Zobrazeno 1 - 10 of 27 pro vyhledávání: '"Christine K. Rudy"'
1
Cross-Presentation of Soluble and Cell-Associated Antigen by Murine Hepatocytes Is Enhanced by Collectrin Expression
Autor: Joseph S. Dolina, Christine K. Rudy, Young S. Hahn, William W. Tang, Sun-Sang J. Sung, Thu H. Le, Joey Lee, Sylvia Cechova
Publikováno v: The Journal of Immunology. 198:2341-2351
Cross-presentation is a modular series of intracellular events dictating the internalization and subsequent MHC class I (MHC I) display of extracellular Ags. This process has been defined in dendritic cells and plays a fundamental role in the inducti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efd802ca39efa5908751a6406575adc4
https://doi.org/10.4049/jimmunol.1502234
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2
Imaging flow cytometry elucidates limitations of microparticle analysis by conventional flow cytometry
Autor: Christine K. Rudy, Joanne Lannigan, Mark Yeager, Uta Erdbrügger, Kelly A. Dryden, Alexander L. Klibanov, Mark E. Etter
Publikováno v: Cytometry Part A. 85:756-770
Microparticles (MPs) are submicron vesicles released from cell membranes in response to activation, cell injury, or apoptosis. The clinical importance of MPs has become increasingly recognized, although no standardized method exists for their measure
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::78b854e5df1d12d393980754364df79f
https://doi.org/10.1002/cyto.a.22494
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4
Primary Human Hepatocytes in Spheroid Formation to Study Hepatitis C Infection1
Autor: Robert G. Sawyer, Tae W. Chong, Heather L. Evans, Jeremy R. Camden, Christine K. Rudy, Timothy L. Pruett, Michael G. Hughes, Robert L. Smith
Publikováno v: Journal of Surgical Research. 130:52-57
Background Hepatitis C (HCV) is a worldwide health problem, affecting nearly 170 million people. Current models for studying Hepatitis C have focused primarily on the use of poorly permissive cell lines and viral constructs, because of the lack of a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::446aa6524e48ef6a431521a8f7fdd492
https://doi.org/10.1016/j.jss.2005.04.043
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5
Impact of immunomodulatory oligodeoxynucleotides on cytokine production in the lipopolysaccharide-stimulated human whole blood model
Autor: Alison R. Saalwachter, Traci L. Hedrick, Shannon T. McElearney, Kangping Du, Robert G. Sawyer, Timothy L. Pruett, Daniel P. Raymond, Micheal G. Hughes, Heather L. Evans, Robert L. Smith, Christine K. Rudy, Tae W. Chong
Publikováno v: Surgery. 136:464-472
Background In studying potential immunotherapeutics for sepsis, we used a lipopolysaccharide (LPS)-stimulated whole blood model to test the immunomodulating capacity of cytosine-phospho-guanine oligodeoxynucleotides (CpG ODNs). We hypothesized that C
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba5f91b6242587e410c45ea861abe6f6
https://doi.org/10.1016/j.surg.2004.05.026
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6
E2 quasispecies specificity of hepatitis C virus association with allografts immediately after liver transplantation
Autor: Heather L. Evans, Robert G. Sawyer, Robert L. Smith, Timothy L. Pruett, Tae W. Chong, Julia C. Iezzoni, Christine K. Rudy, Michael G. Hughes
Publikováno v: Liver Transplantation. 10:208-216
It is unknown whether all hepatitis C virus (HCV) quasispecies variants found within patient serum have equal capacity to associate with the liver after transplantation; however, in vitro models of HCV infection suggest that variations in the hyperva
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::176afc1f6bdde16969400e3be5d80d87
https://doi.org/10.1002/lt.20060
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7
Preexposure of murine macrophages to CpG-containing oligonucleotides results in nuclear factor κB p50 homodimer-associated hyporesponsiveness
Autor: Shawn J. Pelletier, Long Jin, Robert G. Sawyer, Daniel P. Raymond, Traves D. Crabtree, Christine K. Rudy, Timothy L. Pruett
Publikováno v: Surgery. 132:245-251
Background. DNA containing the CpG motif is associated with immunomodulation of the innate immune response. Preexposure of macrophages to CpG DNA elicits a hyporesponsiveness to subsequent lipopolysaccharide (LPS) stimulation. We tested the hypothesi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9a2fe962bdeaf8fc05779eaf1e4a521
https://doi.org/10.1067/msy.2002.125355
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9
Excision of a conjugative transposon in vitro by the Int and Xis proteins of Tn916
Autor: Gordon Churchward, Kathryn L. Taylor, June R. Scott, Douglas Hinerfeld, Christine K. Rudy
Publikováno v: Nucleic Acids Research. 25:4061-4066
The roles of purified Int and Xis proteins of the conjugative transposon Tn 916 in excision of a deletion derivative of the closely related element Tn 1545 were investigated. At a low salt concentration (37.5 mM NaCl), Int alone was able to promote l
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbf6d211a1cffdd49a2222919ad2773f
https://doi.org/10.1093/nar/25.20.4061
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10
DNA binding by the Xis protein of the conjugative transposon Tn916
Autor: Gordon Churchward, June R. Scott, Christine K. Rudy
Publikováno v: Journal of Bacteriology. 179:2567-2572
We purified the Xis protein of the conjugative transposon Tn916 and showed by nuclease protection experiments that Xis bound specifically to sites close to each end of Tn916. These specific binding sites are close to, and in the same relative orienta
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::648e9f3173a9646f1c7085e0a842655c
https://doi.org/10.1128/jb.179.8.2567-2572.1997
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