Výsledky vyhledávání - "Christine Lindsay Mummery"

Maturation of hiPSC-derived cardiomyocytes promotes adult alternative splicing of SCN5A and reveals changes in sodium current associated with cardiac arrhythmia

Autor: Giulia Campostrini, Georgios Kosmidis, Dorien Ward-van Oostwaard, Richard Paul Davis, Loukia Yiangou, Daniele Ottaviani, Christiaan Cornelis Veerman, Hailiang Mei, Valeria Viktorovna Orlova, Arthur Arnold Maria Wilde, Connie Rose Bezzina, Arie Otto Verkerk, Christine Lindsay Mummery, Milena Bellin

Publikováno v: Cardiovascular Research. OXFORD UNIV PRESS
Cardiovascular Research
Cardiovascular research, 119(1), 167-182. Oxford University Press

Aims Human-induced pluripotent stem cell-cardiomyocytes (hiPSC-CMs) are widely used to study arrhythmia-associated mutations in ion channels. Among these, the cardiac sodium channel SCN5A undergoes foetal-to-adult isoform switching around birth. Conv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ec6e99e1702311977874cf0d6bc0cb8
http://hdl.handle.net/1887/3561420

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