Zobrazeno 1 - 10
of 408
pro vyhledávání: '"Christine J, Harrison"'
Autor:
Mireia Ramos‐Muntada, Juan L. Trincado, Joan Blanco, Clara Bueno, Virginia C. Rodríguez‐Cortez, Alex Bataller, Belén López‐Millán, Claire Schwab, Margarita Ortega, Pablo Velasco, Maria L. Blanco, Josep Nomdedeu, Manuel Ramírez‐Orellana, Alfredo Minguela, Jose L. Fuster, Esther Cuatrecasas, Mireia Camós, Paola Ballerini, Gabriele Escherich, Judith Boer, Monique DenBoer, Jesús M. Hernández‐Rivas, Maria J. Calasanz, Giovanni Cazzaniga, Christine J. Harrison, Pablo Menéndez, Oscar Molina
Publikováno v:
Molecular Oncology, Vol 16, Iss 16, Pp 2899-2919 (2022)
B‐cell acute lymphoblastic leukemia (B‐ALL) is the commonest childhood cancer. High hyperdiploidy (HHD) identifies the most frequent cytogenetic subgroup in childhood B‐ALL. Although hyperdiploidy represents an important prognostic factor in ch
Externí odkaz:
https://doaj.org/article/c4efc3858e8a4dd59893e2d44eb72c0d
Autor:
Simon Bomken, Amir Enshaei, Edward C. Schwalbe, Aneta Mikulasova, Yunfeng Dai, Masood Zaka, Kent T.M. Fung, Matthew Bashton, Huezin Lim, Lisa Jones, Nefeli Karataraki, Emily Winterman, Cody Ashby, Andishe Attarbaschi, Yves Bertrand, Jutta Bradtke, Barbara Buldini, G.A. Amos Burke, Giovanni Cazzaniga, Gudrun Gohring, Hesta A. de Groot-Kruseman, Claudia Haferlach, Luca Lo Nigro, Mayur Parihar, Adriana Plesa, Emma Seaford, Edwin Sonneveld, Sabine Strehl, Vincent H.J. van der Velden, Vikki Rand, Stephen P. Hunger, Christine J. Harrison, Chris M. Bacon, Frederik W. van Delft, Mignon L. Loh, John Moppett, Josef Vormoor, Brian A. Walker, Anthony V. Moorman, Lisa J. Russell
Publikováno v:
Haematologica, Vol 108, Iss 3 (2022)
Rarely, immunophenotypically immature B-cell precursor acute lymphoblastic leukemia (BCP-ALL) carries an immunoglobulin- MYC rearrangement (IG-MYC-r). This can result in diagnostic confusion with Burkitt lymphoma/leukemia and use of individualized tr
Externí odkaz:
https://doaj.org/article/7ac03037b4cc476bb5a3d391aea80fe8
Autor:
Leonardo Gomes de Lima, Edmund Howe, Vijay Pratap Singh, Tamara Potapova, Hua Li, Baoshan Xu, Jemma Castle, Steve Crozier, Christine J. Harrison, Steve C. Clifford, Karen H. Miga, Sarra L. Ryan, Jennifer L. Gerton
Publikováno v:
Cell Genomics, Vol 1, Iss 3, Pp 100064- (2021)
Summary: Centromeric α-satellite repeats represent ∼6% of the human genome, but their length and repetitive nature make sequencing and analysis of those regions challenging. However, centromeres are essential for the stable propagation of chromoso
Externí odkaz:
https://doaj.org/article/d9a43af8e46246b39eeb471796f82966
Autor:
Thomas Creasey, Emilio Barretta, Sarra L. Ryan, Ellie Butler, Amy A. Kirkwood, Daniel Leongamornlert, Elli Papaemmanuil, Pip Patrick, Laura Clifton-Hadley, Bela Patel, Tobias Menne, Andrew K. McMillan, Christine J. Harrison, Clare J. Rowntree, Nick Morley, David I. Marks, Adele K. Fielding, Anthony V. Moorman
Publikováno v:
Haematologica, Vol 107, Iss 9 (2021)
Despite being predominantly a childhood disease, the incidence of acute lymphoblastic leukemia (ALL) has a second peak in adults aged 60 years and over. These older adults fare extremely poorly with existing treatment strategies and very few studies
