Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Christine Hermannstädter"'
Autor:
Birgit Luber, Heinz Höfler, Claus Hann von Weyhern, Rupert Langer, Sandra Rauser, Karl-Friedrich Becker, Christine Hermannstädter, Gisela Keller, Justus Duyster, Jörg Mages, Margit Fuchs, Axel Walch, Anja Bremm
Mutations of the tumor suppressor E-cadherin and overexpression of the receptor tyrosine kinase epidermal growth factor receptor (EGFR) are among the most frequent genetic alterations associated with diffuse-type gastric carcinoma. Accumulating evide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbe196a58ac9f6a17004403f5e5b561d
https://doi.org/10.1158/0008-5472.c.6497694
https://doi.org/10.1158/0008-5472.c.6497694
Autor:
Birgit Luber, Heinz Höfler, Claus Hann von Weyhern, Rupert Langer, Sandra Rauser, Karl-Friedrich Becker, Christine Hermannstädter, Gisela Keller, Justus Duyster, Jörg Mages, Margit Fuchs, Axel Walch, Anja Bremm
Supplementary Tables S1-S3 from Enhanced Activation of Epidermal Growth Factor Receptor Caused by Tumor-Derived E-Cadherin Mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2831a1674cb228039d2380dd78da2f2
https://doi.org/10.1158/0008-5472.22375053.v1
https://doi.org/10.1158/0008-5472.22375053.v1
Autor:
Birgit Luber, Heinz Höfler, Claus Hann von Weyhern, Rupert Langer, Sandra Rauser, Karl-Friedrich Becker, Christine Hermannstädter, Gisela Keller, Justus Duyster, Jörg Mages, Margit Fuchs, Axel Walch, Anja Bremm
Supplementary Results, Figure 1, Methods and Materials from Enhanced Activation of Epidermal Growth Factor Receptor Caused by Tumor-Derived E-Cadherin Mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::691af4e0fc257797b18be9fe98538f57
https://doi.org/10.1158/0008-5472.22375056
https://doi.org/10.1158/0008-5472.22375056
Autor:
Ben C. Sheldon, Niels Jeroen Dingemanse, Piet J. Drent, Christine Hermannstädter, John L. Quinn, Kees van Oers, Bart Kempenaers, Joost M. Tinbergen, Erik Matthysen, Miriam Liedvogel, Thijs van Overveld, Karen M. Bouwman, Peter Korsten, Samantha C. Patrick, Jakob C. Mueller
Publikováno v:
Molecular Ecology. 19:832-843
Polymorphisms in the dopamine receptor D4 gene (DRD4) have been related to individual variation in novelty-seeking or exploratory behaviour in a variety of animals, including humans. Recently, the human DRD4 orthologue was sequenced in a wild bird, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efd8973c40f7280a4baf854049dbf2d0
https://doi.org/10.1111/j.1365-294x.2009.04518.x
https://doi.org/10.1111/j.1365-294x.2009.04518.x
Autor:
Stefan Seidl, Raymonde Busch, Sonja Gillen, Marcus Feith, Mario Sarbia, Joëlle Deplazes, Rupert Langer, Axel Walch, Heinz Höfler, Birgit Luber, Christine Hermannstädter, Sandra Rauser, Claus Hann von Weyhern
Publikováno v:
Modern Pathology. 21:544-552
Rho GTPases are a family of major regulators of E-cadherin-mediated cell adhesion that are implicated in the carcinogenic process by deregulated expression of the family members itself or of upstream modulators or downstream effectors. Combined inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b75413203f2c8e2bb46e6ec17786485
https://doi.org/10.1038/modpathol.2008.3
https://doi.org/10.1038/modpathol.2008.3
Autor:
Georg Häcker, Birgit Luber, Peter Hutzler, Margit Fuchs, Ferdinand Haller, Heinz Höfler, Christine Hermannstädter
Publikováno v:
Experimental Cell Research. 314:153-163
E-Cadherin-mediated cell-cell adhesion plays a key role in epithelial cell survival and loss of E-cadherin or beta-catenin expression is associated with invasive tumor growth. Somatic E-cadherin mutations have been identified in sporadic diffuse-type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b44e468107970a12d0694db50a0f774
https://doi.org/10.1016/j.yexcr.2007.09.004
https://doi.org/10.1016/j.yexcr.2007.09.004
Autor:
Birgit Luber, Christine Hermannstädter, Peter Hutzler, Gabriele Handschuh, Heinz Höfler, Ingrid Brunner, Margit Fuchs
Publikováno v:
Cell Motility and the Cytoskeleton. 59:50-61
E-Cadherin regulates epithelial cell adhesion and is critical for the maintenance of tissue integrity. In sporadic diffuse-type gastric carcinoma, mutations of the E-cadherin gene are frequently observed that predominantly affect putative calcium bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7a74058519d637d5238c582a0018a18
https://doi.org/10.1002/cm.20019
https://doi.org/10.1002/cm.20019
Autor:
Christine Hermannstädter, Pjotr Knyazev, Birgit Luber, Katja Specht, Peter Hutzler, Raymonde Busch, Axel Ullrich, Heinz Höfler, Erika Rosivatz, Margit Fuchs
Publikováno v:
Journal of Cellular Physiology. 202:805-813
Tumor progression is characterized by loss of cell adhesion and increase of invasion and metastasis. The cell adhesion molecule E-cadherin is frequently down-regulated or mutated in tumors. In addition to down-regulation of cell adhesion, degradation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90f0748736a90e594b1cd91607d00c96
https://doi.org/10.1002/jcp.20192
https://doi.org/10.1002/jcp.20192
Autor:
Falko Fend, Edgardo Reyes-Gutiérrez, Christine Hermannstädter, Claudia Dominguez-Fonseca, Jörg Nährig, Armando Gamboa-Domínguez, Karl-Friedrich Becker, Raymonde Busch, Heinz Höfler, Birgit Luber, Ingrid Becker, Dan Green, Arturo Angeles-Angeles, Leticia Quintanilla-Martinez
Publikováno v:
Modern Pathology. 17:579-587
The aim of the study was to determine epidermal growth factor receptor (EGFR) expression in gastric adenocarcinoma by standardized immunohistochemistry and to correlate EGFR expression with clinical features and patient survival. EGFR expression was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6263efc3baacf7a26742d4f7fe2b4f8a
https://doi.org/10.1038/modpathol.3800085
https://doi.org/10.1038/modpathol.3800085
Autor:
Heinz Höfler, Sieglinde Haye, Armando Gamboa-Domínguez, Holger Kalthoff, Marcus Kremer, Leticia Quintanilla-Martinez, Birgit Luber, Christine Hermannstädter, Margit Fuchs, Raymonde Busch, Erika Rosivatz
Publikováno v:
Carcinogenesis 24, 1879-1886 (2003)
In this study, we investigated whether tumor-associated E-cadherin mutations impair the tumor-suppressive function of the cell adhesion molecule and influence metastasis formation in a severe combined immunodeficiency mouse model. The investigated E-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e0861518296e64a1be4bf8358b8dcd
https://doi.org/10.1093/carcin/bgg148
https://doi.org/10.1093/carcin/bgg148