Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Christine M, Shortt"'
Autor:
F. Markos, Oliviero L. Gobbo, Elaine Barry, Mohammed H. Abdulla, Christine M. Shortt, Deirdre Edge, Edward J. Johns
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 95:443-446
A recent study showed that a significant fall in mean arterial pressure (MAP) occurred following intravenous injection of two novel superparamagnetic iron oxide nanoparticles (SPIONs), MF66 and OD15. To assess if this was caused by excessive glomerul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bf440131bbbede91fa66fce85c866af
https://doi.org/10.1139/cjpp-2016-0405
https://doi.org/10.1139/cjpp-2016-0405
Autor:
Peter MacEneaney, Adriele Prina-Mello, Yuri Volkov, F. Markos, Deirdre Edge, Marek W. Radomski, Stéphanie Teughels, Oliviero L. Gobbo, Christine M. Shortt
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 43:319-326
Manufactured nanomaterials have a variety of medical applications, including diagnosis and targeted treatment of cancer. A series of experiments were conducted to determine the pharmacokinetic, biodistribution and biocompatibility of two novel magnet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54b699b55877ea51677574cc4a352660
https://doi.org/10.1111/1440-1681.12533
https://doi.org/10.1111/1440-1681.12533
Autor:
F. Markos, Kieran Crosbie-Staunton, Deirdre Edge, Adriele Prina-Mello, Friedrich Wetterling, Marek W. Radomski, Stéphanie Teughels, Peter Vaes, Oliviero L. Gobbo, Christine M. Shortt, Yuri Volkov
Publikováno v:
Nanomedicine. 10:1751-1760
Aim: Superparamagnetic iron oxide nanoparticles (SPIONs) may play an important role in nanomedicine by serving as drug carriers and imaging agents. In this study, we present the biodistribution and pharmacokinetic properties of SPIONs using a new det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d6131b1bb2bba09deee71d2557e0f12
https://doi.org/10.2217/nnm.15.22
https://doi.org/10.2217/nnm.15.22
Autor:
Anne Fredsted, Christine M. Shortt, Ken D. O'Halloran, Han Bing Chow, Deirdre Edge, J. Richard Skelly, Aidan Bradford, Robert Williams
Publikováno v:
Experimental Physiology. 99:688-700
Respiratory muscle dysfunction documented in sleep apnoea patients is perhaps due to oxidative stress secondary to chronic intermittent hypoxia (CIH). We sought to explore the effects of different CIH protocols on respiratory muscle form and function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bae2997cbf9efc19cb8cc73a4e71f6e0
https://doi.org/10.1113/expphysiol.2013.076828
https://doi.org/10.1113/expphysiol.2013.076828
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 91:1031-1036
The effect of intraluminal hyperglycaemia was investigated in the iliac artery of 11 anaesthetised pigs. Following isolation of a test segment, hyperglycaemic blood (40 mmol·L–1) caused a significant dilatation of the artery of 167 ± 208 μm (mea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4ea0083bffc3c82f034f8a1e8c45ef4
https://doi.org/10.1139/cjpp-2013-0206
https://doi.org/10.1139/cjpp-2013-0206
Publikováno v:
Shortt, C M, Fredsted, A, Bradford, A & O'Halloran, K D 2013, ' Diaphragm Muscle Remodeling in a Rat Model of Chronic Intermittent Hypoxia ', Journal of Histochemistry and Cytochemistry, vol. 61, no. 7, pp. 487-499 . https://doi.org/10.1369/0022155413490947
Respiratory muscle remodeling occurs in human sleep apnea—a common respiratory disorder characterized by chronic intermittent hypoxia (CIH) due to recurrent apnea during sleep. We sought to determine if CIH causes remodeling in rat sternohyoid (upp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fddb916a4bb4ff86730969433395e68a
https://doi.org/10.1369/0022155413490947
https://doi.org/10.1369/0022155413490947
Autor:
Christine M. Shortt, Deirdre Edge, J. Richard Skelly, Aidan Bradford, Ken D. O'Halloran, James F. X. Jones
Publikováno v:
Respiratory Physiology & Neurobiology. 180:175-182
Obstructive sleep apnoea syndrome (OSAS) is a common respiratory disorder characterized by chronic intermittent hypoxia (CIH). We have shown that CIH causes upper airway muscle dysfunction in the rat due to oxidative stress. Ageing is an independent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a28d3274565091a03b0f6e5882774f6
https://doi.org/10.1016/j.resp.2011.11.004
https://doi.org/10.1016/j.resp.2011.11.004
Publikováno v:
Physiological research. 63(5)
Elevated levels of insulin have been reported to induce both an arterial vasodilation mediated by nitric oxide (NO), and vasoconstriction mediated by endothelin and reactive oxygen radicals. Metformin, used to control blood glucose levels in type 2 d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de247e5a48f296fd32929edb8162ed70
https://pubmed.ncbi.nlm.nih.gov/24908091
https://pubmed.ncbi.nlm.nih.gov/24908091
Publikováno v:
The FASEB Journal. 28
With a growing number of applications associated with nanostructures, characterization in-vivo is imperative. Previous MRI studies have described the accumulation of SPION’s in the rat and pig kidn...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54419466ed0420fcea1313cc3024d834
https://doi.org/10.1096/fasebj.28.1_supplement.lb730
https://doi.org/10.1096/fasebj.28.1_supplement.lb730
Autor:
Oliviero L. Gobbo, Stéphanie Teughels, Adriele Prina-Mello, Deirdre Edge, Yuri Volkov, Christine M. Shortt, Joeri Verbiest, F. Markos, Eric Roskin
Publikováno v:
The FASEB Journal. 28
Manufactured nanomaterials have been shown to be beneficial in an array of applications, including diagnosis and targeted abolition of tumour cells. The biocompatibility and bio-distribution of the...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7333987016d1f4c5812416b2045b645
https://doi.org/10.1096/fasebj.28.1_supplement.lb578
https://doi.org/10.1096/fasebj.28.1_supplement.lb578