Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Christine Kapaun"'
Autor:
Volker Heinemann, Andreas Jung, Thomas Kirchner, Jens Neumann, Markus Moehler, Thomas Decker, Swantje Held, Alexander Kiani, Martina Stauch, Andreas Schalhorn, Nicolas Moosmann, Ludwig Fischer von Weikersthal, Florian Kaiser, Boryana Ivanova, Christine Kapaun, Clemens Giessen-Jung, Ingrid Ricard, Dominik P. Modest, Sebastian Stintzing, Arndt Stahler
Outcome according to high vs. low unnormalized AREG expression in all patients and subgroups
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41829af0bb1ad893d90f8cb3597f0079
https://doi.org/10.1158/1078-0432.22476932
https://doi.org/10.1158/1078-0432.22476932
Autor:
Volker Heinemann, Andreas Jung, Thomas Kirchner, Jens Neumann, Markus Moehler, Thomas Decker, Swantje Held, Alexander Kiani, Martina Stauch, Andreas Schalhorn, Nicolas Moosmann, Ludwig Fischer von Weikersthal, Florian Kaiser, Boryana Ivanova, Christine Kapaun, Clemens Giessen-Jung, Ingrid Ricard, Dominik P. Modest, Sebastian Stintzing, Arndt Stahler
Purpose:Amphiregulin (AREG) and epiregulin (EREG) are ligands of EGFR. Predictive information for anti-EGFR treatment in metastatic colorectal cancer (mCRC) was observed, but data for other agents is limited.Experimental Design:Ligand mRNA expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52050a7f74cba65dfcd8f207d1d8d346
https://doi.org/10.1158/1078-0432.c.6529532.v1
https://doi.org/10.1158/1078-0432.c.6529532.v1
Autor:
Volker Heinemann, Andreas Jung, Thomas Kirchner, Jens Neumann, Markus Moehler, Thomas Decker, Swantje Held, Alexander Kiani, Martina Stauch, Andreas Schalhorn, Nicolas Moosmann, Ludwig Fischer von Weikersthal, Florian Kaiser, Boryana Ivanova, Christine Kapaun, Clemens Giessen-Jung, Ingrid Ricard, Dominik P. Modest, Sebastian Stintzing, Arndt Stahler
Univariate and multivariate Cox regression analyses for overall and progression-free survival in all patients.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29eeaf1c1ffd6093702b6991bb323397
https://doi.org/10.1158/1078-0432.22476935.v1
https://doi.org/10.1158/1078-0432.22476935.v1
Autor:
Volker Heinemann, Andreas Jung, Thomas Kirchner, Jens Neumann, Markus Moehler, Thomas Decker, Swantje Held, Alexander Kiani, Martina Stauch, Andreas Schalhorn, Nicolas Moosmann, Ludwig Fischer von Weikersthal, Florian Kaiser, Boryana Ivanova, Christine Kapaun, Clemens Giessen-Jung, Ingrid Ricard, Dominik P. Modest, Sebastian Stintzing, Arndt Stahler
Normalized AREG expression according to baseline characteristics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20a2910e5897433cb240746743a6d8e1
https://doi.org/10.1158/1078-0432.22476938
https://doi.org/10.1158/1078-0432.22476938
Autor:
Volker Heinemann, Andreas Jung, Thomas Kirchner, Jens Neumann, Markus Moehler, Thomas Decker, Swantje Held, Alexander Kiani, Martina Stauch, Andreas Schalhorn, Nicolas Moosmann, Ludwig Fischer von Weikersthal, Florian Kaiser, Boryana Ivanova, Christine Kapaun, Clemens Giessen-Jung, Ingrid Ricard, Dominik P. Modest, Sebastian Stintzing, Arndt Stahler
Data distribution of amphiregulin (AREG) and epiregulin (EREG) mRNA expression in the three randomized controlled trials FIRE-1, CIOX and FIRE-3. Logarithmic mRNA expression of AREG (A) was parametric distributed and could be normalized to a homogeno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::484f5aa5517b74c9e3e797170e5b4420
https://doi.org/10.1158/1078-0432.22476947
https://doi.org/10.1158/1078-0432.22476947
Autor:
