Clinical and cost‐effectiveness of pessary self‐management versus clinic-based care for pelvic organ prolapse in women: the TOPSY RCT with process evaluation

Autor: Carol Bugge, Suzanne Hagen, Andrew Elders, Helen Mason, Kirsteen Goodman, Melanie Dembinsky, Lynn Melone, Catherine Best, Sarkis Manoukian, Lucy Dwyer, Aethele Khunda, Margaret Graham, Wael Agur, Suzanne Breeman, Jane Culverhouse, Angela Forrest, Mark Forrest, Karen Guerrero, Christine Hemming, Doreen McClurg, John Norrie, Ranee Thakar, Rohna Kearney

Publikováno v: Health Technology Assessment, Vol 28, Iss 23 (2024)

Background Pelvic organ prolapse is common, causes unpleasant symptoms and negatively affects women’s quality of life. In the UK, most women with pelvic organ prolapse attend clinics for pessary care. Objectives To determine the clinical effectiven

Externí odkaz: https://doaj.org/article/1a4e38a8d04346f3aa237f9e417483b7

Theoretical and practical development of the TOPSY self-management intervention for women who use a vaginal pessary for pelvic organ prolapse

Autor: Lucy Dwyer, Carol Bugge, Suzanne Hagen, Kirsteen Goodman, Wael Agur, Melanie Dembinsky, Margaret Graham, Karen Guerrero, Christine Hemming, Aethele Khunda, Doreen McClurg, Lynn Melone, Ranee Thakar, Rohna Kearney, The TOPSY Team

Publikováno v: Trials, Vol 23, Iss 1, Pp 1-10 (2022)

Abstract Background Pelvic organ prolapse (POP) is a common condition in women, where the downward descent of pelvic organs into the vagina causes symptoms which impacts quality of life. Vaginal pessaries offer an effective alternative to surgery for

Externí odkaz: https://doaj.org/article/2bf0bbf48dd74635a94a48d7f387a97f

Clinical and cost-effectiveness of vaginal pessary self-management compared to clinic-based care for pelvic organ prolapse: protocol for the TOPSY randomised controlled trial

Autor: Suzanne Hagen, Rohna Kearney, Kirsteen Goodman, Lynn Melone, Andrew Elders, Sarkis Manoukian, Wael Agur, Catherine Best, Suzanne Breeman, Melanie Dembinsky, Lucy Dwyer, Mark Forrest, Margaret Graham, Karen Guerrero, Christine Hemming, Aethele Khunda, Helen Mason, Doreen McClurg, John Norrie, Anastasia Karachalia-Sandri, Ranee Thakar, Carol Bugge

Publikováno v: Trials, Vol 21, Iss 1, Pp 1-13 (2020)

Abstract Background Pelvic organ prolapse (or prolapse) is a common condition in women where the pelvic organs (bladder, bowel or womb) descend into the vagina and cause distressing symptoms that adversely affect quality of life. Many women will use

Externí odkaz: https://doaj.org/article/bf51714f76a04f8881239eeb2a09d7c4

Clinical effectiveness and cost-effectiveness of surgical options for the management of anterior and/or posterior vaginal wall prolapse: two randomised controlled trials within a comprehensive cohort study – results from the PROSPECT Study

Autor: Cathryn Glazener, Suzanne Breeman, Andrew Elders, Christine Hemming, Kevin Cooper, Robert Freeman, Anthony Smith, Suzanne Hagen, Isobel Montgomery, Mary Kilonzo, Dwayne Boyers, Alison McDonald, Gladys McPherson, Graeme MacLennan, John Norrie

Publikováno v: Health Technology Assessment, Vol 20, Iss 95 (2016)

Background: The use of mesh in prolapse surgery is controversial, leading to a number of enquiries into its safety and efficacy. Objective: To compare synthetic non-absorbable mesh inlay, biological graft and mesh kit with a standard repair in terms

Externí odkaz: https://doaj.org/article/ba43304d390849c3900009eac74366f6

Mesh inlay, mesh kit or native tissue repair for women having repeat anterior or posterior prolapse surgery: randomised controlled trial (PROSPECT)

Autor: Isobel Montgomery, Alison McDonald, Suzanne Hagen, Mary Kilonzo, Graeme MacLennan, Arb Smith, Kevin Cooper, Suzanne Breeman, Andrew Elders, Dwayne Boyers, Gladys McPherson, C. M. A. Glazener, Christine Hemming, Robert Freeman, John Norrie, Fiona Reid

Publikováno v: 2020, ' Mesh inlay, mesh kit or native tissue repair for women having repeat anterior or posterior prolapse surgery : randomised controlled trial (PROSPECT) ', BJOG: An International Journal of Obstetrics and Gynaecology . https://doi.org/10.1111/1471-0528.16197
Glazener, C, Freeman, R, Breeman, S & Reid, F 2020, ' Mesh inlay, mesh kit or native tissue repair for women having repeat anterior or posterior prolapse surgery: randomised controlled trial (PROSPECT) ', BJOG: an international journal of obstetrics and gynaecology . https://doi.org/10.1111/1471-0528.16197

Objective To compare standard (native tissue) repair with synthetic mesh inlays or mesh kits. Design Randomised controlled trial. Setting Thirty-three UK hospitals. Population Women having surgery for recurrent prolapse. Methods Women recruited using

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::857e85bb07563af6bb138cc5c1b4ecda
https://doi.org/10.1111/1471-0528.16197