Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Christine Hinkle"'
Autor:
Rachana Shah, Sean M O'Neill, Christine Hinkle, Jennifer Caughey, Stephen Stephan, Emma Lynch, Kate Bermingham, Gina Lynch, Rexford S Ahima, Muredach P Reilly
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138317 (2015)
The fractalkine (CX3CL1-CX3CR1) chemokine system is associated with obesity-related inflammation and type 2 diabetes, but data on effects of Cx3cr1 deficiency on metabolic pathways is contradictory. We examined male C57BL/6 Cx3cr1-/- mice on chow and
Externí odkaz:
https://doaj.org/article/26594b9107624994bd947803859d1dc3
Autor:
Hanrui Zhang, Wenjun Li, Christine Hinkle, Xuan Zhang, Robert Bauer, Junichiro Tohyama, Kevin Patel, Kevin Trindade, Jennie Lin, John Millar, Jeffrey Billheimer, Wenli Yang, Edward Morrisey, Michael C Phillips, Daniel J Rader, Muredach P Reilly
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 35
Loss-of-function mutations of lysosomal acid lipase ( LIPA or LAL) are the cause of the rare lysosomal disorders, Wolman disease and Cholesteryl Ester Storage Disease (CESD), which manifest with hepatomegaly, hyperlipidemia and premature atherosclero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9668e0e2add8d7fe60ab99c4e33d9727
https://doi.org/10.1161/atvb.35.suppl_1.329
https://doi.org/10.1161/atvb.35.suppl_1.329
Autor:
Hanrui Zhang, Chenyi Xue, Rachel L Ballantyne, Rhia Shah, Kate Bermingham, Christine Hinkle, Wenli Yang, Sager Gosai, Brian Gregory, Edward E Morrisey, Mingyao Li, Daniel J Rader, Muredach P Reilly
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 34
Macrophages respond to inflammatory stimuli by modulating gene expression. Whether long intergenic noncoding RNAs (lincRNA) play a regulatory role in human macrophage inflammatory response is unknown. Therefore, we performed RNA-Seq in human PBMC-der
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6a80c472594f790f677d20183b1e43f
https://doi.org/10.1161/atvb.34.suppl_1.364
https://doi.org/10.1161/atvb.34.suppl_1.364
Autor:
Hanrui Zhang, Rhia Shah, Kate Bermingham, Christine Hinkle, Amrith Rodrigues, Marina Cuchel, Ying Liu, Wenli Yang, Daniel VanDorn, Stella Chou, Edward E Morrisey, Daniel J Rader, Muredach P Reilly
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 34
Tangier disease (TD) is an autosomal recessive disorder caused by mutations in the ATP-binding cassette transporter A1 (ABCA1). These result in a greatly reduced ability to transport cholesterol out of cells, leading to the accumulation of cholestero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1610447cb61f61cb471bb2711b87037c
https://doi.org/10.1161/atvb.34.suppl_1.190
https://doi.org/10.1161/atvb.34.suppl_1.190
Autor:
Sean P Heffron, Nehal N Mehta, Margarita de la Llera-Moya, Karen Terembula, Christine Hinkle, Megan Wolfe, Muredach P Reilly
Publikováno v:
Circulation. 116
Introduction: Chronic low-grade inflammation is thought to induce atherogenic changes in HDL function. Indeed, we have demonstrated HDL particle remodeling during experimental human endotoxemia (3ng/kg). However, this model is associated with marked
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::818f94c4a8c553d251ac61c34e11b853
https://doi.org/10.1161/circ.116.suppl_16.ii_220-a
https://doi.org/10.1161/circ.116.suppl_16.ii_220-a