Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Christine L. Wilcox"'
Publikováno v:
Journal of General Virology. 84:1071-1078
Herpes simplex virus type 1 (HSV-1) produces a life-long latent infection in neurons of the peripheral nervous system, primarily in the trigeminal and dorsal root ganglia. Neurons of these ganglia express high levels of the capsaicin receptor, also k
Autor:
Gary H. Cohen, Sarah M. Richart, Roselyn J. Eisenberg, Scott A. Simpson, Lewis I. Pizer, J. Charles Whitbeck, Claude Krummenacher, Christine L. Wilcox
Publikováno v:
Journal of Virology. 77:3307-3311
Primary cultures of rat and mouse sensory neurons were used to study the entry of herpes simplex virus type 1 (HSV-1). Soluble, truncated nectin-1 but not HveA prevented viral entry. Antibodies against nectin-1 also blocked infection of rat neurons.
Publikováno v:
Journal of Neurovirology. 9:390-398
Life-long latent herpes simplex virus type 1 (HSV-1) is harbored in sensory neurons where sporadic reactivation occurs. Reactivation stimuli may involve activation of apoptotic signaling in the neuron. Previous experiments have demonstrated that reac
Publikováno v:
Journal of Virology. 75:2912-2920
Herpes simplex virus type 1 (HSV-1) establishes a latent infection in neurons of the peripheral nervous system. During latent HSV-1 infection, viral gene expression is limited to latency-associated transcripts (LAT). HSV-1 remains latent until an unk
Autor:
Bruce W. Banfield, Bret N. Smith, Christine L. Wilcox, Gary E. Pickard, Lynn W. Enquist, F. Edward Dudek, Cynthia A. Smeraski
Publikováno v:
Proceedings of the National Academy of Sciences. 97:9264-9269
Physiological properties of central nervous system neurons infected with a pseudorabies virus were examined in vitro by using whole-cell patch-clamp techniques. A strain of pseudorabies virus (PRV 152) isogenic with the Bartha strain of PRV was const
Publikováno v:
The Journal of Neuroscience. 19:1965-1975
Precise growth cone guidance is the consequence of a continuous reorganization of actin filament structures within filopodia and lamellipodia in response to inhibitory and promoting cues. The small GTPases rac1, cdc42, and rhoA are critical for regul
Publikováno v:
Developmental Brain Research. 108:307-318
Regulation of expression of the voltage-gated chloride channel, ClC-2, was investigated during development and adult life in rat brain. RNase protection assays demonstrated a marked increase in levels of expression of ClC-2 in brain during early post
Autor:
Sharon E. Straus, Davol G. Tedder, Jose G. Assouline, Myron J. Levin, Christine L. Wilcox, Eli Somekh, Abbas Vafai
Publikováno v:
Pediatric Research. 32:699-703
A potential in vitro model of varicella-zoster virus (VZV) latency was developed. Dissociated human dorsal root ganglion cultures were infected with VZV and maintained for 1 wk in the presence of bromovinyl arabinosyl uracil, a potent inhibitor of VZ
Autor:
Myron J. Levin, Lewis I. Pizer, Elizabeth J. Hager, Curt R. Freed, Gary H. Cohen, Christine L. Wilcox, J. Charles Whitbeck, Claude Krummenacher, Roselyn J. Eisenberg, Michael D. Manchak, Scott A. Simpson
Publikováno v:
Journal of neurovirology. 11(2)
Immunocytochemistry detects nectin-1/HveC, nectin-2/HveB, and HVEM/HveA on the surface of sensory neurons and fibroblasts grown as primary cultures from human dorsal root ganglia. Viral entry into these cultured cells was assayed by infection with a
Autor:
Christine L. Wilcox, R. L. Smith
We have developed an in vitro model of herpes simplex virus (HSV) latency in primary neurons that mimics many aspects of HSV latency in animal models and the human disease (1-3). Using this model, we demonstrated that HSV-1 and HSV-2 establish latent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e4965e0d6172508d9049202605ee751
https://doi.org/10.1385/0-89603-347-3:317
https://doi.org/10.1385/0-89603-347-3:317