Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Christine Hui Shan Chan"'
Autor:
Murni Tio, Rujing Wen, Cai Ning Choo, Jian Bin Tan, Aaron Chua, Bin Xiao, Jeyapriya Rajameenakshi Sundaram, Christine Hui Shan Chan, Eng-King Tan
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-23 (2024)
Abstract Background Mutations in CHCHD2 have been linked to Parkinson’s disease, however, their exact pathophysiologic roles are unclear. The p32 protein has been suggested to interact with CHCHD2, however, the physiological functions of such inter
Externí odkaz:
https://doaj.org/article/6b0c5e5c904f4378a64375f261a25084
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 486 (2023)
Synaptic dysfunction may underlie the pathophysiology of Parkinson’s disease (PD), a presently incurable condition characterized by motor and cognitive symptoms. Here, we used quantitative proteomics to study the role of PHD Finger Protein 8 (PHF8)
Externí odkaz:
https://doaj.org/article/ce30b2eb3dfb4a2f8615958f85e4e2c6
Autor:
Nicodemus E. Oey, Puneet Opal, Louis C.S. Tan, Francisco Cardoso, KRay R. Chaudhuri, Carlo Colosimo, Yun Cheng Wu, Pramod Kumar Pal, Beomseok Jeon, Shen-Yang Lim, Daniel Truong, Werner Poewe, Eng-King Tan, Alberto Albanese, H.A. Jinnah, Christine Hui Shan Chan
Publikováno v:
Parkinsonism & Related Disorders
Highlights • COVID-19 has significant impact on PD research and education activities. • Country-specific restrictions may pose challenges to PD research and require careful adaptations. • Neurological Symptoms of COVID-19 may overlap with PD.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd18fd96fcd52be3f375720b9df320a5
http://hdl.handle.net/10807/172685
http://hdl.handle.net/10807/172685
Publikováno v:
Brain, Behavior, and Immunity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::569c1da8783ef3516f79c6defd70a063
Autor:
Christine Hui Shan Chan, Eng-King Tan
Publikováno v:
Archives of Medical Research
The COVID-19 pandemic has kicked off a global race to launch clinical trials of experimental vaccines and treatments for the coronavirus. Worldwide, as resources are directed toward accelerating the research into unravelling the mechanism of COVID-19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::477b5a89dbeecb81215d8474b8f93a3d
http://europepmc.org/articles/PMC7260578
http://europepmc.org/articles/PMC7260578
Autor:
Alberto Albanese, H.A. Jinnah, Puneet Opal, Daniel Truong, Yun Cheng Wu, Werner Poewe, Francisco Cardoso, Carlo Colosimo, Christine Hui Shan Chan, K. Ray Chaudhuri, Shen-Yang Lim, Beomseok Jeon, Eng-King Tan, Louis C. Tan, Pramod Kumar Pal
Publikováno v:
Journal of the Neurological Sciences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::babf41bbf46a57802b04c52c8b202262
https://doi.org/10.1016/j.jns.2020.117105
https://doi.org/10.1016/j.jns.2020.117105
Publikováno v:
Cell Adhesion & Migration. 5:463-471
Recent findings suggest that Ring finger protein 146 (RNF146), also called Iduna, have neuroprotective property due to its inhibition of Parthanatos via binding with Poly(ADP-ribose) (PAR). The Parthanatos is a PAR dependent cell death that has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a525b17b1bbcfeeaf5f1ea564fdb2c9
https://doi.org/10.4161/cam.5.6.18356
https://doi.org/10.4161/cam.5.6.18356
Autor:
Patrick Ho, Tit Meng Lim, Zhi Dong Zhou, Shin Hui Ng, Christine Hui Shan Chan, Xiao-Dong Zhang, Shao Ping Xie, Fathima Shaffra Refai, Eng-King Tan
Publikováno v:
Free radical biologymedicine. 68
PINK1 mutations cause autosomal recessive forms of Parkinson disease (PD). Previous studies suggest that the neuroprotective function of wild-type (WT) PINK1 is related to mitochondrial homeostasis. PINK1 can also localize to the cytosol; however, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbffee195f65ade8c323f24cfd4b725d
https://pubmed.ncbi.nlm.nih.gov/24374372
https://pubmed.ncbi.nlm.nih.gov/24374372
Autor:
Eng-King Tan, Xiao-hong Xu, Zhi-Cheng Xiao, Christine Hui Shan Chan, Zhi Dong Zhou, Quan-Hong Ma
Publikováno v:
Cell adhesionmigration. 5(4)
The amyloid-beta (Aβ) peptide is the derivative of amyloid precursor protein (APP) generated through sequential proteolytic processing by β- and γ-secretases. Excessive accumulation of Aβ, the main constituent of amyloid plaques, has been implica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70f4bc99afc0dcff9777a6a587e0c57e
https://pubmed.ncbi.nlm.nih.gov/21785276
https://pubmed.ncbi.nlm.nih.gov/21785276