Výsledky vyhledávání - "Christine J Hastey"

Akademický článek

Suppression of Long-Lived Humoral Immunity Following Borrelia burgdorferi Infection.

Autor: Rebecca A Elsner, Christine J Hastey, Kimberly J Olsen, Nicole Baumgarth

Publikováno v: PLoS Pathogens, Vol 11, Iss 7, p e1004976 (2015)

Lyme Disease caused by infection with Borrelia burgdorferi is an emerging infectious disease and already by far the most common vector-borne disease in the U.S. Similar to many other infections, infection with B. burgdorferi results in strong antibod

Externí odkaz: https://doaj.org/article/293217c6fe9046ff958d31c9d148803e

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Akademický článek

Coccidioides Endospores and Spherules Draw Strong Chemotactic, Adhesive, and Phagocytic Responses by Individual Human Neutrophils.

Autor: Cheng-Yuk Lee, George R Thompson, Christine J Hastey, Gregory C Hodge, Jennine M Lunetta, Demosthenes Pappagianis, Volkmar Heinrich

Publikováno v: PLoS ONE, Vol 10, Iss 6, p e0129522 (2015)

Coccidioides spp. are dimorphic pathogenic fungi whose parasitic forms cause coccidioidomycosis (Valley fever) in mammalian hosts. We use an innovative interdisciplinary approach to analyze one-on-one encounters between human neutrophils and two form

Externí odkaz: https://doaj.org/article/0980decc58df46468cba361305a09491

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Akademický článek

The Vi capsular polysaccharide enables Salmonella enterica serovar typhi to evade microbe-guided neutrophil chemotaxis.

Autor: Tamding Wangdi, Cheng-Yuk Lee, Alanna M Spees, Chenzhou Yu, Dawn D Kingsbury, Sebastian E Winter, Christine J Hastey, R Paul Wilson, Volkmar Heinrich, Andreas J Bäumler

Publikováno v: PLoS Pathogens, Vol 10, Iss 8, p e1004306 (2014)

Salmonella enterica serovar Typhi (S. Typhi) causes typhoid fever, a disseminated infection, while the closely related pathogen S. enterica serovar Typhimurium (S. Typhimurium) is associated with a localized gastroenteritis in humans. Here we investi

Externí odkaz: https://doaj.org/article/06b68d1c8b264bff822402c9794186db

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Akademický článek

Lymphoadenopathy during lyme borreliosis is caused by spirochete migration-induced specific B cell activation.

Autor: Stefan S Tunev, Christine J Hastey, Emir Hodzic, Sunlian Feng, Stephen W Barthold, Nicole Baumgarth

Publikováno v: PLoS Pathogens, Vol 7, Iss 5, p e1002066 (2011)

Lymphadenopathy is a hallmark of acute infection with Borrelia burgdorferi, a tick-borne spirochete and causative agent of Lyme borreliosis, but the underlying causes and the functional consequences of this lymph node enlargement have not been reveal

Externí odkaz: https://doaj.org/article/e9e1a34ba75d4787a2d6a68d0db820d7

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CD4 + T Cells Promote Antibody Production but Not Sustained Affinity Maturation during Borrelia burgdorferi Infection

Autor: Rebecca A. Elsner, Christine J. Hastey, Nicole Baumgarth

Publikováno v: Infection and immunity, vol 83, iss 1

CD4 T cells are crucial for enhancing B cell-mediated immunity, supporting the induction of high-affinity, class-switched antibody responses, long-lived plasma cells, and memory B cells. Previous studies showed that the immune response to Borrelia bu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33742c267e66c1f2a39b521228507337
https://doi.org/10.1128/iai.02471-14

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Suppression of Long-Lived Humoral Immunity Following Borrelia burgdorferi Infection

Autor: Nicole Baumgarth, Christine J. Hastey, Kimberly J. Olsen, Rebecca A. Elsner

Publikováno v: PLoS pathogens, vol 11, iss 7
PLoS Pathogens, Vol 11, Iss 7, p e1004976 (2015)
PLoS Pathogens

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1b2c97f144cb555aa6b24c5e771df05
https://escholarship.org/uc/item/2g04j6tg

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Infection-induced type I interferons activate CD11b on B-1 cells for subsequent lymph node accumulation

Autor: Ulrich Kalinke, Neha Dixit, Youn Soo Choi, Elizabeth E. Waffarn, Christine J. Hastey, Nicole Baumgarth, Simon R. Cherry, Scott I. Simon

Publikováno v: Nature communications, vol 6, iss 1

Innate-like B-1a lymphocytes rapidly redistribute to regional mediastinal lymph nodes (MedLNs) during influenza infection to generate protective IgM. Here we demonstrate that influenza infection-induced type I interferons directly stimulate body cavi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9157327f69ea732a2d296cf3a615a7fc
https://hdl.handle.net/10033/615621

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MyD88- and TRIF-independent induction of type I interferon drives naive B cell accumulation but not loss of lymph node architecture in Lyme disease

Autor: Christine J. Hastey, Jennine Ochoa, Nicole Baumgarth, Kimberley J. Olsen, Stephen W. Barthold

Publikováno v: Infection and immunity, vol 82, iss 4

Rapidly after infection, live Borrelia burgdorferi , the causative agent of Lyme disease, is found within lymph nodes, causing rapid and strong tissue enlargement, a loss of demarcation between B cell follicles and T cell zones, and an unusually larg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10af785e9fd23a4ea7a88efa6d4cad82
https://escholarship.org/uc/item/9mc7n60x

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The Vi capsular polysaccharide enables Salmonella enterica serovar typhi to evade microbe-guided neutrophil chemotaxis

Autor: Andreas J. Bäumler, Dawn D. Kingsbury, Volkmar Heinrich, Sebastian E. Winter, Chenzhou Yu, Christine J. Hastey, Alanna M. Spees, Cheng Yuk Lee, R. Paul Wilson, Tamding Wangdi

Publikováno v: PLoS Pathogens, Vol 10, Iss 8, p e1004306 (2014)
PLoS pathogens, vol 10, iss 8
PLoS Pathogens
Wangdi, T; Lee, CY; Spees, AM; Yu, C; Kingsbury, DD; Winter, SE; et al.(2014). The Vi Capsular Polysaccharide Enables Salmonella enterica Serovar Typhi to Evade Microbe-Guided Neutrophil Chemotaxis. PLoS Pathogens, 10(8). doi: 10.1371/journal.ppat.1004306. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/3bt8g2q0

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63d5990c43e68f4f756966f8dca5f107
https://pubmed.ncbi.nlm.nih.gov/25157696

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Delays and diversions mark the development of B cell responses to Borrelia burgdorferi infection

Autor: Nicole Baumgarth, Stephen W. Barthold, Christine J. Hastey, Rebecca A. Elsner

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 188(11)

B cell responses modulate disease during infection with Borrelia burgdorferi, the causative agent of Lyme disease, but are unable to clear the infection. Previous studies have demonstrated that B. burgdorferi infection induces predominantly T-indepen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1d1f22e5ad71ba0f48c6f303066e9ed
https://pubmed.ncbi.nlm.nih.gov/22547698

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