Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Christine Lämmer"'
Autor:
Andrea Schiefer, Marc P Hübner, Anna Krome, Christine Lämmer, Alexandra Ehrens, Tilman Aden, Marianne Koschel, Helene Neufeld, Lillibeth Chaverra-Muñoz, Rolf Jansen, Stefan Kehraus, Gabriele M König, Domen Pogorevc, Rolf Müller, Marc Stadler, Stephan Hüttel, Thomas Hesterkamp, Karl Wagner, Kenneth Pfarr, Achim Hoerauf
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 12, p e0008930 (2020)
Current efforts to eliminate the neglected tropical diseases onchocerciasis and lymphatic filariasis, caused by the filarial nematodes Onchocerca volvulus and Wuchereria bancrofti or Brugia spp., respectively, are hampered by lack of a short-course m
Externí odkaz:
https://doaj.org/article/d4370a71cad149209e66761eb918df85
Autor:
Stefan Schlabe, Patricia Korir, Christine Lämmer, Frederic Landmann, Bettina Dubben, Marianne Koschel, Anna Albers, Linda Batsa Debrah, Alexander Yaw Debrah, Marc P. Hübner, Kenneth Pfarr, Ute Klarmann-Schulz, Achim Hoerauf
Publikováno v:
Parasitology Research. 121:1199-1206
The filarial nematode Onchocerca volvulus causes onchocerciasis (river blindness), a neglected tropical disease affecting 21 million people, mostly in Sub-Saharan Africa. Targeting the endosymbiont Wolbachia with antibiotics leads to permanent steril
Autor:
Vera Serwaa Opoku, Alexander Yaw Debrah, Richard Phillips, Laura E. Layland, Manuel Ritter, Ute Klarmann-Schulz, Linda Batsa Debrah, Norman Nausch, Anna-Lena Sander, Marc Jacobsen, Christine Lämmer, Yusif Mubarik, Kenneth Pfarr, Achim Hoerauf, Wellington Owusu
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 101:84-92
Mansonella perstans infection, a vector-borne disease transmitted by female midges of the genus Culicoides, is an infection that, although not officially listed by the WHO, is nevertheless to be considered a neglected tropical disease. It affects mor
Corallopyronin A for short-course anti-wolbachial, macrofilaricidal treatment of filarial infections
Autor:
Stephan Hüttel, Marc Stadler, Marc P. Hübner, Stefan Kehraus, Rolf Jansen, Gabriele M. König, Tilman Aden, Alexandra Ehrens, Andrea Schiefer, Helene Neufeld, Achim Hoerauf, Anna K. Krome, Christine Lämmer, Lillibeth Chaverra-Muñoz, Thomas Hesterkamp, Marianne Koschel, Karl G. Wagner, Domen Pogorevc, Rolf Müller, Kenneth Pfarr
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 14, Iss 12, p e0008930 (2020)
e0008930
PLoS neglected tropical diseases
United States
PLoS Neglected Tropical Diseases, Vol 14, Iss 12, p e0008930 (2020)
e0008930
PLoS neglected tropical diseases
United States
Current efforts to eliminate the neglected tropical diseases onchocerciasis and lymphatic filariasis, caused by the filarial nematodes Onchocerca volvulus and Wuchereria bancrofti or Brugia spp., respectively, are hampered by lack of a short-course m
Autor:
Linda, Batsa Debrah, Richard O, Phillips, Kenneth, Pfarr, Ute, Klarmann-Schulz, Vera Serwaa, Opoku, Norman, Nausch, Wellington, Owusu, Yusif, Mubarik, Anna-Lena, Sander, Christine, Lämmer, Manuel, Ritter, Laura E, Layland, Marc, Jacobsen, Alexander Yaw, Debrah, Achim, Hoerauf
Publikováno v:
The American Journal of Tropical Medicine and Hygiene
Treating Mansonella perstans is challenged by the low efficacy of registered antihelminthics. Wolbachia endobacteria provide an alternative treatment target because depletion results in amicrofilaremia in filarial infections with Wuchereria bancrofti
Autor:
Sabine Specht, Heike Brötz-Oesterhelt, Helga Ruebsamen-Schaeff, Kenneth Pfarr, Christine Lämmer, Andrea Schiefer, Christian S. Lentz, Jennifer Vollmer, Achim Hoerauf
Publikováno v:
Journal of Antimicrobial Chemotherapy. 68:1790-1800
Background: Filarial infections causing lymphatic filariasis or onchocerciasis (river blindness) can be treated with antibiotics (e.g. doxycycline) targeting the essential endosymbiotic Wolbachia bacteria. The depletion of Wolbachia inhibits worm dev
Autor:
Gabriele M. König, Dmitry G. Vassylyev, Sabine Specht, Kelly L. Johnston, Alexander Schmitz, Andrea Schiefer, Christine Lämmer, Achim Hoerauf, Kenneth Pfarr, Till F. Schäberle
Publikováno v:
The Journal of infectious diseases. 206(2)
Doxycycline and rifampicin deplete essential Wolbachia from filarial nematodes that cause lymphatic filariasis or onchocerciasis, resulting in blocked worm development and death. However, doxycycline is contraindicated for children and pregnant/breas