Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Christine Lansche"'
Autor:
Akihisa Yamamoto, Julian Czajor, Michael Lanzer, Anil K. Dasanna, Motomu Tanaka, Benjamin Fröhlich, Alister Craig, Marek Cyrklaff, Cecilia P. Sanchez, Ulrich S. Schwarz, Christine Lansche
Publikováno v:
Biophysical Journal. 120:3315-3328
The pathology of Plasmodium falciparum malaria is largely defined by the cytoadhesion of infected erythrocytes to the microvascular endothelial lining. The complexity of the endothelial surface and the large range of interactions available for the in
Autor:
Arianna Mencattini, Christine Lansche, Irina Veith, Philippe Erbs, Jean-Marc Balloul, Eric Quemeneur, Stéphanie Descroix, Fatima Mechta-Grigoriou, Gérard Zalcman, Cécile Zaupa, Maria Carla Parrini, Eugenio Martinelli
Publikováno v:
Biosensorsbioelectronics. 215
Organ-on-chip and tumor-on-chip microfluidic cell cultures represent a fast-growing research field for modelling organ functions and diseases, for drug development, and for promising applications in personalized medicine. Still, one of the bottleneck
Autor:
Christine Lansche, Cecilia P. Sanchez, Benjamin Fröhlich, Peter Cloetens, Judith Thoma, Yang Yang, Julian Czajor, Michael Lanzer, Motomu Tanaka
Publikováno v:
Analytical Chemistry. 92:5765-5771
While there is ample evidence suggesting that carriers of heterozygous hemoglobin S and C are protected from life-threatening malaria, little is known about the underlying biochemical mechanisms at the single cell level. Using nanofocused scanning X-
Autor:
Cecilia P. Sanchez, Julia Jäger, Jacque Simpore, Christine Lansche, Serge Théophile Soubeiga, Hiroaki Ito, Bernd Buchholz, Motomu Tanaka, Benjamin Fröhlich, Ulrich S. Schwarz, Michael Lanzer, Marek Cyrklaff
Publikováno v:
Communications Biology, Vol 2, Iss 1, Pp 1-11 (2019)
Communications Biology
Communications Biology
During intraerythrocytic development, the human malaria parasite Plasmodium falciparum alters the mechanical deformability of its host cell. The underpinning biological processes involve gain in parasite mass, changes in the membrane protein composit
Autor:
Dimitris Missirlis, Christine Lansche, Marilou Tétard, Anil K. Dasanna, Benjamin Fröhlich, Benoit Gamain, Ulrich S. Schwarz, Cecilia P. Sanchez, Katharina A. Quadt, Bernd Buchholz, Motomu Tanaka, Michael Lanzer
Publikováno v:
Communications Biology, Vol 1, Iss 1, Pp 1-14 (2018)
Communications Biology
Communications Biology, Nature Publishing Group, 2018, 1 (1), ⟨10.1038/s42003-018-0223-3⟩
Communications Biology
Communications Biology, Nature Publishing Group, 2018, 1 (1), ⟨10.1038/s42003-018-0223-3⟩
Sickle cell trait, a common hereditary blood disorder, protects carriers from severe disease in infections with the human malaria parasite Plasmodium falciparum. Protection is associated with a reduced capacity of parasitized erythrocytes to cytoadhe
Autor:
Benjamin, Fröhlich, Yang, Yang, Judith, Thoma, Julian, Czajor, Christine, Lansche, Cecilia, Sanchez, Michael, Lanzer, Peter, Cloetens, Motomu, Tanaka
Publikováno v:
Analytical chemistry. 92(8)
While there is ample evidence suggesting that carriers of heterozygous hemoglobin S and C are protected from life-threatening malaria, little is known about the underlying biochemical mechanisms at the single cell level. Using nanofocused scanning X-
Publikováno v:
Biophysical journal. 112(9)
To avoid clearance by the spleen, red blood cells infected with the human malaria parasite Plasmodium falciparum (iRBCs) adhere to the vascular endothelium through adhesive protrusions called "knobs" that the parasite induces on the surface of the ho
Autor:
Anil K. Dasanna, Michael Lanzer, Ulrich S. Schwarz, Anna Battista, Friedrich Frischknecht, Christine Lansche
Publikováno v:
Biophysical Journal. 112:330a
During its journey through the human host, the malaria parasite makes strong use of adhesive interactions with its environment. We use biophysical assays and mathematical models to investigate the underlying mechanisms. After release into the host sk
Autor:
Sirikamol Srismith, Mailin Waldecker, Christine Lansche, Michael Lanzer, Marek Cyrklaff, Anil K. Dasanna, Ulrich S. Schwarz, Cecilia P. Sanchez, Marco Linke
Publikováno v:
Cellular Microbiology. 19:e12650
During intraerythrocytic development, Plasmodium falciparum increases the ion permeability of the erythrocyte plasma membrane to an extent that jeopardizes the osmotic stability of the host cell. A previously formulated numeric model has suggested th
Autor:
Ulrich Zachariae, Birgit Begemann, Christine Lansche, Petra Kilian, Christoph Fahlke, Bert L. de Groot, Ariane Leinenweber, David Ewers, Jan-Philipp Machtens, Rodolfo Briones
Publikováno v:
Biophysical Journal. 106:149a
Glutamatergic synaptic transmission critically depends on excitatory amino acid transporters (EAATs) that remove released neurotransmitters from the synaptic cleft and thereby ensure low extracellular glutamate concentrations in the central nervous s