Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Christine Iacobuzio Donahue"'
Autor:
Ankit Chhoda, Anup Sharma, Bethsebie Sailo, Haoyu Tang, Nensi Ruzgar, Wan Ying Tan, Lee Ying, Rishabh Khatri, Anand Narayanan, Shrikant Mane, Bony De Kumar, Laura D. Wood, Christine Iacobuzio-Donahue, Christopher L. Wolfgang, John W. Kunstman, Ronald R. Salem, James J. Farrell, Nita Ahuja
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-8 (2023)
Abstract Background Intraductal papillary mucinous neoplasms (IPMNs), a type of cystic pancreatic cancer (PC) precursors, are increasingly identified on cross-sectional imaging and present a significant diagnostic challenge. While surgical resection
Externí odkaz:
https://doaj.org/article/546ba8af962b49deaa4afd35f88e5578
Autor:
Matthew E. Bechard, Rana Smalling, Akimasa Hayashi, Yi Zhong, Anna E. Word, Sydney L. Campbell, Amanda V. Tran, Vivian L. Weiss, Christine Iacobuzio-Donahue, Kathryn E. Wellen, Oliver G. McDonald
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Distant metastases from pancreatic cancer patients were previously reported by the authors to be dependent on the glucose-metabolizing enzyme phosphogluconate dehydrogenase (PGD). Here the authors report a novel metabolic adaptation that that stably
Externí odkaz:
https://doaj.org/article/4506861df93c451294cd63802d5a994b
Autor:
Heather J. Landau, Venkata Yellapantula, Benjamin T. Diamond, Even H. Rustad, Kylee H. Maclachlan, Gunes Gundem, Juan Medina-Martinez, Juan Arango Ossa, Max F. Levine, Yangyu Zhou, Rajya Kappagantula, Priscilla Baez, Marc Attiyeh, Alvin Makohon-Moore, Lance Zhang, Eileen M. Boyle, Cody Ashby, Patrick Blaney, Minal Patel, Yanming Zhang, Ahmet Dogan, David J. Chung, Sergio Giralt, Oscar B. Lahoud, Jonathan U. Peled, Michael Scordo, Gunjan Shah, Hani Hassoun, Neha S. Korde, Alexander M. Lesokhin, Sydney Lu, Sham Mailankody, Urvi Shah, Eric Smith, Malin L. Hultcrantz, Gary A. Ulaner, Frits van Rhee, Gareth J. Morgan, Ola Landgren, Elli Papaemmanuil, Christine Iacobuzio-Donahue, Francesco Maura
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
In multiple myeloma, disease progresses via seeding to different anatomic sites and clonal expansion. Here, utilising autopsy material, the authors show that systemic seeding accelerates at relapse following treatment.
Externí odkaz:
https://doaj.org/article/79126e7bfea74892ac4947e64f7abb17
Autor:
Alison P. Klein, Ralph H. Hruban, Bert Vogelstein, Kenneth W. Kinzler, Nickolas Papadopoulos, James R. Eshleman, Rachel Karchin, Michael Goggins, Peter P. Zandi, Laura D. Wood, Christopher L. Wolfgang, Yuxuan Wang, Alyssa L. Smith, Andrew D. Rhim, James B. Potash, Mehdi Pirooznia, Jennifer Parla, Noushin Niknafs, K. Wyatt McMahon, Richard W. McCombie, Alvin Makohon-Moore, Melissa Kramer, Christine Iacobuzio-Donahue, Joseph M. Herman, Fernando S. Goes, Christopher Douville, Erica J. Childs, Michele L. Cote, Yun-Ching Chen, Kari G. Chaffee, Jennifer Axilbund, Syed Z. Ali, George Zogopoulos, Sapna Syngal, Elena Stoffel, Ann G. Schwartz, Anil K. Rustgi, Sara H. Olson, Robert C. Kurtz, Steven Gallinger, Randall Brand, Melissa L. Bondy, Gloria M. Petersen, Alexis L. Norris, Nicholas J. Roberts
Supplementary Tables S1 - S12. Supplementary Table S1. Prioritization of candidate FPC susceptibility genes by private heterozygous PTVs. Supplementary Table S2. FPC patients harboring a private PTVs ASXL1, DNMT3A, and TET2. Supplementary Table S3. 8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::575bafdf79112f2f0bd50501c80d81de
https://doi.org/10.1158/2159-8290.22531232.v1
https://doi.org/10.1158/2159-8290.22531232.v1
Autor:
Eileen M. O'Reilly, Christine Iacobuzio-Donahue, Marinela Capanu, Christopher Crane, David P. Kelsen, Kenneth H. Yu, Fiyinfolu Balogun, Fergus Keane, Anna M. Varghese, Marsha Reyngold, Shigeaki Umeda, Joanne F. Chou, Daniella Forman, Chaitanya Bandlamudi, Catherine A. O'Connor, Wungki Park
