Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Christine John"'
Autor:
Janina Jamasbi, RPh, Remco T.A. Megens, PhD, Mariaelvy Bianchini, MSc, Kerstin Uhland, PhD, Götz Münch, MD, Martin Ungerer, MD, Shachar Sherman, BSc, Alexander Faussner, PhD, Richard Brandl, MD, Christine John, MSc, Johannes Buchner, PhD, Christian Weber, MD, Reinhard Lorenz, MD, Natalie Elia, PhD, Wolfgang Siess, MD
Publikováno v:
JACC: Basic to Translational Science, Vol 1, Iss 3, Pp 131-142 (2016)
To enhance the antithrombotic properties of recombinant glycoprotein VI fragment crystallizable (GPVI-Fc), the authors incubated GPVI-Fc with anti-human Fc antibodies to cross-link the Fc tails of GPVI-Fc. Cross-linking potentiated the inhibition of
Externí odkaz:
https://doaj.org/article/61bf0fc198ea4ad180b532af81574356
Autor:
Jona T Stahmeyer, Siegbert Rossol, Florian Bert, Klaus H W Böker, Harald-Robert Bruch, Christoph Eisenbach, Ralph Link, Christine John, Stefan Mauss, Renate Heyne, Eckart Schott, Heike Pfeiffer-Vornkahl, Dietrich Hüppe, Christian Krauth
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159976 (2016)
Chronic hepatitis C virus infections (HCV) cause a significant public health burden. Introduction of telaprevir (TVR) and boceprevir (BOC) has increased sustained virologic response rates (SVR) in genotype 1 patients but were accompanied by higher tr
Externí odkaz:
https://doaj.org/article/86891e7aace0478981ef4dabc9c45612
Autor:
Steffen B Wiegand, Benjamin Heidrich, Simone Susser, Magdalena Rogalska-Taranta, Jörg Petersen, Klaus H W Böker, Natalia Grigorian, Ralph Link, Uwe Naumann, Christine John, Stefan Lueth, Peter Malfertheiner, Michael P Manns, Heiner Wedemeyer, Christoph Sarrazin, Markus Cornberg
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145622 (2015)
BACKGROUND:SNPs near the interferon lambda (IFNL) 3 gene are predictors for sustained virological response (SVR) in patients with chronic hepatitis C genotype (GT) 1. In addition, a dinucleotide frame shift in ss469415590 was described, which generat
Externí odkaz:
https://doaj.org/article/7667aca06f0b48d7959fd0f8abc267fa
Autor:
Christine John, Claus Niederau, Renate Heyne, Albrecht Stoehr, Hartwig Klinker, Gerlinde Teuber, Johannes Wiegand, U Naumann, Yvonne Serfert, Thomas Berg, Stefan Zeuzem, German Hepatitis C-Registry, K. Stein
Publikováno v:
European Journal of Gastroenterology & Hepatology. 34:76-83
Grazoprevir/elbasvir and glecaprevir/pibrentasvir (G/P) are the two preferred treatment options for patients with chronic hepatitis C virus (HCV) infection and a glomerular filtration rate (GFR)30 mL/min. Both therapies have been separately analyzed
Autor:
Hartwig Klinker, Karen Martin, Renate Heyne, Christine John, Markus Cornberg, Albrecht Stoehr, Holger Hinrichsen, Veronika Guenther, V Witte, Karl-Georg Simon, Stefan Zeuzem
Publikováno v:
European Journal of Gastroenterology & Hepatology
Background For treatment of genotype 1a (GT1a) infection with elbasvir/grazoprevir, the German guidelines recommend a differentiated approach depending on baseline viral load (BVL). For low BVL ≤800 000 IU/mL, treatment with 12 weeks elbasvir/grazo
Autor:
Christine John, Karl-Georg Simon, Stefan Mauss, Klaus H.W. Boeker, Heiner Wedemeyer, Rainer Günther, Christoph Sarrazin, Peter Buggisch, Claus Niederau, Johannes Vermehren, Annika Schmitt, Anita Pathil, Hartwig Klinker, Heribert Hillenbrand, Yvonne Serfert
Publikováno v:
Zeitschrift fur Gastroenterologie. 58(4)
Virologic failure to approved combinations of direct antiviral agents (DAA) in patients with chronic hepatitis C virus (HCV) infection is rare. Mostly it involves difficult to treat patients with advanced liver disease and prior interferon-experience
Autor:
K. Simon, Christine John, Thomas Berg, Manfred Bilzer, Hartwig Klinker, V Witte, K. Bayer, Albrecht Stoehr, M. Cornberg, B. Hintsche, Peter Buggisch, Uta Naumann, M Kuhn, Renate Heyne
Publikováno v:
Zeitschrift für Gastroenterologie. 56:E2-E89
Autor:
Safa Majeed, Christine Johnston, Saumeh Saeedi, Chloe Mighton, Vanessa Rokoszak, Ilham Abbasi, Sonya Grewal, Vernie Aguda, David Malkin, Yvonne Bombard
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 101438- (2024)
Externí odkaz:
https://doaj.org/article/10c847e6293b4b1480d7ead63d00546c
Autor:
Yashpal S. Chhonker, Wafaa N. Aldhafiri, Dhruvkumar Soni, Neerja Trivedi, Claire Steinbronn, Christine Johnson, Helen C. Stankiewicz Karita, Michael K. Paasche-Orlow, Ruanne Barnabas, Samuel L. Arnold, Daryl J. Murry
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) led to a global pandemic of coronavirus disease 2019 (COVID-19). Early in the pandemic, efforts were made to test the SARS-CoV-2 antiviral efficacy of repurposed medications that w
Externí odkaz:
https://doaj.org/article/d9282289d6214c0bb65f9b3353a11d61
Autor:
Kirsten E. Lyke, Robert L. Atmar, Clara Dominguez Islas, Christine M. Posavad, Meagan E. Deming, Angela R. Branche, Christine Johnston, Hana M. El Sahly, Srilatha Edupuganti, Mark J. Mulligan, Lisa A. Jackson, Richard E. Rupp, Christina A. Rostad, Rhea N. Coler, Martín Bäcker, Angelica C. Kottkamp, Tara M. Babu, David Dobrzynski, Judith M. Martin, Rebecca C. Brady, Robert W. Frenck, Kumaravel Rajakumar, Karen Kotloff, Nadine Rouphael, Daniel Szydlo, Rahul PaulChoudhury, Janet I. Archer, Sonja Crandon, Brian Ingersoll, Amanda Eaton, Elizabeth R. Brown, M. Juliana McElrath, Kathleen M. Neuzil, David S. Stephens, Diane J. Post, Bob C. Lin, Leonid Serebryannyy, John H. Beigel, David C. Montefiori, Paul C. Roberts, the DMID 21-0012 Study Group
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-10 (2023)
Abstract As part of a multicenter study evaluating homologous and heterologous COVID-19 booster vaccines, we assessed the magnitude, breadth, and short-term durability of binding and pseudovirus-neutralizing antibody (PsVNA) responses following a sin
Externí odkaz:
https://doaj.org/article/25f04fdb644f4573b07bd819954db49f