Zobrazeno 1 - 10
of 429
pro vyhledávání: '"Christine Lehmann"'
Autor:
Dunja Tutus, Mandy Niemitz, Paul L. Plener, Jörg M. Fegert, Christine Lehmann, Christa Weiss, Christine Knaevelsrud, Lisa Biehl, Miriam Rassenhofer
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-14 (2024)
Abstract Background Approximately 50% of rare diseases have symptom onset during childhood. A high level of nursing care and an often uncertain prognosis put caregivers of the affected children at high risk for psychological distress. At the same tim
Externí odkaz:
https://doaj.org/article/afb8ccb46c8949a1b8195dd1f90bab23
Autor:
Sabine Wiegmann, Martina Ernst, Loretta Ihme, Katja Wechsung, Ute Kalender, Barbara Stöckigt, Annette Richter-Unruh, Sander Vögler, Olaf Hiort, Martina Jürgensen, Louise Marshall, Ingo Menrath, Julia Schneidewind, Isabel Wagner, Julia Rohayem, Klaus-Peter Liesenkötter, Martin Wabitsch, Malaika Fuchs, Gloria Herrmann, Henriette Lutter, Gundula Ernst, Christine Lehmann, Martina Haase, Stephanie Roll, Ralph Schilling, Thomas Keil, Uta Neumann
Publikováno v:
BMC Endocrine Disorders, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background Differences in sexual development (DSD) are rare diseases, which affect the chromosomal, anatomical or gonadal sex differentiation. Although patient education is recommended as essential in a holistic care approach, standardised p
Externí odkaz:
https://doaj.org/article/665174da0b424cea88160122ba0dfe0a
Autor:
Linus Piehler, Ralf Thalemann, Christine Lehmann, Stephanie Thee, Jobst Röhmel, Zulfiya Syunyaeva, Mirjam Stahl, Marcus A. Mall, Simon Y. Graeber
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: The CFTR modulator drug elexacaftor/tezacaftor/ivacaftor (ETI) was shown to improve CFTR function and clinical symptoms in patients with cystic fibrosis (CF) with at least one F508del allele. Recently, some case reports suggested potent
Externí odkaz:
https://doaj.org/article/7ae8a967ccd34950a7f3cc31a5ca7a99
Autor:
Mateo I Sanchez, Laura E de Vries, Christine Lehmann, Jeong T Lee, Kenny K Ang, Christopher Wilson, Steven Chen, Michelle R Arkin, Matthew Bogyo, Edgar Deu
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0226270 (2019)
Dipeptidyl aminopeptidases (DPAPs) are cysteine proteases that cleave dipeptides from the N-terminus of protein substrates and have been shown to play important roles in many pathologies including parasitic diseases such as malaria, toxoplasmosis and
Externí odkaz:
https://doaj.org/article/bf56062846c6498e9b0850535a2beef1
Autor:
Christine Lehmann, Michele Ser Ying Tan, Laura E de Vries, Ilaria Russo, Mateo I Sanchez, Daniel E Goldberg, Edgar Deu
Publikováno v:
PLoS Pathogens, Vol 14, Iss 5, p e1007031 (2018)
Parasite egress from infected erythrocytes and invasion of new red blood cells are essential processes for the exponential asexual replication of the malaria parasite. These two tightly coordinated events take place in less than a minute and are in p
Externí odkaz:
https://doaj.org/article/aecef49ea2354e8ab088dc947a670680
Autor:
Christine S Hopp, Brandy L Bennett, Satish Mishra, Christine Lehmann, Kirsten K Hanson, Jing-Wen Lin, Kimberly Rousseau, Filomena A Carvalho, Wouter A van der Linden, Nuno C Santos, Matthew Bogyo, Shahid M Khan, Volker Heussler, Photini Sinnis
Publikováno v:
PLoS Pathogens, Vol 13, Iss 9, p e1006586 (2017)
Proteases have been implicated in a variety of developmental processes during the malaria parasite lifecycle. In particular, invasion and egress of the parasite from the infected hepatocyte and erythrocyte, critically depend on protease activity. Alt
Externí odkaz:
https://doaj.org/article/89689e3f69b94011b1a32244742d0945
Autor:
Christine Lehmann
Publikováno v:
Pandaemonium Germanicum: Revista de Estudos Germanísticos, Vol 0, Iss 9, Pp 255-273 (2005)
No final dos anos 90, a ciência da literatura germanística discute sobre uma “nova literatura alemã pop”. O autor Christian Kracht é considerado o fundador dessa corrente literária. A presente contribuição ocupa-se com os romances de Krach
Externí odkaz:
https://doaj.org/article/9538afccd1d44027acf977affa6da6bb
Autor:
Christine Lehmann, Anna Heitmann, Satish Mishra, Paul-Christian Burda, Mirko Singer, Monica Prado, Livia Niklaus, Céline Lacroix, Robert Ménard, Friedrich Frischknecht, Rebecca Stanway, Photini Sinnis, Volker Heussler
Publikováno v:
PLoS Pathogens, Vol 10, Iss 8, p e1004336 (2014)
Plasmodium parasites express a potent inhibitor of cysteine proteases (ICP) throughout their life cycle. To analyze the role of ICP in different life cycle stages, we generated a stage-specific knockout of the Plasmodium berghei ICP (PbICP). Excision
Externí odkaz:
https://doaj.org/article/6aef6bf9991644ef8a83e2ca92eb41e0
Autor:
Stefanie Graewe, Kathleen E Rankin, Christine Lehmann, Christina Deschermeier, Leonie Hecht, Ulrike Froehlke, Rebecca R Stanway, Volker Heussler
Publikováno v:
PLoS Pathogens, Vol 7, Iss 9, p e1002224 (2011)
The protozoan parasite Plasmodium is transmitted by female Anopheles mosquitoes and undergoes obligatory development within a parasitophorous vacuole in hepatocytes before it is released into the bloodstream. The transition to the blood stage was pre
Externí odkaz:
https://doaj.org/article/d1555e3cf0184a8e818e7c6ccdc5996f
Autor:
Annika Rennenberg, Christine Lehmann, Anna Heitmann, Tina Witt, Guido Hansen, Krishna Nagarajan, Christina Deschermeier, Vito Turk, Rolf Hilgenfeld, Volker T Heussler
Publikováno v:
PLoS Pathogens, Vol 6, Iss 3, p e1000825 (2010)
Plasmodium parasites must control cysteine protease activity that is critical for hepatocyte invasion by sporozoites, liver stage development, host cell survival and merozoite liberation. Here we show that exoerythrocytic P. berghei parasites express
Externí odkaz:
https://doaj.org/article/4ea5549befea425aa2e2348298b2e841