Externí odkaz:
https://doaj.org/article/8a04be27587840df8c9f2b5d4ebd7f27
Autor:
Romy E. van Weelderen, Kim Klein, Christine J. Harrison, Yilin Jiang, Jonas Abrahamsson, Nira Arad-Cohen, Emmanuelle Bart-Delabesse, Barbara Buldini, Barbara De Moerloose, Michael N. Dworzak, Sarah Elitzur, José M. Fernández Navarro, Robert B. Gerbing, Bianca F. Goemans, Hester A. de Groot-Kruseman, Erin Guest, Shau-Yin Ha, Henrik Hasle, Charikleia Kelaidi, Hélène Lapillonne, Guy Leverger, Franco Locatelli, Riccardo Masetti, Takako Miyamura, Ulrika Norén-Nyström, Sophia Polychronopoulou, Mareike Rasche, Jeffrey E. Rubnitz, Jan Stary, Anne Tierens, Daisuke Tomizawa, C. Michel Zwaan, Gertjan J.L. Kaspers
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 41(16), 2963-2974. American Society of Clinical Oncology
van Weelderen, R E, Klein, K, Harrison, C J, Jiang, Y, Abrahamsson, J, Arad-Cohen, N, Bart-Delabesse, E, Buldini, B, de Moerloose, B, Dworzak, M N, Elitzur, S, Fernández Navarro, J M, Gerbing, R B, Goemans, B F, de Groot-Kruseman, H A, Guest, E, Ha, S-Y, Hasle, H, Kelaidi, C, Lapillonne, H L, Leverger, G, Locatelli, F, Masetti, R, Miyamura, T, Norén-Nyström, U, Polychronopoulou, S, Rasche, M, Rubnitz, J E, Stary, J, Tierens, A, Tomizawa, D, Zwaan, C M & Kaspers, G J L 2023, ' Measurable Residual Disease and Fusion Partner Independently Predict Survival and Relapse Risk in Childhood KMT2A-Rearranged Acute Myeloid Leukemia : A Study by the International Berlin-Frankfurt-Münster Study Group ', Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol. 41, no. 16, pp. 2963-2974 . https://doi.org/10.1200/JCO.22.02120
JOURNAL OF CLINICAL ONCOLOGY
van Weelderen, R E, Klein, K, Harrison, C J, Jiang, Y, Abrahamsson, J, Arad-Cohen, N, Bart-Delabesse, E, Buldini, B, de Moerloose, B, Dworzak, M N, Elitzur, S, Fernández Navarro, J M, Gerbing, R B, Goemans, B F, de Groot-Kruseman, H A, Guest, E, Ha, S-Y, Hasle, H, Kelaidi, C, Lapillonne, H L, Leverger, G, Locatelli, F, Masetti, R, Miyamura, T, Norén-Nyström, U, Polychronopoulou, S, Rasche, M, Rubnitz, J E, Stary, J, Tierens, A, Tomizawa, D, Zwaan, C M & Kaspers, G J L 2023, ' Measurable Residual Disease and Fusion Partner Independently Predict Survival and Relapse Risk in Childhood KMT2A-Rearranged Acute Myeloid Leukemia : A Study by the International Berlin-Frankfurt-Münster Study Group ', Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol. 41, no. 16, pp. 2963-2974 . https://doi.org/10.1200/JCO.22.02120
JOURNAL OF CLINICAL ONCOLOGY
PURPOSE A previous study by the International Berlin-Frankfurt-Münster Study Group (I-BFM-SG) on childhood KMT2A-rearranged ( KMT2A-r) AML demonstrated the prognostic value of the fusion partner. This I-BFM-SG study investigated the value of flow cy
Autor:
Bruno A. Lopes, Claus Meyer, Thayana C. Barbosa, Caroline P. Poubel, Marcela B. Mansur, Nicolas Duployez, Matthew Bashton, Christine J. Harrison, Udo zur Stadt, Martin Horstmann, Maria S. Pombo-de-Oliveira, Chiara Palmi, Gianni Cazzaniga, Nicola C. Venn, Rosemary Sutton, Cristina N. Alonso, Grigory Tsaur, Sanjeev K. Gupta, Sameer Bakhshi, Rolf Marschalek, Mariana Emerenciano
