Výsledky vyhledávání - "Christine Hayes"

Akademický článek

A novel colorectal cancer test combining microsatellite instability and BRAF/RAS analysis: Clinical validation and impact on Lynch syndrome screening

Autor: Richard Gallon, Patricia Herrero-Belmonte, Rachel Phelps, Christine Hayes, Elizabeth Sollars, Daniel Egan, Helena Spiewak, Sam Nalty, Sarah Mills, Peh Sun Loo, Gillian M. Borthwick, Mauro Santibanez-Koref, John Burn, Ciaron McAnulty, Michael S. Jackson

Publikováno v: BJC Reports, Vol 2, Iss 1, Pp 1-11 (2024)

Abstract Background Lynch syndrome (LS) is under-diagnosed. UK National Institute for Health and Care Excellence guidelines recommend multistep molecular testing of all colorectal cancers (CRCs) to screen for LS. However, the complexity of the pathwa

Externí odkaz: https://doaj.org/article/a83bafbb709a45cea3903a4046c1df92

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Akademický článek

Mismatch repair deficiency testing in Lynch syndrome-associated urothelial tumors

Autor: Maria Rasmussen, Peter Sowter, Richard Gallon, Jon Ambæk Durhuus, Christine Hayes, Ove Andersen, Mef Nilbert, Lone Schejbel, Estrid Høgdall, Mauro Santibanez-Koref, Michael S. Jackson, John Burn, Christina Therkildsen

Publikováno v: Frontiers in Oncology, Vol 13 (2023)

IntroductionLynch syndrome-associated cancer develops due to germline pathogenic variants in one of the mismatch repair (MMR) genes, MLH1, MSH2, MSH6 or PMS2. Somatic second hits in tumors cause MMR deficiency, testing for which is used to screen for

Externí odkaz: https://doaj.org/article/aefb11b3469d4b6386bfbc662f64a362

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Elektronická kniha

Introduction to the Bible

Autor: Christine Hayes

This book examines the small library of 24 books common to all Jewish and Christian Bibles?books that preserve the efforts of diverse writers over a span of many centuries to make sense of their personal experiences and those of their people, the an

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Efficacy of exercise interventions for women during and after gynaecological cancer treatment – a systematic scoping review

Autor: Grace Laura Rose, Elizabeth Mary Stewart, Briana Kristine Clifford, Tom George Bailey, Alexandra Jane Rush, Claudia Rose Abbott, Sandra Christine Hayes, Andreas Obermair, Alexandra Leigh McCarthy

Publikováno v: Supportive Care in Cancer. 31

Purpose To systematically synthesise evidence of exercise intervention efficacy for physical/psychosocial outcomes that matter to women during/following treatment for gynaecological cancer. Methods Five databases were searched (PubMed, EMBASE, CINAHL

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b0e19f6f4308cfc96dbf4d873be1c85a
https://doi.org/10.1007/s00520-023-07790-8

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Constitutional Microsatellite Instability, Genotype, and Phenotype Correlations in Constitutional Mismatch Repair Deficiency

Autor: Richard Gallon, Rachel Phelps, Christine Hayes, Laurence Brugieres, Léa Guerrini-Rousseau, Chrystelle Colas, Martine Muleris, Neil A.J. Ryan, D. Gareth Evans, Hannah Grice, Emily Jessop, Annabel Kunzemann-Martinez, Lilla Marshall, Esther Schamschula, Klaus Oberhuber, Amedeo A. Azizi, Hagit Baris Feldman, Andreas Beilken, Nina Brauer, Triantafyllia Brozou, Karin Dahan, Ugur Demirsoy, Benoît Florkin, William Foulkes, Danuta Januszkiewicz-Lewandowska, Kristi J. Jones, Christian P. Kratz, Stephan Lobitz, Julia Meade, Michaela Nathrath, Hans-Jürgen Pander, Claudia Perne, Iman Ragab, Tim Ripperger, Thorsten Rosenbaum, Daniel Rueda, Tomasz Sarosiek, Astrid Sehested, Isabel Spier, Manon Suerink, Stefanie-Yvonne Zimmermann, Johannes Zschocke, Gillian M. Borthwick, Katharina Wimmer, John Burn, Michael S. Jackson, Mauro Santibanez-Koref

Publikováno v: Gallon, R, Phelps, R, Hayes, C, Brugieres, L, Guerrini-Rousseau, L, Colas, C, Muleris, M, Ryan, N A J, Evans, D G, Grice, H, Jessop, E, Kunzemann-Martinez, A, Marshall, L, Schamschula, E, Oberhuber, K, Azizi, A A, Baris Feldman, H, Beilken, A, Brauer, N, Brozou, T, Dahan, K, Demirsoy, U, Florkin, B, Foulkes, W, Januszkiewicz-Lewandowska, D, Jones, K J, Kratz, C P, Lobitz, S, Meade, J, Nathrath, M, Pander, H-J, Perne, C, Ragab, I, Ripperger, T, Rosenbaum, T, Rueda, D, Sarosiek, T, Sehested, A, Spier, I, Suerink, M, Zimmermann, S-Y, Zschocke, J, Borthwick, G M, Wimmer, K, Burn, J, Jackson, M S & Santibanez-Koref, M 2023, ' Constitutional Microsatellite Instability, Genotype, and Phenotype Correlations in Constitutional Mismatch Repair Deficiency ', Gastroenterology, vol. 164, no. 4, pp. 579-592.e8 . https://doi.org/10.1053/j.gastro.2022.12.017

BACKGROUND & AIMS: Constitutional mismatch repair deficiency (CMMRD) is a rare recessive childhood cancer predisposition syndrome caused by germline mismatch repair variants. Constitutional microsatellite instability (cMSI) is a CMMRD diagnostic hall

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2f9c31dd5604b2681e0b38c8e5c76ee
https://www.pure.ed.ac.uk/ws/files/342899380/1_s2.0_S0016508522014445_main.pdf

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