Volker Heinemann, Andreas Jung, Thomas Kirchner, Jens Neumann, Markus Moehler, Thomas Decker, Swantje Held, Alexander Kiani, Martina Stauch, Andreas Schalhorn, Nicolas Moosmann, Ludwig Fischer von Weikersthal, Florian Kaiser, Boryana Ivanova, Christine Kapaun, Clemens Giessen-Jung, Ingrid Ricard, Dominik P. Modest, Sebastian Stintzing, Arndt Stahler
Median AREG (A) and EGFR (B) expression and their 95% confidence interval (95% CI, grey shaded). Median AREG expression was lower in right- compared to left-sided primary tumor locations, while only tumors located in caecum, ascending colon, hepatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::051f6dbe79719fd82f02896cdf4176de
https://doi.org/10.1158/1078-0432.22476944.v1
https://doi.org/10.1158/1078-0432.22476944.v1
Autor:
Volker Heinemann, Andreas Jung, Thomas Kirchner, Jens Neumann, Markus Moehler, Thomas Decker, Swantje Held, Alexander Kiani, Martina Stauch, Andreas Schalhorn, Nicolas Moosmann, Ludwig Fischer von Weikersthal, Florian Kaiser, Boryana Ivanova, Christine Kapaun, Clemens Giessen-Jung, Ingrid Ricard, Dominik P. Modest, Sebastian Stintzing, Arndt Stahler
Staining intensities of immunohistochemial EGFR expression, A: weak staining intensity (+1); B: moderate staining intensity (+2); C: strong staining intensity (+3). A score containing the percentage of stained cells (0 - 100 %) multiplied with staini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38bf11cc77acf7b92ddf91e2e3711e2a
https://doi.org/10.1158/1078-0432.22476950.v1
https://doi.org/10.1158/1078-0432.22476950.v1
Autor:
Volker Heinemann, Andreas Jung, Thomas Kirchner, Jens Neumann, Markus Moehler, Thomas Decker, Swantje Held, Alexander Kiani, Martina Stauch, Andreas Schalhorn, Nicolas Moosmann, Ludwig Fischer von Weikersthal, Florian Kaiser, Boryana Ivanova, Christine Kapaun, Clemens Giessen-Jung, Ingrid Ricard, Dominik P. Modest, Sebastian Stintzing, Arndt Stahler
Forest plot of individual trial analysis of high versus low amphiregulin (AREG) mRNA expression dichotomized by median and 3rd quartile showing (A) hazard ratios (HR) and 95% confidence interval (95% CI) for overall survival and (B) hazard ratios (HR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c98fb65c2d3910c8c90c66910d47394
https://doi.org/10.1158/1078-0432.22476941
https://doi.org/10.1158/1078-0432.22476941
Autor:
Volker Heinemann, Andreas Jung, Thomas Kirchner, Jens Neumann, Markus Moehler, Thomas Decker, Swantje Held, Alexander Kiani, Martina Stauch, Andreas Schalhorn, Nicolas Moosmann, Ludwig Fischer von Weikersthal, Florian Kaiser, Boryana Ivanova, Christine Kapaun, Clemens Giessen-Jung, Ingrid Ricard, Dominik P. Modest, Sebastian Stintzing, Arndt Stahler
Outcome of high vs. low normalized AREG expression according to molecular tumor characteristics by univariate Cox regression for overall and progression-free survival.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b61dd8d8480f64303ccc19867c2d3f7
https://doi.org/10.1158/1078-0432.22476929
https://doi.org/10.1158/1078-0432.22476929
Autor:
Arndt, Stahler, Sebastian, Stintzing, Dominik P, Modest, Ingrid, Ricard, Clemens, Giessen-Jung, Christine, Kapaun, Boryana, Ivanova, Florian, Kaiser, Ludwig, Fischer von Weikersthal, Nicolas, Moosmann, Andreas, Schalhorn, Martina, Stauch, Alexander, Kiani, Swantje, Held, Thomas, Decker, Markus, Moehler, Jens, Neumann, Thomas, Kirchner, Andreas, Jung, Volker, Heinemann
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 26(24)
Amphiregulin (Ligand mRNA expression;Of 688 patients with available material, highHigh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ec1397105f0260d0ebce252cc1332268
https://pubmed.ncbi.nlm.nih.gov/32943459
https://pubmed.ncbi.nlm.nih.gov/32943459