Publikováno v:
Translational Oncology, Vol 12, Iss 5, Pp 726-732 (2019)
IKZF1 deletion (ΔIKZF1) is an important predictor of relapse in both childhood and adult B-cell precursor acute lymphoblastic leukemia (B-ALL). Previously, we revealed that COBL is a hotspot for breakpoints in leukemia and could promote IKZF1 deleti
Externí odkaz:
https://doaj.org/article/f6be09f1858441f3b7c04f22559dd5bf
Autor:
Simon Bomken, Amir Enshaei, Edward C. Schwalbe, Aneta Mikulasova, Yunfeng Dai, Masood Zaka, Kent T.M. Fung, Matthew Bashton, Huezin Lim, Lisa Jones, Nefeli Karataraki, Emily Winterman, Cody Ashby, Andishe Attarbaschi, Yves Bertrand, Jutta Bradtke, Barbara Buldini, G.A. Amos Burke, Giovanni Cazzaniga, Gudrun Gohring, Hesta A. De Groot-Kruseman, Claudia Haferlach, Luca Lo Nigro, Mayur Parihar, Adriana Plesa, Emma Seaford, Edwin Sonneveld, Sabine Strehl, Vincent H.J. Van der Velden, Vikki Rand, Stephen P. Hunger, Christine J. Harrison, Chris M. Bacon, Frederik W. Van Delft, Mignon L. Loh, John Moppett, Josef Vormoor, Brian A. Walker, Anthony V. Moorman, Lisa J. Russell
Publikováno v:
Haematologica, 108(3), 717-731. Ferrata Storti Foundation
Rarely, immunophenotypically immature B-cell precursor acute lymphoblastic leukemia (BCP-ALL) carries an immunoglobulin- MYC rearrangement (IG-MYC-r). This can result in diagnostic confusion with Burkitt lymphoma/leukemia and use of individualized tr
Autor:
Paul B. Sinclair, Ruth E. Cranston, Prahlad Raninga, Joanna Cheng, Rebecca Hanna, Zoe Hawking, Steven Hair, Sarra L. Ryan, Amir Enshaei, Sirintra Nakjang, Vikki Rand, Helen J. Blair, Anthony V. Moorman, Olaf Heidenreich, Christine J. Harrison
Publikováno v:
Leukemia. 37:636-649
A common problem in the study of human malignancy is the elucidation of cancer driver mechanisms associated with recurrent deletion of regions containing multiple genes. Taking B-cell acute lymphoblastic leukaemia (B-ALL) and large deletions of 6q [d
Autor:
Sarra L. Ryan, John F. Peden, Zoya Kingsbury, Claire J. Schwab, Terena James, Petri Polonen, Martina Mijuskovic, Jenn Becq, Richard Yim, Ruth E. Cranston, Dale J. Hedges, Kathryn G. Roberts, Charles G. Mullighan, Ajay Vora, Lisa J. Russell, Robert Bain, Anthony V. Moorman, David R. Bentley, Christine J. Harrison, Mark T. Ross
Publikováno v:
Leukemia. 37:518-528
Childhood B-cell acute lymphoblastic leukaemia (B-ALL) is characterised by recurrent genetic abnormalities that drive risk-directed treatment strategies. Using current techniques, accurate detection of such aberrations can be challenging, due to the
Autor:
Claire Schwab, Ruth E. Cranston, Sarra L. Ryan, Ellie Butler, Emily Winterman, Zoe Hawking, Matthew Bashton, Amir Enshaei, Lisa J. Russell, Zoya Kingsbury, John F. Peden, Emilio Barretta, James Murray, Jude Gibson, Andrew C. Hinchliffe, Robert Bain, Ajay Vora, David R. Bentley, Mark T. Ross, Anthony V. Moorman, Christine J. Harrison
Publikováno v:
Leukemia. 37:529-538
Incorporating genetics into risk-stratification for treatment of childhood B-progenitor acute lymphoblastic leukaemia (B-ALL) has contributed significantly to improved survival. In about 30% B-ALL (B-other-ALL) without well-established chromosomal ch