Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Christine J Fontaine"'
Publikováno v:
Frontiers in Pediatrics, Vol 2 (2014)
Prenatal ethanol exposure (PNEE) has been linked to widespread impairments in brain structure and function. There are a number of animal models that are used to study the structural and functional deficits caused by prenatal ethanol exposure, includi
Externí odkaz:
https://doaj.org/article/104261162888416491368aa2420d0fda
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 1192 (2022)
Alcohol use disorder (AUD) encompasses the dysregulation of multiple brain circuits involved in executive function leading to excessive consumption of alcohol, despite negative health and social consequences and feelings of withdrawal when access to
Externí odkaz:
https://doaj.org/article/c9500d3725274bbcbee466212f7ccdfa
Publikováno v:
J Neurophysiol
Choline is an essential nutrient under evaluation as a cognitive enhancing treatment for fetal alcohol spectrum disorders (FASD) in clinical trials. As a result, there is increased pressure to identify therapeutic mechanism(s) of action. Choline is n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f96f0abf840aee26489ba9fc3c21b35b
https://doi.org/10.1152/jn.00136.2021
https://doi.org/10.1152/jn.00136.2021
Autor:
Pedro Grandes, Erin L. Gräfe, Christine J. Fontaine, Itziar Bonilla-Del Río, Brian R. Christie, Cristina Pinar
Publikováno v:
Learn Mem
Cannabinoid receptors are widely expressed throughout the hippocampal formation, but are particularly dense in the dentate gyrus (DG) subregion. We, and others, have shown in mice that cannabinoid type 1 receptors (CB1Rs) are involved in a long-term
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::607d6bfdefd78586d28ad58de3282df8
https://doi.org/10.1101/lm.050666.119
https://doi.org/10.1101/lm.050666.119
Autor:
María González-Perez, Monica Tyagi, Melissa E. Freeman, Manjinder S. Cheema, Taylor L. Gretzinger, Brian R. Christie, Christine J. Fontaine, Juan Ausió
Publikováno v:
Biochemistry and Cell Biology. 97:431-436
Fetal alcohol spectrum disorder (FASD) is caused by prenatal exposure to ethanol and has been linked to neurodevelopmental impairments. Alcohol has the potential to alter some of the epigenetic components that play a critical role during development.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d47c9810528f518466fd06300a901d67
https://doi.org/10.1139/bcb-2018-0240
https://doi.org/10.1139/bcb-2018-0240
Autor:
Christine J. Fontaine, Leire Lekunberri, Maria Elvira Giordano, Sara Peñasco, Ianire Buceta, Pedro Grandes, Leire Reguero, Irantzu Rico-Barrio, Nagore Puente, Almudena Ramos, Fernando Rodríguez de Fonseca, Itziar Terradillos, Juan Mendizabal-Zubiaga, Inmaculada Gerrikagoitia, Izaskun Elezgarai
Publikováno v:
Addiction Biology. 24:969-980
Binge drinking (BD) is a common pattern of ethanol (EtOH) consumption by adolescents. The brain effects of the acute EtOH exposure are well-studied; however, the long-lasting cognitive and neurobehavioral consequences of BD during adolescence are onl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddfc25e8ad9d8fed46b8d9d85957d4b2
https://doi.org/10.1111/adb.12667
https://doi.org/10.1111/adb.12667
Autor:
Irantzu Rico-Barrio, Joan Sallés, Nagore Puente, Fernando Rodríguez de Fonseca, Almudena Ramos, Leire Reguero, Gontzal García del Caño, Christine J. Fontaine, Juan Suárez, Xabier Aretxabala, Sergio Barrondo, Brian R. Christie, Patrick C. Nahirney, Pedro Grandes, Sara Peñasco, Inmaculada Gerrikagoitia, Izaskun Elezgarai
Publikováno v:
Neuropsychopharmacology
Binge drinking is a significant problem in adolescent populations, and because of the reciprocal interactions between ethanol (EtOH) consumption and the endocannabinoid (eCB) system, we sought to determine if adolescent EtOH intake altered the locali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef9fb1eff0d5116c3f02432a201c8518
https://www.nature.com/articles/s41386-019-0530-5.pdf
https://www.nature.com/articles/s41386-019-0530-5.pdf
Impaired Bidirectional Synaptic Plasticity in Juvenile Offspring Following Prenatal Ethanol Exposure
Autor:
Konrad E. Suesser, Waisley Yang, Cristina Pinar, Brian R. Christie, Angela F. Pang, James Sung Jun Choi, Christine J. Fontaine
Publikováno v:
Alcohol Clin Exp Res
BACKGROUND: The hippocampus is particularly vulnerable to the teratogenic effects of prenatal ethanol exposure (PNEE), and hippocampal structural and functional deficits are thought to contribute to the learning and memory deficits that are a hallmar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8edc4a9b1854448fcb7f2b33cb49ab0d
https://pubmed.ncbi.nlm.nih.gov/31386206
https://pubmed.ncbi.nlm.nih.gov/31386206
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1802485b161935f572cd5431d2843a5e
https://doi.org/10.1096/fasebj.2019.33.1_supplement.448.5
https://doi.org/10.1096/fasebj.2019.33.1_supplement.448.5
Autor:
Cristina Pinar, Carina P. Lottenberg, Suk Yu Yau, Alicia Meconi, Christine J. Fontaine, Arian Shamei, Brian R. Christie, Zoe Sharp
Publikováno v:
Brain Plasticity
Fragile X syndrome (FXS) is the most common cause of inherited intellectual disability that can be traced to a single gene mutation. This disorder is caused by the hypermethylation of the Fmr1 gene, which impairs translation of Fragile X Mental Retar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e14fa70c8a18f108608a2e51dab4e4a8
https://pubmed.ncbi.nlm.nih.gov/30598869
https://pubmed.ncbi.nlm.nih.gov/30598869