Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Christine K. Hesje"'
Publikováno v:
American Journal of Veterinary Research. 76:860-868
OBJECTIVE To determine bactericidal effects of enrofloxacin, florfenicol, tilmicosin, and tulathromycin on clinical isolates of Mannheimia haemolytica at various bacterial densities and drug concentrations. SAMPLE 4 unique isolates of M haemolytica r
Publikováno v:
Clinical Ophthalmology (Auckland, N.Z.)
Wolfgang Haas, Christine M Sanfilippo, Christine K Hesje, Timothy W Morris Department of Microbiology and Sterilization Sciences, Bausch + Lomb, Inc, Rochester, NY, USA Introduction: Previous work has shown that besifloxacin, an 8-chloro-fluoroquinol
Publikováno v:
Current Eye Research. 36:1078-1085
Outbreaks of bacterial conjunctivitis have been linked to nontypeable strains of Streptococcus pneumoniae that lack a capsule, a key virulence factor for invasive infections. In contrast, isolates from sporadic, nonoutbreak cases of conjunctivitis we
Autor:
Wolfgang Haas, Christine M Sanfilippo, Timothy W. Morris, Chris M. Pillar, Christine K. Hesje
Publikováno v:
Journal of Antimicrobial Chemotherapy. 66:840-844
To compare the bactericidal activity of besifloxacin, moxifloxacin and gatifloxacin and determine the contribution of the preservative benzalkonium chloride (BAK) to bactericidal activity.Time-kill experiments were performed against four species (n=1
Publikováno v:
Chemotherapy. 57:363-371
Background: The impact of mutations in DNA gyrase and topoisomerase IV on minimum inhibitory concentrations (MICs) was investigated to better understand why besifloxacin has a higher potency against Staphylococcus aureus when compared to other fluoro
Publikováno v:
Current Eye Research
Purpose: Methicillin-resistant Staphylococcus aureus (MRSA) strains are commonly classified as hospital-acquired (HA) or community-acquired (CA). Typical HA-MRSA isolates are characterized by multidrug resistance and the SCCmec type II cassette, whil
Autor:
Chris M. Pillar, Christine K. Hesje, Wolfgang Haas, Timothy W. Morris, Christine M Sanfilippo
Publikováno v:
Journal of Antimicrobial Chemotherapy
Objectives Besifloxacin is a novel fluoroquinolone that was recently approved for topical treatment of bacterial conjunctivitis. The compound was shown to be active in vitro against a broad spectrum of bacteria, including isolates resistant to other
Publikováno v:
Expert Review of Respiratory Medicine. 1:7-16
Publikováno v:
The Journal of antimicrobial chemotherapy. 70(2)
BACKGROUND The mutant prevention concentration (MPC) reflects the antimicrobial susceptibility of the resistant mutant subpopulations present in large bacterial populations. In principle, combining the MPC with pharmacokinetic measurements can guide
Publikováno v:
International journal of antimicrobial agents. 45(6)
Streptococcus pneumoniae continues to be a significant respiratory pathogen, and increasing antimicrobial resistance compromises the use of β-lactam and macrolide antibiotics. Bacterial eradication impacts clinical outcome, and bacterial loads at th