Supplementary Figure from Clinico-genomic Characterization of ATM and HRD in Pancreas Cancer: Application for Practice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d02dd03e584fdd44e38ae775d950cad
https://doi.org/10.1158/1078-0432.22488417
https://doi.org/10.1158/1078-0432.22488417
Autor:
Eileen M. O'Reilly, Christine Iacobuzio-Donahue, Marinela Capanu, Christopher Crane, David P. Kelsen, Kenneth H. Yu, Fiyinfolu Balogun, Fergus Keane, Anna M. Varghese, Marsha Reyngold, Shigeaki Umeda, Joanne F. Chou, Daniella Forman, Chaitanya Bandlamudi, Catherine A. O'Connor, Wungki Park
Supplementary Data from Clinico-genomic Characterization of ATM and HRD in Pancreas Cancer: Application for Practice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0550dabfb72da97336c9727af9f81a06
https://doi.org/10.1158/1078-0432.22488435.v1
https://doi.org/10.1158/1078-0432.22488435.v1
Autor:
Eileen M. O'Reilly, Christine Iacobuzio-Donahue, Marinela Capanu, Christopher Crane, David P. Kelsen, Kenneth H. Yu, Fiyinfolu Balogun, Fergus Keane, Anna M. Varghese, Marsha Reyngold, Shigeaki Umeda, Joanne F. Chou, Daniella Forman, Chaitanya Bandlamudi, Catherine A. O'Connor, Wungki Park
Purpose:Characterizing germline and somatic ATM variants (gATMm, sATMm) zygosity and their contribution to homologous recombination deficiency (HRD) is important for therapeutic strategy in pancreatic ductal adenocarcinoma (PDAC).Experimental Design:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af45f3d05c721b60d9d261257f758660
https://doi.org/10.1158/1078-0432.c.6532713
https://doi.org/10.1158/1078-0432.c.6532713
Autor:
Manuel Hidalgo, Anirban Maitra, Ralph H. Hruban, James Eshleman, Wells Messersmith, Charles Yeo, Piotr Kulesza, Soner Altiok, Maria L. Amador, Nadia Bouraoud, Hossein Salimi-Moosavi, Sharat Singh, Koji Tanaka, Hidekazu Kuramochi, Peter V. Danenberg, Kathleen Danenberg, Chanjusn Shi, Collins Karikari, Christine Iacobuzio-Donahue, Xianfeng Zhang, George Cusatis, Antonio Jimeno, Belen Rubio-Viqueira
Supplementary Table 1 from An In vivo Platform for Translational Drug Development in Pancreatic Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::943fec57a1fd875cd2d0499551e88cdc
https://doi.org/10.1158/1078-0432.22441180.v1
https://doi.org/10.1158/1078-0432.22441180.v1
Autor:
Manuel Hidalgo, Anirban Maitra, Ralph H. Hruban, James Eshleman, Wells Messersmith, Charles Yeo, Piotr Kulesza, Soner Altiok, Maria L. Amador, Nadia Bouraoud, Hossein Salimi-Moosavi, Sharat Singh, Koji Tanaka, Hidekazu Kuramochi, Peter V. Danenberg, Kathleen Danenberg, Chanjusn Shi, Collins Karikari, Christine Iacobuzio-Donahue, Xianfeng Zhang, George Cusatis, Antonio Jimeno, Belen Rubio-Viqueira
Effective development of targeted anticancer agents includes the definition of the optimal biological dose and biomarkers of drug activity. Currently available preclinical models are not optimal to this end. We aimed at generating a model for transla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23ac3bad339ffe7396dfca1d242b486c
https://doi.org/10.1158/1078-0432.c.6518317.v1
https://doi.org/10.1158/1078-0432.c.6518317.v1
Autor:
Nita Ahuja, Kornel E. Schuebel, Manon Van Engeland, Stephen B. Baylin, James G. Herman, Katja Bierau, Christine Iacobuzio-Donahue, Frank A. Oort, Gerrit A. Meijer, Reinhold W. Stockbrügger, Daisy M.A.E. Jonkers, Carolina A.J. Khalid-de Bakker, Kim M. Smits, Adriaan P. de Bruïne, Wolfram Kleeberger, Timothy A. Chan, Joost Louwagie, Leander Van Neste, Kelly E. McGarvey, Joo Mi Yi, Mashaal Dhir, Sabine C. Glöckner
Supplementary Table 1 from Methylation of TFPI2 in Stool DNA: A Potential Novel Biomarker for the Detection of Colorectal Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47092e8549d2fd93b46ad11f8fd1ecd3
https://doi.org/10.1158/0008-5472.22376849.v1
https://doi.org/10.1158/0008-5472.22376849.v1