypoxia is one of the most common outcomes in complicated pregnancy in humans. Despite this, its effects on the long‐term health of the brain in offspring are largely unknown. Here, we investigated in rats whether hypoxic pregnancy af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a120e2a8877a9fdfe7e638fdf639b57
https://pubmed.ncbi.nlm.nih.gov/33891326
https://pubmed.ncbi.nlm.nih.gov/33891326
Autor:
Chritian Beck, Avnesh S. Thakor, Emilio A. Herrera, Nozomi Itani, Caroline J. Shaw, Katie L. Skeffington, Kirsty L. Brain, Dino A. Giussani, Kimberley J. Botting, Christine M. Cross, Andrew D. Kane, Youguo Niu, Beth J. Allison
Publikováno v:
Hypertension (Dallas, Tex. : 1979)
Supplemental Digital Content is available in the text.
The hypoxic fetus is at greater risk of cardiovascular demise during a challenge, but the reasons behind this are unknown. Clinically, progress has been hampered by the inability to study th
The hypoxic fetus is at greater risk of cardiovascular demise during a challenge, but the reasons behind this are unknown. Clinically, progress has been hampered by the inability to study th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::363056456a64391da2981abfb2db8233
https://pubmed.ncbi.nlm.nih.gov/32862711
https://pubmed.ncbi.nlm.nih.gov/32862711
Autor:
Willem B. de Vries, Deodata Tijsseling, Andrew D. Kane, Christine M. Cross, Dino A. Giussani, Emily J. Camm, Emilio A. Herrera, Jan B. Derks, Hans Richter, Youguo Niu
Publikováno v:
Pediatric Research. 74:639-645
Postnatal glucocorticoid therapy in the treatment of chronic lung disease benefits lung function, however it adversely affects brain development. We hypothesized that combined postnatal glucocorticoid and statin therapy diminishes adverse effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffc65ef854ff9d1cc0aa9a30e2adba24
https://doi.org/10.1038/pr.2013.152
https://doi.org/10.1038/pr.2013.152
Autor:
Roger Foo, Heather L. Blackmore, Christine M. Cross, Susan E. Ozanne, Lee Siggens, Denise S. Fernandez-Twinn, Dino A. Giussani
Publikováno v:
Endocrinology
Human and animal studies suggest that suboptimal early nutrition during critical developmental periods impacts long-term health. For example, maternal overnutrition during pregnancy and lactation in mice programs insulin resistance, obesity, and endo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498465d2c6cdd6fe8740d3707f84cf31
https://doi.org/10.1210/en.2012-1508
https://doi.org/10.1210/en.2012-1508
Ascorbate prevents placental oxidative stress and enhances birth weight in hypoxic pregnancy in rats
Autor:
B. N. Modi, Hans Richter, Frank J. Kelly, Ian Mudway, Christine M. Cross, Dino A. Giussani, F. Naeem, Emily J. Camm, Graham J. Burton, Tereza Cindrova-Davies, Olivera Spasic-Boskovic, Lucilla Poston, Christina Dunster
Publikováno v:
The Journal of Physiology. 590:1377-1387
This study isolated the effects of maternal hypoxia independent of changes in maternal nutrition on maternal circulatory and placental molecular indices of oxidative stress and determined whether maternal antioxidant treatment conferred protection. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63fa7f51cb039eca53eefafa424fe320
https://doi.org/10.1113/jphysiol.2011.226340
https://doi.org/10.1113/jphysiol.2011.226340
Autor:
Dino A, Giussani, Youguo, Niu, Emilio A, Herrera, Hans G, Richter, Emily J, Camm, Avnesh S, Thakor, Andrew D, Kane, Jeremy A, Hansell, Kirsty L, Brain, Katie L, Skeffington, Nozomi, Itani, F B Peter, Wooding, Christine M, Cross, Beth J, Allison
Publikováno v:
Advances in experimental medicine and biology. 814
The quality of the intrauterine environment interacts with our genetic makeup to shape the risk of developing disease in later life. Fetal chronic hypoxia is a common complication of pregnancy. This chapter reviews how fetal chronic hypoxia programme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f920d0b36e6c1837285e9216c2d4e6af
https://pubmed.ncbi.nlm.nih.gov/25015802
https://pubmed.ncbi.nlm.nih.gov/25015802
Autor:
Emily J. Camm, Carlos E. Blanco, F. B. Peter Wooding, Hans Richter, Jeremy A. Hansell, E. Zachary Blake, Avnesh S. Thakor, Katy A. Horder, Youguo Niu, Dino A. Giussani, Rachel Gottschalk, Emilio A. Herrera, Christine M. Cross, Andrew D. Kane
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31017 (2012)
PLoS ONE
PLoS ONE
Fetal hypoxia is a common complication of pregnancy. It has been shown to programme cardiac and endothelial dysfunction in the offspring in adult life. However, the mechanisms via which this occurs remain elusive, precluding the identification of pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::979f24aeb68b18a0cb9d7294805e07e6
https://www.repository.cam.ac.uk/handle/1810/310035
https://www.repository.cam.ac.uk/handle/1810/310035
