Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Christine L, Gee"'
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0276413 (2023)
Genomic analysis of the unicellular choanoflagellate, Monosiga brevicollis (MB), revealed the remarkable presence of cell signaling and adhesion protein domains that are characteristically associated with metazoans. Strikingly, receptor tyrosine kina
Externí odkaz:
https://doaj.org/article/64fb4f0e5d15484eb78e2cd79d04d1b3
Publikováno v:
PLoS ONE, Vol 17, Iss 4 (2022)
Short segments of RNA displace one strand of a DNA duplex during diverse processes including transcription and CRISPR-mediated immunity and genome editing. These strand exchange events involve the intersection of two geometrically distinct helix type
Externí odkaz:
https://doaj.org/article/3625d2d6aa4b4144bf2a4395e0f828fb
Autor:
Stuart Mills, Jun Aishima, David Aragao, Tom Tudor Caradoc-Davies, Nathan Cowieson, Christine L. Gee, Daniel Ericsson, Stephen Harrop, Santosh Panjikar, Kate Mary Louise Smith, Alan Riboldi-Tunnicliffe, Rachel Williamson, Jason Roy Price
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 76, Iss 7, Pp 1136-1138 (2020)
Exceptionally large crystals of posnjakite, Cu4SO4(OH)6(H2O), formed during corrosion of a Swagelock(tm) Snubber copper gasket within the MX1 beamline at the ANSTO-Melbourne, Australian Synchrotron. The crystal structure was solved using synchrotron
Externí odkaz:
https://doaj.org/article/98564edfb3384f13a1180d2fc949e5bc
Autor:
Jason J. Paxman, Alvin W. Lo, Matthew J. Sullivan, Santosh Panjikar, Michael Kuiper, Andrew E. Whitten, Geqing Wang, Chi-Hao Luan, Danilo G. Moriel, Lendl Tan, Kate M. Peters, Minh-Duy Phan, Christine L. Gee, Glen C. Ulett, Mark A. Schembri, Begoña Heras
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Autotransporter proteins are localised to the bacterial surface and promote colonisation of host epithelial surfaces. Here, the authors present the crystal structure of autotransporter UpaB and show evidence for distinct binding sites for glycosamino
Externí odkaz:
https://doaj.org/article/84181b0a975c40f082db3fb0320d1436
Autor:
Jan Paulo T. Zaragoza, Adam R. Offenbacher, Shenshen Hu, Christine L. Gee, Zachary M. Firestein, Natalie Minnetian, Zhenyu Deng, Flora Fan, Anthony T. Iavarone, Judith P. Klinman
Publikováno v:
Proceedings of the National Academy of Sciences. 120
The enzyme soybean lipoxygenase (SLO) provides a prototype for deep tunneling mechanisms in hydrogen transfer catalysis. This work combines room temperature X-ray studies with extended hydrogen–deuterium exchange experiments to define a catalytical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ef794aaa19ad776552933cbe65f0165
https://doi.org/10.1073/pnas.2211630120
https://doi.org/10.1073/pnas.2211630120
Autor:
Neel H. Shah, Christine L. Gee, John Kuriyan, Jean M. Badroos, Helen T. Hobbs, Susan Marqusee
Publikováno v:
Protein Science : A Publication of the Protein Society
The catalytic activity of Syk‐family tyrosine kinases is regulated by a tandem Src homology 2 module (tSH2 module). In the autoinhibited state, this module adopts a conformation that stabilizes an inactive conformation of the kinase domain. The bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::838256900e2374647a4621bc4fc68d20
https://doi.org/10.1002/pro.4199
https://doi.org/10.1002/pro.4199
Autor:
Pradeep Bandaru, Neel H Shah, Moitrayee Bhattacharyya, John P Barton, Yasushi Kondo, Joshua C Cofsky, Christine L Gee, Arup K Chakraborty, Tanja Kortemme, Rama Ranganathan, John Kuriyan
Publikováno v:
eLife, Vol 6 (2017)
Ras proteins are highly conserved signaling molecules that exhibit regulated, nucleotide-dependent switching between active and inactive states. The high conservation of Ras requires mechanistic explanation, especially given the general mutational to
Externí odkaz:
https://doaj.org/article/34cff1c0dcd949968fc8a0b6544d4850
Genomic analysis of the unicellular choanoflagellate, Monosiga brevicollis (MB), revealed the remarkable presence of cell signaling and adhesion protein domains that are characteristically associated with metazoans. Strikingly, receptor tyrosine kina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e492a3ef20ca56687efd7f10b38bd685
https://doi.org/10.1101/2022.10.07.511304
https://doi.org/10.1101/2022.10.07.511304
Autor:
Moitrayee Bhattacharyya, Margaret M Stratton, Catherine C Going, Ethan D McSpadden, Yongjian Huang, Anna C Susa, Anna Elleman, Yumeng Melody Cao, Nishant Pappireddi, Pawel Burkhardt, Christine L Gee, Tiago Barros, Howard Schulman, Evan R Williams, John Kuriyan
Publikováno v:
eLife, Vol 5 (2016)
Activation triggers the exchange of subunits in Ca2+/calmodulin-dependent protein kinase II (CaMKII), an oligomeric enzyme that is critical for learning, memory, and cardiac function. The mechanism by which subunit exchange occurs remains elusive. We
Externí odkaz:
https://doaj.org/article/495a7e27d1bf4339b6867892a9602ba0
Autor:
Jan Paulo T. Zaragoza, Adam R. Offenbacher, Shenshen Hu, Christine L. Gee, Zachary M. Firestein, Natalie Minnetian, Zhenyu Deng, Flora Fan, Anthony T. Iavarone, Judith P. Klinman
The enzyme soybean lipoxygenase (SLO) provides a prototype for deep tunneling mechanisms in hydrogen transfer catalysis. This work combines room temperature X-ray studies with extended hydrogen deuterium exchange experiments to detect a radiating con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bac6f2887f20a341ea3b930c5657c441
https://doi.org/10.1101/2022.03.31.486235
https://doi.org/10.1101/2022.03.31.486235