Výsledky vyhledávání - "Christine L. Martens"

A potent dimeric peptide antagonist of interleukin-5 that binds two interleukin-5 receptor α chains

Autor: Sue Bethell, Peter J. Schatz, Alexander Tsavaler, Chen Min-Jia, Yao-Fen Chen, Qun Yin, Erik A. Whitehorn, Christine L. Martens, England Bruce Padon, Ronald W. Barrett, Iain Uings, Palaniappan Balasubramanian, Murray McKinnon

Publikováno v: Proceedings of the National Academy of Sciences. 97:6862-6867

Two series of peptides that specifically bind to the extracellular domain of the alpha chain of the human interleukin-5 receptor (IL-5Ralpha), but share no primary sequence homology to IL-5, were identified from libraries of random recombinant peptid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd0c6a3f166025a247b018b85ab21232
https://doi.org/10.1073/pnas.110053997

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Peptides Which Bind to E-selectin and Block Neutrophil Adhesion

Autor: Christine L. Martens, Steven E. Cwirla, Rozanne Y.-W. Lee, Erik Whitehorn, Esther Y.-F. Chen, Alice Bakker, Edith L. Martin, Christopher Wagstrom, Priya Gopalan, C. Wayne Smith, Emily Tate, Kerry J. Koller, Peter J. Schatz, William J. Dower, Ronald W. Barrett

Publikováno v: Journal of Biological Chemistry. 270:21129-21136

E-selectin is an inducible cell adhesion molecule which mediates rolling of neutrophils on the endothelium, an early event in the development of an inflammatory response. Inhibition of selectin-mediated rolling is a possible means for controlling inf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f67661da5a560fdd16db5c3c91dde43
https://doi.org/10.1074/jbc.270.36.21129

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Human lymphocytes transcribe the cystic fibrosis transmembrane conductance regulator gene and exhibit CF-defective cAMP-regulated chloride current

Autor: Phyllis Gardner, Christine L. Martens, Paul T. Nghiem, Thomas V. Mcdonald

Publikováno v: Journal of Biological Chemistry. 267:3242-3248

Cystic fibrosis (CF) is the most common lethal genetic disease among Caucasians, primarily affecting epithelial tissues of the lung and gut. Mutations in a single gene, the cystic fibrosis transmembrane conductance regulator (CFTR), are responsible f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9cd9503112fa8bdfa35a0f32a2cb07a7
https://doi.org/10.1016/s0021-9258(19)50722-0

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Human cytomegalovirus late protein encoded by ie2: a trans-activator as well as a repressor of gene expression

Autor: Edward S. Mocarski, Christine L. Martens, Darlene E. Jenkins

Publikováno v: The Journal of general virology. 75

In order to study the function of human cytomegalovirus (HCMV) immediate early gene 2 (ie2) (UL122) gene products made at late times during infection, cDNA clones were isolated from an expression library made with 74 h post-infection mRNA. Based on s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22d77b8a3b073eb496c105c2e2eca4f6
https://pubmed.ncbi.nlm.nih.gov/8077932

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IgE-Binding Factors

Autor: Thomas F. Huff, Kevin W. Moore, Kimishige Ishizaka, Paula M. Jardieu, Christine L. Martens

Publikováno v: International Archives of Allergy and Immunology. 77:13-20

Gene cloning of rodent IgE-binding factors was accomplished, using messenger RN A of a rat T cell hybridoma, 23B6, which produce IgE-suppressive factor. Transfection of cos 7 monkey kidney cells with a eDNA clone resulted in the formation of rodent I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5a426ce39d521561303cc85077526e19
https://doi.org/10.1159/000233746

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cDNA clones encoding IgE-binding factors from a rat-mouse T-cell hybridoma

Autor: Mary L. Trounstine, Thomas F. Huff, Christine L. Martens, Paula M. Jardieu, Kimishige Ishizaka, Robert L. Coffman, Kevin W. Moore

Publikováno v: Proceedings of the National Academy of Sciences. 82:2460-2464

cDNA clones encoding rodent IgE-binding factors (IgE-BF) were isolated from cDNA libraries of a rat-mouse T hybridoma that secretes IgE-suppressive factor (IgE-SF) upon incubation with rat IgE. COS7 cells transfected with two of the cDNAs expressed I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fddd27e617f44e70b6a73838ace21bb
https://doi.org/10.1073/pnas.82.8.2460

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cDNA clones encoding murine IgE-binding factors represent multiple structural variants of intracisternal A-particle genes

Autor: Edward L. Kuff, Mary L. Trounstine, Judy A. Mietz, Christine L. Martens, Kevin W. Moore

Publikováno v: Proceedings of the National Academy of Sciences. 83:6583-6587

Previously [Moore, K. W., Jardieu, P., Mietz, J. A., Trounstine, M. L., Kuff, E. L., Ishizaka, K. & Martens, C. L. (1986) J. Immunol. 136, 4283-4290], we examined a T-hybridoma-derived cDNA clone, 8.3, that encodes a biologically active murine IgE-bi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3876b5fcf8ef44a7af51b51246ac7e4
https://doi.org/10.1073/pnas.83.17.6583

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Circadian rhythms of nucleic acid metabolism in Neurospora crassa

Autor: Christine L. Martens, Malcolm L. Sargent

Publikováno v: Journal of bacteriology. 117(3)

Wild-type, band, and fluffy strains of Neurospora crassa exhibit circadian rhythms of ribonucleic acid and deoxyribonucleic acid content in the growth-front hyphae of cultures grown on a solid medium. There is also a rhythm of 3 H-uridine incorporati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a3f4d9714abd0097b063649f9f5e1de
https://pubmed.ncbi.nlm.nih.gov/4273317

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