Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Christine M, Sorenson"'
Autor:
Christine M Sorenson, Zafer Gurel, Yong-Seok Song, Kyle D Peterson, Barbara A Blodi, Nader Sheibani
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0297135 (2024)
Age-related macular degeneration (AMD) is a vision threatening disease in older adults. Anti-VEGF treatment is effective for the majority of neovascular AMD (nAMD) patients, although approximately 30% of nAMD patients have an incomplete response for
Externí odkaz:
https://doaj.org/article/aac38f7c859d491182daf612a28022c1
Publikováno v:
Frontiers in Ophthalmology, Vol 4 (2024)
Externí odkaz:
https://doaj.org/article/cc53c0666837423daaf652dac96331eb
Publikováno v:
Cells, Vol 13, Iss 1, p 50 (2023)
Age-related macular degeneration (AMD) remains a leading cause of vision loss in elderly patients. Its etiology and progression are, however, deeply intertwined with various cellular and molecular interactions within the retina and choroid. Among the
Externí odkaz:
https://doaj.org/article/29c777ec284b4569bd925e116556078b
Autor:
Collin P. Goebel, Yong-Seok Song, Ismail S. Zaitoun, Shoujian Wang, Heather A. D. Potter, Christine M. Sorenson, Nader Sheibani
Publikováno v:
Journal of Ophthalmic & Vision Research, Vol 18, Iss 1, Pp 1-2 (2023)
Abstract Purpose: Adenosine signaling modulates ocular inflammatory processes, and its antagonism mitigates neovascularization in both newborns and preclinical models of ocular neovascularization including age-related macular degeneration (AMD). The
Externí odkaz:
https://doaj.org/article/c924fab79dc843118d8057f506cd15ed
Autor:
Ismail S. Zaitoun, Pawan K. Shahi, Andrew Suscha, Kore Chan, Gillian J. McLellan, Bikash R. Pattnaik, Christine M. Sorenson, Nader Sheibani
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Ischemic stroke is a major cause of long-term disabilities, including vision loss. Neuronal and blood vessel maturation can affect the susceptibility of and outcome after ischemic stroke. Although we recently reported that exposure of neonat
Externí odkaz:
https://doaj.org/article/defc15708d154c2694a7566ad8ecf618
Publikováno v:
Cells, Vol 12, Iss 2, p 335 (2023)
The integrity of retinal endothelial cell (EC) is essential for establishing and maintaining the retinal blood barrier to ensure proper vision. Vitamin D is a hormone with known protective roles in EC function. The majority of vitamin D action is med
Externí odkaz:
https://doaj.org/article/1707305b29f048aab833474b6861d96c
Autor:
Christine M. Sorenson, Yong-Seok Song, Ismail S. Zaitoun, Shoujian Wang, Barbara A. Hanna, Soesiawati R. Darjatmoko, Zafer Gurel, Debra L. Fisk, Colleen M. McDowell, Ryan M. McAdams, Nader Sheibani
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Adenosine receptors (AR) are widely expressed in a variety of tissues including the retina and brain. They are involved in adenosine-mediated immune responses underlying the onset and progression of neurodegenerative diseases. The expression of AR ha
Externí odkaz:
https://doaj.org/article/02459f7142584f92902c60fc09be27df
Assessment of Choroidal Vasculature and Innate Immune Cells in the Eyes of Albino and Pigmented Mice
Publikováno v:
Cells, Vol 11, Iss 20, p 3329 (2022)
The visualization of choroidal vasculature and innate immune cells in the eyes of pigmented mice has been challenging due to the presence of a retinal pigment epithelium (RPE) layer separating the choroid and retina. Here, we established methods for
Externí odkaz:
https://doaj.org/article/a3d27e259e6b496d96a45a9540c124de
Autor:
Ismail S. Zaitoun, Catherine M. Wintheiser, Nasim Jamali, Shoujian Wang, Andrew Suscha, Soesiawati R. Darjatmoko, Katherine Schleck, Barbara A. Hanna, Volkhard Lindner, Nader Sheibani, Christine M. Sorenson
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Abstract B-cell lymphoma 2 (Bcl-2) protein is the founding member of a group of proteins known to modulate apoptosis. Its discovery set the stage for identification of family members with either pro- or anti-apoptotic properties. Expression of Bcl-2
Externí odkaz:
https://doaj.org/article/718ad2e315fb4f21a2f96f996666b937
Publikováno v:
FASEB BioAdvances, Vol 1, Iss 7, Pp 415-434 (2019)
Abstract We have previously demonstrated that the active form of vitamin D (calcitriol; 1,25(OH)2D3) is a potent inhibitor of retinal neovascularization. However, the underlying molecular and cellular mechanisms involved remained poorly understood. P
Externí odkaz:
https://doaj.org/article/793d689a6c044ca6a9eb18f6cdf34b76