Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Christine L, Powell"'
Autor:
Blair U. Bradford, Thomas M. O’Connell, Christopher Patrick Craig, Takeki Uehara, David W. Threadgill, Igor P. Pogribny, Ivan Rusyn, Lisa Bleyle, Christine L. Powell, Masato Tsuchiya, Dennis R. Koop, Stepan Melnyk
Publikováno v:
Toxicological Sciences. 115:131-139
Alcohol-induced liver injury (ALI) has been associated with, among other molecular changes, abnormal hepatic methionine metabolism, resulting in decreased levels of S-adenosylmethionine (SAM). Dietary methyl donor supplements such as SAM and betaine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cd4d77dae8796b151f512b940e54b33
https://doi.org/10.1093/toxsci/kfq031
https://doi.org/10.1093/toxsci/kfq031
Autor:
Christine L. Powell, Igor P. Pogribny, Volodymyr Tryndyak, Oleksandra Pavliv, Tetyana V. Bagnyukova
Publikováno v:
Brain Research. 1237:44-51
The age-associated decline in cellular antioxidant defenses and resultant accumulation of DNA damage in central nervous system has been mechanistically implicated in the etiology and pathogenesis of neurodegenerative diseases. Neurons possess a high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4529407f70a914904f53a42b9174c31
https://doi.org/10.1016/j.brainres.2008.07.073
https://doi.org/10.1016/j.brainres.2008.07.073
Publikováno v:
Harmful Algae. 7:45-51
Over the past decade diatom blooms of domoic acid (DA)-producing Pseudo-nitzschia spp. have been responsible for numerous marine mammal and bird mortalities in Monterey Bay, CA. One possible toxin vector is the market squid, Loligo opalescens , a sma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16929ca92b035956bea1c94601b6cc16
https://doi.org/10.1016/j.hal.2007.05.008
https://doi.org/10.1016/j.hal.2007.05.008
Autor:
Pamela K. Ross, Christine L. Powell, Robert Schoonhoven, Gary A. Boorman, Gunnar Boysen, Alexandra N. Heinloth, Richard S. Paules, Oksana Kosyk, Michael L. Cunningham, Ivan Rusyn, James A. Swenberg
Publikováno v:
Toxicological Sciences. 93:213-222
Toxicogenomics provides the ability to examine in greater detail the underlying molecular events that precede and accompany toxicity, thus allowing prediction of adverse events at much earlier times compared to classical toxicological end points. Ace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e5e9a6851dd7ac157f4da7d7b318368
https://doi.org/10.1093/toxsci/kfl030
https://doi.org/10.1093/toxsci/kfl030
Autor:
Dai Nakae, Fumiyuki Uematsu, Blair U. Bradford, Christine L. Powell, Oksana Kosyk, Edward K. Lobenhofer, Joel S. Parker, Ayumi Denda, Ivan Rusyn
Publikováno v:
Hepatology. 42:1137-1147
Hepatocellular carcinoma (HCC) is the terminal event in chronic liver diseases with repeated cycles of cellular injury and regeneration. Although much is known about the cellular pathogenesis and etiological agents leading to HCC, the molecular event
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49d5499fbea3eb8b35178ef25d0680f0
https://doi.org/10.1002/hep.20910
https://doi.org/10.1002/hep.20910
Autor:
Christine L. Powell, Donald M. Anderson, Bruce A. Keafer, Gregory J. Doucette, Jefferson T. Turner
Publikováno v:
Deep Sea Research Part II: Topical Studies in Oceanography. 52:2764-2783
The transfer of marine algal toxins involving a range of phytoplanktivorous vectors is well documented as a means of exposing organisms at higher trophic levels (including humans) to these naturally occurring yet harmful compounds. While previous stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0981de3e140ce68bcc5b4e94be4a8e0
https://doi.org/10.1016/j.dsr2.2005.06.031
https://doi.org/10.1016/j.dsr2.2005.06.031
Autor:
Shiyamalie R. Ruberu, Carolyn T. Wong, Gregory J. Doucette, S Kusum Perera, Christine L. Powell, Yun-Gang Liu, Gregg W. Langlois
Publikováno v:
Journal of AOAC INTERNATIONAL. 86:737-745
A receptor binding assay (RBA) for detection of paralytic shellfish poisoning (PSP) toxins was formatted for use in a high throughput detection system using microplate scintillation counting. The RBA technology was transferred from the National Ocean
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66e9c07e51ca5e0a3b7866a1198200bd
https://doi.org/10.1093/jaoac/86.4.737
https://doi.org/10.1093/jaoac/86.4.737
Autor:
Christine L. Powell, Gregory L. Boyer, Tracie R Baker, Gregory J. Doucette, F. Gerald Plumley
Publikováno v:
Toxicon. 41:339-347
Saxitoxins, the etiological agent of paralytic shellfish poisoning, are synthesized by dinoflagellates and cyanobacteria. Several reports indicate that bacteria are capable of saxitoxin synthesis. Two bacterial strains were isolated from saxitoxin-pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a620752f2c7909665f167fdf52c3cb10
https://doi.org/10.1016/s0041-0101(02)00314-8
https://doi.org/10.1016/s0041-0101(02)00314-8
Autor:
C.K Bretz, Gregory J. Doucette, Christine L. Powell, Kathi A. Lefebvre, M.E Ferdin, Susan L. Coale, Mary W. Silver, Rikk G. Kvitek
Publikováno v:
Toxicon. 40:1259-1265
Blooms of domoic acid (DA) synthesizing diatoms (Pseudo-nitzschia spp.) have been associated with the death and injury of hundreds of marine shorebirds and mammals, exposed humans to potentially serious health risks, and threatened to significantly i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f00fb6ce4cbb447c6d88a888f25c860b
https://doi.org/10.1016/s0041-0101(02)00129-0
https://doi.org/10.1016/s0041-0101(02)00129-0
Autor:
Craig A. Shoemaker, Jan H. Landsberg, Joyce J. Evans, Shahnaz Ibrahem, Mohammad A. Al-Sarawi, Muna Faraj, Patricia M. Glibert, Mohammad A Al-Jarallah, Allison Haywood, Phil Klesius, Christine L. Powell
Publikováno v:
Harmful Algae. 1:215-231
In August and September 2001, Kuwait Bay, a semi-enclosed embayment of the Arabian Gulf, experienced a massive fish kill involving over >2500 metric tons of wild mullet ( Liza klunzingeri ), due to the bacterium Streptococcus agalactiae . In the Bay,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d204c17330718de51983c1078b3e966c
https://doi.org/10.1016/s1568-9883(02)00013-6
https://doi.org/10.1016/s1568-9883(02)00013-6